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160 Possible Causes for Cotton Wool Spots, Headache, Proteinuria

  • Preeclampsia

    The patient may experience severe headaches; pain in the stomach, dizziness and shortness of breath.[symptoma.com] This ischemic state can manifest as reduced arteriolar caliber and arteriovenous ratio, retinal haemorrhages, oedema and cotton wool spots secondary to arteriolar damage,[eyewiki.aao.org] CONCLUSIONS: The severity of preeclampsia cannot be determined by the level of proteinuria.[ncbi.nlm.nih.gov]

  • Multiple Myeloma

    A 72-year-old man, who had been in complete remission from multiple myeloma for 1 year after treatment that included lenalidomide, presented with confusion, headache, nausea[ncbi.nlm.nih.gov] Physical Examination On head, ears, eyes, nose, and throat (HEENT) examination, the eyes may show exudative macular detachment, retinal hemorrhage, or cotton-wool spots.[emedicine.medscape.com] Abstract Preeclampsia is the most common cause of proteinuria with hypertension during pregnancy.[ncbi.nlm.nih.gov]

  • Malignant Hypertension

    A 62-year-old man with a history of hypertension was referred secondary to bilateral temporal scotomas and persistent headache for 3 days.[ncbi.nlm.nih.gov] Cotton-wool spots, or cytoid bodies, are not exudates, but rather are retinal infarcts. Hypertensive optic neuropathy is a late finding.[ncbi.nlm.nih.gov] Mean proteinuria during follow-up is a fundamental prognostic factor for renal survival.[ncbi.nlm.nih.gov]

  • Hypertensive Encephalopathy

    Three patients are described who experienced headache from hypertension: one had acute headache from acute hypertension, one had daily, morning headaches from chronic hypertension[ncbi.nlm.nih.gov] On ophthalmoscopy, grade IV retinal changes are associated with hypertensive encephalopathy, [7] including papilledema, hemorrhage, exudates, and cotton-wool spots (see the[emedicine.medscape.com] The proteinuria resolved spontaneously.[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    The headache recurred with findings of cerebellar ataxia and obstructive hydrocephalus.[ncbi.nlm.nih.gov] Extensive cotton wool spots were observed in the right fundus, and retinal capillary occlusions were detected by OCT angiography of the left eye.[ncbi.nlm.nih.gov] We analyzed mean values of age, ESR, ESRp, CRP, ferritin and distribution of anti-dsDNA antibodies, C3 reduction, serositis, and erythrocyturia with proteinuria.[ncbi.nlm.nih.gov]

  • Weil's Disease

    Most cases involve flu-like symptoms (fever, chills, muscle aches, headaches).[cdc.gov] On the 7th day bilateral subconjunctival hemorrhages, anterior uveitis, and peripapillary cotton-wool spots were noted.[ncbi.nlm.nih.gov] […] thrombocytopenia, elevated blood urea nitrogen (BUN), creatinine, and liver transaminases (alanine and aspartate aminotransferases, or ALT and AST), hyperbilirubinemia, proteinuria[symptoma.com]

  • Bacterial Endocarditis

    BE patients (32-77 years) presented multiple (n 3) or single ischemic strokes (n 2) or encephalopathy and headache (n 2).[ncbi.nlm.nih.gov] They probably reflect microinfarcts, just like cotton wool spots, and occur in a litany of disorders, including essential hypertension, HIV, connective tissue disease, severe[hakeem-sy.com] Also a focal renal infarction, focal nephritis or diffuse glomerulonephritis is very common, resulting in microscopic haematuria and proteinuria.[gpnotebook.co.uk]

  • Polyarteritis Nodosa

    A 20-year-old man presented with diplopia, headaches, chronic abdominal pain, and weight loss.[ncbi.nlm.nih.gov] In the posterior pole, this may manifest as hypertensive retinopathy replete with macular star formation, cotton-wool spots, and intraretinal hemorrhage in patients with renal[aao.org] She was incidentally found to be hypertensive and had proteinuria. Skin biopsy showed leuco-cytoclastic vasculitis.[ncbi.nlm.nih.gov]

  • Systemic Scleroderma

    TMD symptoms (muscle pain on chewing, difficulty in mouth opening, headaches) were complained by 92.5% of SSc patients and by 76.2% of controls (χ² 8.012 p 0.005).[ncbi.nlm.nih.gov] 8,17,45,46 Involvement of the posterior segment of the eye is often subclinical. 6,7 Reported ophthal moscopic findings in patients with SSc include microvas cular changes, cotton-wool[scielo.br] Monitoring should include regular blood pressure monitoring (both at home and in clinic), complete blood counts, creatinine and urinalysis (assessing for hematuria and proteinuria[clinicaladvisor.com]

  • Retinopathy

    Some patients might report reduced vision or headaches.[symptoma.com] An ocular examination revealed multiple retinal cotton-wool spots and hard exudates. Interferon treatment was suspended.[ncbi.nlm.nih.gov] Renal disease, as evidenced by proteinuria and elevated blood urea nitrogen (BUN)/creatinine levels, is an excellent predictor of retinopathy; both conditions are caused by[emedicine.medscape.com]

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