Cranial Asymmetry: Causes & Reasons

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Possible Causes for Cranial Asymmetry

Brachycephaly

The authors conclude that orthotic therapy is a safe and effective therapeutic modality for position cranial asymmetries. [ncbi.nlm.nih.gov]

Other studies have already showed major decreases in the value of the cranial asymmetry index with orthesis treatment. [scielo.br]

BACKGROUND: Positional plagiocephaly is the most common cause of cranial asymmetry. [ncbi.nlm.nih.gov]

Wolf-Hirschhorn Syndrome

asymmetry Droopy eyelids Dental abnormalities DImple at the base of spine Aside from the possibly physical properties due to Wolf-Hirschhorn syndrome, patients diagnosed [wiki.ggc.edu]

Heart problems Underdeveloped bones of the head and pelvis Cranial asymmetry Malformation of the organs of the urinary system Malformation of bones in chest and spine Distinctive [medicalsubstance.com]

[wolfhirschhorn.org] Musculoskeletal Cranial Asymmetry Heart problems Underdeveloped bones of the head and pelvis Cranial asymmetry Malformation of the organs of the urinary [symptoma.com]

Acrocephalopolysyndactyly

asymmetry). [rarediseases.org]

Systemic Features: Premature synostosis involves numerous cranial sutures with the sagittal suture commonly involved causing acrocephaly (tower skull). [disorders.eyes.arizona.edu]

In addition, the cranial sutures often fuse unevenly, causing the head and face to appear dissimilar from one side to the other (craniofacial asymmetry). [rarediseases.org]

Craniosynostosis

The adverse effects associated with surgical correction of craniosynostosis include cerebrospinal fluid leak, injury to the brain, wound healing problems, cranial asymmetry [clinicaladvisor.com]

Since the early 1990s, US pediatricians have seen an increase in the number of children with cranial asymmetry, particularly unilateral flattening of the occiput, likely attributable [pediatrics.aappublications.org]

asymmetry sleep positioning SIDS Back to Sleep tummy time INTRODUCTION Flattening of the occiput and asymmetrical skull molding may be caused by mechanical factors that act [pediatrics.aappublications.org]

Saethre-Chotzen Syndrome

The features of the syndrome include: turriplagiocephaly with a cranial circumference of 52 cm, facial asymmetry, low hairline, proptosis, antimongoloid slanting of palpebral [ncbi.nlm.nih.gov]

Generally it is accepted that individuals should undergo a cranioplasty within the first year of life; this helps prevent progressive facial asymmetry, increased inter-cranial [wiki.ggc.usg.edu]

Opitz G/BBB Syndrome Type 2

asymmetry 0000267 Cryptorchidism Undescended testes Undescended testis [ more ] 0000028 Depressed nasal bridge Depressed bridge of nose Flat bridge of nose Flat nasal bridge [rarediseases.info.nih.gov]

Coarctation of aorta Narrowing of aorta Narrowing of the aorta [ more ] 0001680 Conductive hearing impairment Conductive deafness Conductive hearing loss [ more ] 0000405 Cranial [rarediseases.info.nih.gov]

Crouzon Syndrome

Despite presence of clinical features of cranial and facial asymmetry, frontal bossing, hypertelorism, recurrent eye infections, restricted neck movements and abnormal changes [omicsonline.org]

The patient’s neurological examination revealed early signs of quadriparesis and was immediately taken up for posterior cranial fossa decompression surgery. [omicsonline.org]

When investigated thoroughly the case was identified as an undiagnosed case of Crouzon syndrome with Arnold Chiari Type I malformation with syringomyelia and asymmetry of [omicsonline.org]

Freeman-Sheldon Syndrome

Freeman-Sheldon syndrome (FSS), also known as distal arthrogryposis type 2A, whistling-face syndrome, or windmill vane hand syndrome, is a rare genetic disorder which has been reported with both autosomal dominant and autosomal recessive inheritance patterns. Most cases, however, occur sporadically as a[…] [symptoma.com]

Schimmelpenning-Feuerstein-Mims Syndrome

Abdominal Pregnancy

asymmetry, limb defects or deficits of the central nervous system (CNS) are most common, with oligohydramnios being the presumably pathogenic mechanism. [symptoma.com]

The infant’s head circumference was 40cm (5th centile); the cranial asymmetry was barely noticeable. [doi.org]

The most common deformations observed were facial and/or cranial asymmetry and various joint abnormalities. [doi.org]

