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42 Possible Causes for Cortical Thinning, Heavy Metal Poisoning

  • Rickets

    Rickets in infants attributable to inadequate vitamin D intake and decreased exposure to sunlight continues to be reported in the United States. It is recommended that all infants, including those who are exclusively breastfed, have a minimum intake of 200 IU of vitamin D per day beginning during the first 2 months[…][ncbi.nlm.nih.gov]

  • Osteoporosis

    , Drug Overdose, and Envenomation -- Chapter 449: Heavy Metal Poisoning -- Chapter 450: Poisoning and Drug Overdose -- Part 23: Atlases -- Chapter A1: Atlas of Rashes Associated[worldcat.org] The main radiographic features of generalized osteoporosis are cortical thinning and increased radiolucency. 1 Vertebral fractures are a frequent complication of osteoporosis[web.archive.org] cortical bone and marked bone loss in the anterior and posterior 25% of the tibial plateau should require special attention when osteoporotic patients require fracture fixation[ncbi.nlm.nih.gov]

  • Traumatic Brain Injury

    Blast-Exposed Veterans With Mild Traumatic Brain Injury Show Greater Frontal Cortical Thinning and Poorer Executive Functioning .[doi.org]

  • Nephrolithiasis

    metal chelator Penicillamine Curprimine, Depen Cystinuria, severe rheumatoid arthritis, Wilson disease, arsenic poisoning, lead toxicity, primary biliary cirrhosis ACE Inhibitor[effectivehealthcare.ahrq.gov] Cortical nephrocalcinosis may be seen on abdominal radiographs as thin peripheral lines of calcification (tram lines), diffusely dense renal shadows, or as diffuse punctate[radiologykey.com] […] chelator Acetohydroxamic acid Lithostat Renal calculi associated with chronic urinary tract infections with urease-splitting bacteria Reducing agent Tiopronin Thiola Cystinuria Heavy[effectivehealthcare.ahrq.gov]

  • Rheumatoid Arthritis

    Roldán, Agustín Escalante and Inmaculada del Rincón, Impaired arterial function associated with thinning of cortical bone in rheumatoid arthritis, Arthritis Care & Research[doi.org]

  • Osteomalacia

    Aluminium Lead See Lead poisoning Cadmium See Heavy metals urine Mineralisation defects (inherited) Hypophosphatasia Alkaline phosphatase, Amino acids urine (ethanolamine[rcpa.edu.au] Vitamin D -dependent rickets Type 1: calcitriol concentration Type 2: calcitriol concentration X‑ray Osteomalacia Low bone mineral density Thin cortices Looser zones ( pseudofractures[amboss.com] The skeleton is diffusely rarefied, and the cortices are thinned [effect of compensatory hyperparathyroidism] There is no subperiosteal resorption of bone in contrast to hyperparathyroidism[boneandspine.com]

  • Cerebellar Ataxia

    A, Axial T2 image shows cortical thinning and fissure enlargement in the vermis and cerebellar hemispheres.[ajnr.org] A, Coronal T2 image shows cortical thinning and loss of underlying white matter leading to enlarged fissures in the vermis and cerebellar hemispheres.[ajnr.org] B, Follow-up coronal T2 image 3 years later shows progressive cortical and white matter atrophy. Fig 2. Ataxia-telangiectasia.[ajnr.org]

  • Fanconi Syndrome

    It can also develop with vitamin D deficiency, kidney transplantation, heavy metal poisoning, and treatment with certain drugs.[the-medical-dictionary.com] A renal ultrasonogram in Patient III-5 (Panel D, longitudinal view of left kidney) shows cortical thinning, with normal echogenicity of the cortex and medulla (arrows) and[doi.org] Etiology FS in adults may be secondary to other causes, including autoimmune disorders, drugs, or heavy metal poisoning.[orpha.net]

  • Psychosis

    metal poisoning.[nmihi.com] Silveri, Cortical thinness and volume differences associated with marijuana abuse in emerging adults, Drug and Alcohol Dependence, 155, (275), (2015).[doi.org] thinning of frontal and temporal areas in SZ patients, which is correlated with deficits in several cognitive domains. 12 Cortical surface contraction, observed in both SZ[ncbi.nlm.nih.gov]

  • Schizophrenia

    Complete blood count Thyroid function tests Liver and kidney function tests Urinalysis to check substance abuse, heavy metal poisoning and pregnancy Imaging CT scan and MRI[symptoma.com] Patterns of cortical thinning in different subgroups of schizophrenia. The British Journal of Psychiatry: the Journal of Mental Science 206, 479 – 483.[doi.org] Original Article Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium Department of Psychology, Georgia[doi.org]

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