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45 Possible Causes for Cranial Nerve Involvement, Descending Paralysis, Myasthenia Gravis

  • Botulism

    INTRODUCTION: Clostridium botulinum is known to cause descending paralysis in infants throughout the world.[ncbi.nlm.nih.gov] Findings that distinguish botulism from myasthenia gravis: nausea/vomiting, poorly reactive pupils, and paralysis of accommodation. [Purvin V, Kawasaki A.[web.archive.org] The PNS can also be affected leading to cranial nerve involvement, focal or multifocal neuropathies, and dysfunction of the autonomic nervous system.[ncbi.nlm.nih.gov]

  • Guillain-Barré Syndrome

    For example, in 1986, Ropper described patients who developed rapidly progressive oropharyngeal, neck and shoulder weakness that mimicked the descending paralysis seen in[vdocuments.net] Many neurologists are unfamiliar with PCB, which is often misdiagnosed as brainstem stroke, myasthenia gravis or botulism.[ncbi.nlm.nih.gov] Clinical dysphagia was observed in seven patients and six of these cases involved a lower cranial nerve while five patients without cranial nerve involvement had silent dysphagia[ncbi.nlm.nih.gov]

  • Wound Botulism

    Wound botulism in 7 heroin 'skin poppers' produced ophthalmoplegia and descending paralysis.[ncbi.nlm.nih.gov] Wound botulism may be underdiagnosed because of confusion with inflammatory neuropathy or myasthenia gravis.[ncbi.nlm.nih.gov] RESULTS: Clinical data were available in 11 (92%) of 12 patients; in 7 (58%) of the 12 cases, there was cranial nerve involvement including mydriasis, diplopia, dysarthria[ncbi.nlm.nih.gov]

  • Infantile Botulism

    Note that, in many cases, descending paralysis may be absent.[symptoma.com] gravis and other myoneural disorders 2016 2017 2018 2019 Non-Billable/Non-Specific Code Diagnosis Index entries containing back-references to A48.51 : Botulism (foodborne[icd10data.com] gravis Once definite evidence of botulism is found with laboratory tests, usually no additional testing is needed.[drugs.com]

  • Miller-Fisher Syndrome

    Abstract BACKGROUND: Miller Fisher syndrome (MFS) is a rare demyelinating condition which may have involvement of cranial nerves.[ncbi.nlm.nih.gov] As mentioned earlier, descending paralysis is a characteristic manifestation of Miller Fisher syndrome.[buzzle.com] A provisional diagnosis of ocular myasthenia gravis was made, and anticholinesterase inhibitor therapy was initiated.[ncbi.nlm.nih.gov]

  • Tick Paralysis

    […] that the acute ascending or rare descending type of paralysis originally described by Landry is simply a form of poliomyelitis, whereas others contend that Landry's paralysis[annals.org] gravis.[ncbi.nlm.nih.gov] If the tick continues to feed, the weakness ascends to the upper extremities over a matter of hours, followed by cranial nerve involvement.[ncbi.nlm.nih.gov]

  • Deliberate Exposure to Botulinum Toxin

    Conclusions: An aerosolized or foodborne botulinum toxin weapon would cause acute symmetric, descending flaccid paralysis with prominent bulbar palsies such as diplopia, dysarthria[experts.umn.edu] Differential diagnoses include Guillian-Barre syndrome and its Miller Fisher variant, organophosphate poisoning, and myasthenia gravis.[icmcasesummaries.com] It presents with an afebrile, descending, symmetrical, flaccid paralysis of motor and autonomic but not sensory nerves.[emj.bmj.com]

  • Brain Stem Disorder

    […] of face, arm, and leg: Corticobulbar and corticospinal tract descending in crus cerebri 16.[slideshare.net] Myasthenia gravis. Orphanet J Rare Dis 2007;2:44. 67. Vincent A, Newsom Davis J. Anti-acetylcholine receptor antibodies.[neuroophthalmology.ca] Clinically, in localizing strokes to the brainstem one looks for the "cardinal" feature of an ipsilateral peripheral cranial nerve involvement, and a contralateral weakness[tchain.com]

  • Accessory Nerve Palsy

    Cranial nerves may be affected singly or in groups and knowledge of which nerves are involved helps locate the lesion.[patient.info] Related Articles Top 5 Articles From October 2015 An Unusual Case of Descending Paralysis Caused by West Nile Virus Clinicians should consider a diagnosis of West Nile Virus[practicalneurology.com] Examples of neuromuscular disorders include Amyotrophic lateral sclerosis Multiple sclerosis Myasthenia gravis Spinal muscular atrophy Many neuromuscular diseases are genetic[icdlist.com]

  • Progressive Bulbar Palsy

    Clinicians frequently think of the symptoms of botulism in terms of a classic triad: bulbar palsy and descending paralysis, lack of fever, and clear senses and mental status[diki.pl] How many people are affected by myasthenia gravis each year? Who are most affected by myasthenia graivs? Younger women and older men[quizlet.com] Electrodiagnostic tests MRI of the brain and, if no cranial nerve involvement, cervical spine Laboratory tests to check for other, treatable causes Diagnosis of motor neuron[merckmanuals.com]

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