Craniosynostosis Type 3

Cranial vault asymmetry index (CVAI) and cranial index (CI) were calculated and analyzed using a descriptive statistical general linear model. [search.pedro.org.au]

[…] vault asymmetry and index. [clinicaltrials.gov]

The most significant measurements used in this initial evaluation are skull base asymmetry, cranial vault asymmetry, orbitotragial depth, and cephalic index. [aetna.com]

Isolated Synostotic Plagiocephaly

The use of computed tomography (CT) imaging is only indicated in case of an ISP suspicion, particularly if infant repositioning does not improve cranial asymmetry over weeks [symptoma.com]

Neurosurgery 1980;6:39-44 Lohse DC, et al: Cranial asymmetry and lambdoid synostosis in a sibship. [skullbaseinstitute.com]

The most significant measurements used in this initial evaluation are skull base asymmetry, cranial vault asymmetry, orbitotragial depth, and cephalic index. [aetna.com]

Oculopalatoskeletal Syndrome

There was also spina bifida occulta, radioulnar synostosis and cranial asymmetry. Two of the sibs had lambdoidal craniosynostosis. [fdna.health]

Sometimes other skeletal defects in the form of spina bifida occulta, cranial asymmetry, abnormality of the occipital bone in addition to micrognathia are found. [1], [4], [ijo.in]

Congenital Malformation Syndromes Involving Early Overgrowth

asymmetry * Bulbous nose * Long philtrum * Nasal stenosis * Small mouth * Down turned corners of mouth * Midline in lower ip * Highly arched palate * Asymmetrical thorax [checkorphan.org]

asymmetry Cognitive impairment Atrial septal defect Spina bifida occulta Ventricular septal defect Abnormality of the skeletal system Hernia Pes planus Coloboma Renal cyst [mendelian.co]

Craniosynostosis * Low set ears * Cupped ears * Downward slanting space between eyelids * Blepharophimosis * Turricephaly * Small jaw * Retrognathia * Sloping forehead * Cranial [checkorphan.org]

Lambdoid Synostosis

Cranial asymmetry in the absence of synostosis of the sutures and involving the occiput is described in the literature as nonsynostotic posterior plagiocephaly. www.wordscope.com [wordscope.com]

Partial Monosomy 7p

asymmetry). [rarediseases.org]

In addition, in some instances, craniosynostosis, particularly that involving two or more cranial sutures, may lead to certain neurologic complications. [rarediseases.org]

[…] small head (microcephaly), widely spaced eyes (ocular hypertelorism), and/or other findings; the skull may also appear relatively dissimilar from one side to the other (cranial [rarediseases.org]

Dolichocephaly

Treatment generally takes 3–4 months, but varies depending on the infant’s age and severity of cranial asymmetry. [orthomerica.com]

X-Linked Mandibulofacial Dysostosis

asymmetry, ptosis, malformed ears UNK DiGeorge syndrome chromosome region CATCH22 22q11 188400 DiGeorge syndrome 188400 AD low-set ears, short ears, small mouth, submucous [widesmiles2.org]

[…] malformed ears TF Twist TWIST 7p21 601622 Saethre-Chotzen syndrome 101400 AD craniosynostosis, acrocephaly, brachycephaly, flat facies, thin long pointed nose, cleft palate, cranial [widesmiles2.org]

Humeroradial Synostosis with Craniofacial Anomalies

Craniosynostosis with cranial asymmetry, skeletal defects, hearing deficit, cleft lip and palate, and mild mental retardation; hydronephrosis is described. [accesspediatrics.mhmedical.com]

Occasional presence of spinal bifida occulta, cranial asymmetry, occipital bone flattening, and cleft lip/palate. Patient may manifest psychological development delays. [accesspediatrics.mhmedical.com]

Disorder of Manganese Transport

Via whole-exome sequencing, we studied a child that presented with cranial asymmetry, severe infantile spasms with hypsarrhythmia, and dysproportionate dwarfism. [uniprot.org]

Craniosynostosis Type 4

Most children with cranial asymmetry simply have positional plagiocephaly. [nicklauschildrens.org]

asymmetry and lambdoid synostosis in a sibship. ( 4010909 ) Lohse D.C....Ment L.R. 1985 43 Lambdoid synostosis. [malacards.org]

Neurosurgery 1980;6:39-44 Lohse DC, et al: Cranial asymmetry and lambdoid synostosis in a sibship. [skullbaseinstitute.com]

