Creatine Phosphokinase Increased: Causes & Reasons

Possible Causes for Creatine Phosphokinase Increased

High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine [rarediseases.info.nih.gov]

[…] kinase Elevated blood creatine phosphokinase Elevated circulating creatine phosphokinase Elevated creatine kinase Elevated serum CPK Elevated serum creatine phosphokinase [rarediseases.info.nih.gov]

phosphokinase [ more ] 0003236 EMG abnormality 0003457 Feeding difficulties in infancy 0008872 Flexion contracture Flexed joint that cannot be straightened 0001371 Gait disturbance [rarediseases.info.nih.gov]

Congenital Muscular Dystrophy Type 1A

phosphokinase Elevated blood creatine phosphokinase Elevated circulating creatine phosphokinase Elevated creatine kinase Elevated serum CPK Elevated serum creatine kinase [rarediseases.info.nih.gov]

[…] serum concentration of creatine phosphokinase (CK), myoglobinuria, and occasional muscle cramps. [news-medical.net]

Limb-Girdle Muscular Dystrophy Type 2A

phosphokinase [ more ] 0003236 Hamstring contractures 0003089 Hyperlordosis Prominent swayback 0003307 Lower limb muscle weakness Lower extremity weakness Lower limb weakness [rarediseases.info.nih.gov]

Strychnine Poisoning

Our patient survived, even though at one point he had a pH of 6.55, a lactate level of 32 mM/liter, a temperature of 43 degrees C, and rhabdomyolysis with an increased creatine [ncbi.nlm.nih.gov]

phosphokinase level of 359,000 mU/ml (5,983 mumol/s/liter). [ncbi.nlm.nih.gov]

McArdle Disease

creatine kinase Elevated serum CPK Elevated serum creatine phosphokinase High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase [rarediseases.info.nih.gov]

Increased serum CK Increased serum creatine kinase Increased serum creatine phosphokinase [ more ] 0003236 30%-79% of people have these symptoms Myopathy Muscle tissue disease [rarediseases.info.nih.gov]

Showing of 12 | 80%-99% of people have these symptoms Elevated serum creatine kinase Elevated blood creatine phosphokinase Elevated circulating creatine phosphokinase Elevated [rarediseases.info.nih.gov]

Rhabdomyolysis

[…] with common exertional activities (e.g. >20x normal at 1 day after marathon) See Creatine Phosphokinase Myoglobin level increased Increased in urine or serum, but has lower [fpnotebook.com]

creatine phosphokinase, myoglobin, lactate dehydrogenase, serum aspartate aminotransferase, hypercholesterolemia, and a basal serum prolactin near the upper limit of normal [ncbi.nlm.nih.gov]

[…] muscle fibers Release of muscle fiber contents into circulation Myoglobin Potassium (risk of Hyperkalemia ) Calcium (risk of Hypercalcemia ) Phosphate Creatine Phosphokinase [fpnotebook.com]

Becker Muscular Dystrophy

Background The dystrophinopathies include a spectrum of muscle diseases The mild end of the spectrum includes asymptomatic increases in serum concentration of creatine phosphokinase [bcidaho.com]

Miyoshi Myopathy Type 1

phosphokinase [ more ] 0003236 Lower limb muscle weakness Lower extremity weakness Lower limb weakness Muscle weakness in lower limbs [ more ] 0007340 Muscle fibrillation [rarediseases.info.nih.gov]

Autosomal Recessive Inclusion Body Myopathy Type 2

phosphokinase [ more ] 0003236 Gait disturbance Abnormal gait Abnormal walk Impaired gait [ more ] 0001288 Showing of 31 | Last updated: 5/1/2019 Inclusion body myopathy [rarediseases.info.nih.gov]

Malignant Hyperthermia

CVVH was employed when the values of creatine phosphokinase (CPK), myoglobin (Mb), and lactate dehydrogenase (LDH) increased significantly. [ncbi.nlm.nih.gov]

[…] in core body temperature Grossly elevated blood levels of creatine phosphokinase and myoglobin Dark urine (myoglobinuria) Severe cardiac arrhythmia and cardiac arrest Disseminated [revonto.com]

Stroke

Interestingly, creatine phosphokinase increased after l-carnitine was stopped, indicating that l-carnitine had helped to reduce muscle damage during rehabilitation. [ncbi.nlm.nih.gov]

Apical Myocardial Infarction

Creatine phosphokinase was maximal at 1073mg/dL the next day. [ncbi.nlm.nih.gov]

A Tc-pyrophosphate cardiac scintigram revealed an increased uptake of the radioisotope localized at the left ventricular apex. [ncbi.nlm.nih.gov]

Status Epilepticus

phosphokinase, and increased serum triglycerides are markers of propofol infusion syndrome and should be monitored carefully. [bcmj.org]

The infusion rate should not exceed 4 mg/kg/h; if seizure control is not achieved rapidly, another agent should be used.[33] Acid-base imbalance, increased serum creatine [bcmj.org]

The infusion rate should not exceed 4 mg/kg/h; if seizure control is not achieved rapidly, another agent should be used.[ 33 ] Acid-base imbalance, increased serum creatine [bcmj.org]

Limb-Girdle Muscular Dystrophy

We present a 19-year-old girl with epilepsy and elevated creatine phosphokinase (CPK) concentration. [ncbi.nlm.nih.gov]

Due to increased CPK, myopathy was suspected and muscle biopsy was performed. [ncbi.nlm.nih.gov]

