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40 Possible Causes for Cotton Wool Spots, Headache, Polydipsia

  • Multiple Myeloma

    CONCERNS AND DIAGNOSES: Herein, we describe an extraordinary rare case of multiple myeloma with initial presentation of a left sphenoid neoplasm resulting in left-sided headache[ncbi.nlm.nih.gov] Hypercalcemia may cause polyuria and polydipsia, muscle cramps, constipation, and a change in the patient’s mental status.[emedicine.medscape.com] A 72-year-old man, who had been in complete remission from multiple myeloma for 1 year after treatment that included lenalidomide, presented with confusion, headache, nausea[ncbi.nlm.nih.gov]

  • Temporal Arteritis

    The present case is an 81-year-old woman diagnosed with GCA, who initially presented with features similar to tension-type headache.[ncbi.nlm.nih.gov] One week later, there were multiple cotton wool spots in the posterior pole, a relative afferent pupillary defect, and subtle visual field loss in the left eye.[ncbi.nlm.nih.gov] An 81-year-old man presented with a right temporal headache that had persisted for one month.[ncbi.nlm.nih.gov]

  • Diabetes Mellitus Type 2

    There was no significant difference in the risk of cough, headache or hyperkalaemia when ARB was to placebo.[dx.doi.org] polydipsia.[en.wikipedia.org] wool spots are present, look carefully for the following features, but cotton wool spots themselves do not define pre-proliferative retinopathy): any venous beading any venous[web.archive.org]

  • Malignant Hypertension

    A 62-year-old man with a history of hypertension was referred secondary to bilateral temporal scotomas and persistent headache for 3 days.[ncbi.nlm.nih.gov] An 11-month-old girl presented with a history of failure to thrive, vomiting, polydipsia, polyuria and visual inattention.[ncbi.nlm.nih.gov] Cotton-wool spots, or cytoid bodies, are not exudates, but rather are retinal infarcts. Hypertensive optic neuropathy is a late finding.[ncbi.nlm.nih.gov]

  • Optic Nerve Infarction

    A 39-year-old man presented with headache, weight loss, bilateral subdural hematomas, pansinusitis, and visual loss.[ncbi.nlm.nih.gov] […] sonographer collected demographic and medical history via a structured case report form that included information on presenting signs and symptoms, length of symptoms (polyuria, polydipsia[westjem.com] Prior to optic nerve infarction, hyperemic swelling of the nerve and/or cotton wool spots in the macular area may be the only ophthalmologic finding ( Fig. 18–3 ).[entokey.com]

  • Diabetic Retinopathy

    Late-stage diabetic retinopathy symptoms include: Blurred vision Eye strain Headaches. Causes Diabetic retinopathy is an eye disease caused by complications of diabetes.[betterhealth.vic.gov.au] Symptoms of marked hyperglycemia include polyuria, polydipsia, weight loss, sometimes with polyphagia, and blurred vision.[doi.org] The first signs of nonproliferative retinopathy are Capillary microaneurysms Dot and blot retinal hemorrhages Hard exudates Cotton-wool spots (soft exudates) Hard exudates[merckmanuals.com]

  • Vasculitis

    Temporal arteritis is a form of vasculitis that involves the large- and medium-diameter arteries and leads to progressive headache.[ncbi.nlm.nih.gov] Patients should be warned about polyuria and polydipsia.[lupusinternational.com] Additional ophthalmic manifestations include isolated cotton-wool spots, cranial-nerve palsies, ocular hypotony, and pupillary abnormalities. 2 To detect these conditions,[dx.doi.org]

  • Granulomatosis with Polyangiitis

    A 54-year-old male, without any related medical history developed a severe headache.[ncbi.nlm.nih.gov] Following her prednisone taper, she experienced worsening galactorrhea, polyuria, and polydipsia, accompanied by headaches.[ajnr.org] Retinal vascular manifestations range from relatively benign cotton-wool spots, with or without associated intraretinal hemorrhages, to more severe vaso-occlusive disease,[aao.org]

  • Leukemia

    Pounding headaches iStock/AZarubaika Although not common, frequent pounding headaches may be a sign of leukemia-related anemia or even a life-threatening case of bleeding[rd.com] Dogs with hyper-calcemia present polydipsia and polyuria, and finally collapse. Thoracic cavity organs, as well as other lymph nodes, are more rarely affected.[ncbi.nlm.nih.gov] Those with retinopathy have more aggressive disease and therefore worse outcomes. [11, 12] The presence of cotton wool spots decreases the mean survival significantly. [13[emedicine.medscape.com]

  • Autoimmune Disease

    Other findings included serositis manifested by tachycardia, dyspnea and pleural effusions, headaches, and hair loss.[ncbi.nlm.nih.gov] Cotton-wool spots in a patient with systemic lupus erythematosus. FIGURE 10. Cotton-wool spots in a patient with systemic lupus erythematosus.[aafp.org] The common and most noticeable signs of type 1 diabetes are: Increased thirst (polydipsia) Frequent/increased urination (polyuria) Extreme tiredness (fatigue) Sudden or unexplained[diabetes.co.uk]

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