Collins-Sakati-Nyhan Syndrome

Amblyopia and optic atrophy again contribute to visual loss in these patients.32 Patients with plagiocephaly exhibit a cranial asymmetry caused by a premature closure of the [entokey.com]

Coronal synostosis, hypertelorism, epicanthal folds, radial aplasia, absent carpal bones, autosomal recessive Saethre-Chotzen syndrome is characterized by a more variable cranial [entokey.com]

Other features include low-set frontal hairline, facial asymmetry, variable brachydactyly and syndactyly, low-set ears, hearing loss, highly arched palate, and dental abnormalities [entokey.com]

Skull Fracture

Early recognition and surgical repair is essential to prevent the development of neurological complications and cranial asymmetry. [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

BACKGROUND: Growing skull fracture (GSF) is a rare complication of pediatric skull fractures and causes delayed-onset neurological deficits and cranial asymmetry. [ncbi.nlm.nih.gov]

Untreated GSFs may cause delayed-onset neurological manifestations in addition to cranial growth asymmetry. These enormous-sized GSFs may be difficult to treat. [ncbi.nlm.nih.gov]

Autosomal Dominant Mandibulofacial Dysostosis with Ptosis

asymmetry, ptosis, malformed ears UNK DiGeorge syndrome chromosome region CATCH22 22q11 188400 DiGeorge syndrome 188400 AD low-set ears, short ears, small mouth, submucous [widesmiles2.org]

There were no palpable cranial defects. Hands and feet were normal. [docslide.us]

Isolated Arhinencephaly

Cranial asymmetry is the first clinical sign usually present at birth; in the most severe cases,... [connection.ebscohost.com]

Hemimegalencephaly

Cranial asymmetry is the first clinical sign usually present at birth; in the most severe cases, hemimegalencephaly may be evident during pregnancy. [ncbi.nlm.nih.gov]

asymmetry, hemiparesis, epilepsy, and mental retardation. [jpatholtm.org]

Cranial asymmetry and central nervous system manifestations (generalized seizures, hemimegalencephaly, dysgenesis of the corpus callosum and neuronal migration defects) have [orpha.net]

Microcephaly

The diagnostic workup of the first patient revealed congenital cranial bone asymmetry and molding, and the second patient's workup revealed cranial molding. [ncbi.nlm.nih.gov]

Transient craniofacial asymmetries and cranial molding can mimic congenital microcephaly caused by brain abnormalities or neurotropic infectious pathogens, including Zika. [ncbi.nlm.nih.gov]

Clinical exclusion of transient congenital craniofacial asymmetries and cranial molding could be a cost-effective first step in the diagnostic workup of microcephaly. [ncbi.nlm.nih.gov]

Nevus Sebaceous

Abnormalities of the toes 0001780 Basal cell carcinoma 0002671 Coarctation of aorta Narrowing of aorta Narrowing of the aorta [ more ] 0001680 Coloboma Notched pupil 0000589 Cranial [rarediseases.info.nih.gov]

asymmetry 0000267 Hemangioma Strawberry mark 0001028 Hemihypertrophy Asymmetric overgrowth 0001528 Hemimegalencephaly 0007206 Horseshoe kidney Horseshoe kidneys 0000085 Hypophosphatemic [rarediseases.info.nih.gov]

Congenital Muscular Torticollis

Diagnosis of plagiocephaly or other cranial asymmetries is based on clinical observation by the child's healthcare professional. [hss.edu]

Incidence of cranial asymmetry in health newborns. Pediatrics. 2002;110(6). 119. Golden KA, Beals SP, Littlefield TR, Pomatto JK. [journals.lww.com]

Plagiocephaly : Cranial asymmetry with flattening of 1 side of the head. 121 Sternocleidomastoid mass (synonymous with fibromatosis colli, tumor, pseudotumor, or node): A [journals.lww.com]

CLOVES Syndrome

[…] hyperostosis 0004437 Facial asymmetry Asymmetry of face Crooked face Unsymmetrical face [ more ] 0000324 Macrodactyly Finger overgrowth 0004099 Overgrowth General overgrowth [rarediseases.info.nih.gov]

0008678 Scoliosis 0002650 Spinal dysraphism 0010301 Tethered cord 0002144 Percent of people who have these symptoms is not available through HPO Capillary malformation 0025104 Cranial [rarediseases.info.nih.gov]