Dermatomyositis

Elevated creatine phosphokinase increases the suspicion of an inflammatory muscle disease, and muscle biopsy is the definitive diagnostic tool for inflammatory myopathies. [rc.rcjournal.com]

Creatine phosphokinase (CPK) was increased at 1,319U/L (normal Human Immunodeficiency Virus 1 and 2 antibodies, Epstein-Barr virus and cytomegalovirus antigenaemia. [revistanefrologia.com]

Patients often have many lab abnormalities that are seen in classic dermatomyositis though creatine phosphokinase and myoglobin levels are more likely to be normal given the [stanfordmedicine25.stanford.edu]

Haff Syndrome

Baseline complete blood count and chemistries were normal, but serum creatine phosphokinase (CPK) was highly increased (Table 1). [apjmt.mums.ac.ir]

In the occurrence of suspected cases, it is recommended to test for creatine phosphokinase (CPK) or OGT to observe the increase of muscle enzymes. [flutrackers.com]

Muscular Dystrophy

creatine phosphokinase (CpK3), electromyography, and genetic testing. [en.wikipedia.org]

[…] and flexible subnetworks having molecular functions involved with calcium.[8] Diagnosis[edit] The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased [en.wikipedia.org]

Secondary Myopathy

Cirioni O, Weimer LE, Fragola V, et al.(2013) Sustained Increase of Serum Creatine Phosphokinase Levels and Progressive Muscle Abnormalities Associated with Raltegravir use [hiv.imedpub.com]

Tropical Myositis

Muscle enzymes (aldolase, creatine phosphokinase, aminotransferase, and lactic dehygrogenase) are usually normal or slightly raised. [dermnetnz.org]

Interestingly, creatine phosphokinase and aldolase levels is found to be normal in pyomyositis [ 1, 11 ]. [panafrican-med-journal.com]

Ultrasound scan shows hypoechoic areas with an increase in muscle mass and collection of fluid. [dermnetnz.org]

Myopathy

The laboratory evaluation was remarkable for the marked increase in the serum lactate dehydrogenase and creatine phosphokinase levels. [ncbi.nlm.nih.gov]

Cirioni O, Weimer LE, Fragola V, et al.(2013) Sustained Increase of Serum Creatine Phosphokinase Levels and Progressive Muscle Abnormalities Associated with Raltegravir use [hiv.imedpub.com]

Myoadenylate Deaminase Deficiency

phosphokinase, hypoketotic hypoglycemia, and increased lipid in muscle. [rheumaknowledgy.com]

Some, but not all, metabolic myopathies are associated with elevated creatine phosphokinase levels; normal values do not exclude these disorders. [rheumaknowledgy.com]

Muscle weakness begins in childhood and may be associated with myalgias, proximal weakness, respiratory muscle weakness, cardiomyopathy, myoglobinuria, increased creatine [rheumaknowledgy.com]

Congenital Muscular Dystrophy

The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased creatine phosphokinase (CpK3), electromyography, and genetic testing. [en.wikipedia.org]

The laboratory investigations displayed an increased level of serum creatine phosphokinase (CK) present since the neonatal period and persisting elevated in all children with [doi.org]

Myotonia permanens

Biochemical analyses showed slight increase in creatine phosphokinase at 404 UI/l (normal < 200 UI/l), normal blood level of potassium and sodium per crises and post crises [jmhg.springeropen.com]

Diabetic Ketotic Coma

Dehydration also can lead to increases in total serum protein, albumin and creatine phosphokinase concentration in patients with acute diabetic decompensation. [endocrinologyadvisor.com]

Traumatic Rhabdomyolysis

Among these, an increased serum creatine phosphokinase by more than 5-fold the upper normal limit is an important diagnostic parameter [ 48–50 ]. [ckj.oxfordjournals.org]

A dirty-brownish discolouration of the urine as a result of myoglobinuria and increased serum levels of substances released from the injured muscles such as creatinine, phosphate [ckj.oxfordjournals.org]

Myocardial Contusion

phosphokinase (CPK) in 39 patients, and positive CPK-Muscle Brain (CPK-MB) isoenzyme in 33 patients. [ncbi.nlm.nih.gov]

[…] months, 42 patients with blunt chest trauma were diagnosed as having a myocardial contusion on the basis of an abnormal electrocardiogram (ECG) in 36 patients, elevated creatine [ncbi.nlm.nih.gov]

Using these screening modalities, the incidence of myocardial contusion in patients with blunt chest trauma increased from 7 per cent when viewed retrospectively to 17 per [ncbi.nlm.nih.gov]

Polymyositis

There was increased proximal muscle strength and reduction in the creatine phosphokinase level. [rheumatology.oxfordjournals.org]

In five patients with refractory juvenile dermatomyositis, muscle strength increased and creatine phosphokinase levels decreased with combination therapy. [rheumatology.oxfordjournals.org]

Myotonia Congenita

Weil Disease

He had elevated blood urea nitrogen, creatine phosphokinase and serum glutamic-oxaloacetic transaminase. [ncbi.nlm.nih.gov]

During the first 6 days of this undiagnosed illness azotemia increased, a pericardial friction rub occurred, and hematuria was present. [ncbi.nlm.nih.gov]

Paramyotonia Congenita

Laboratory examinations revealed elevated serum creatine phosphokinase (810 IU/I; normal range 0-150). [ci.nii.ac.jp]

Administration of KCl (5g) resulted in an increase of plasma potassium concentration (from 3.5 to 4.5 mEq/ l ), and aggravation of the muscle stiffness and weakness was observed [ci.nii.ac.jp]