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12 Possible Causes for Creatine Phosphokinase Increased, Difficulty Rising from a Squatting Position

  • Secondary Myopathy

    Cirioni O, Weimer LE, Fragola V, et al.(2013) Sustained Increase of Serum Creatine Phosphokinase Levels and Progressive Muscle Abnormalities Associated with Raltegravir use[hiv.imedpub.com] Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] […] up from a squatted position, climbing stairs.[sites.google.com]

  • Dermatomyositis

    Elevated creatine phosphokinase increases the suspicion of an inflammatory muscle disease, and muscle biopsy is the definitive diagnostic tool for inflammatory myopathies.[rc.rcjournal.com] Patients may have difficulty rising from a chair or squatting and then raising themselves from this position.[emedicine.medscape.com] Creatine phosphokinase (CPK) was increased at 1,319U/L (normal Human Immunodeficiency Virus 1 and 2 antibodies, Epstein-Barr virus and cytomegalovirus antigenaemia.[revistanefrologia.com]

  • Inclusion Body Myositis

    The most common reasons for presentation are related to weakness of the quadriceps muscles, such as difficulty rising from low chairs or from the squatting or kneeling positions[ibmmyositis.com] phosphokinase (CPK) and inflammatory cell infiltration.[emedicine.medscape.com] Posttreatment muscle biopsy samples showed increased vacuole formation and amyloid deposition, suggesting that mechanisms other than the inflammatory response play a role[emedicine.medscape.com]

  • Myoadenylate Deaminase Deficiency

    Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] phosphokinase, hypoketotic hypoglycemia, and increased lipid in muscle.[rheumaknowledgy.com] […] up from a squatted position, climbing stairs.[sites.google.com]

  • Myoglobinuria

    Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] creatine phosphokinase (CK) in serum and appearance of small amounts of myoglobin in the urine, but without clinical symptoms.[ncbi.nlm.nih.gov] […] with common exertional activities (e.g. 20x normal at 1 day after marathon) See Creatine Phosphokinase Myoglobin level increased Increased in urine or serum, but has lower[fpnotebook.com]

  • Distal Myopathy Type 3

    High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased creatine phosphokinase (CpK3), electromyography, and genetic testing.[en.wikipedia.org]

  • Myopathic Carnitine Deficiency

    Muscle enzymes were still greatly increased: creatine phosphokinase 720 U/l (normal A biopsy of the left deltoid muscle disclosed severe necrotising myopathy with pronounced[jnnp.bmj.com] rising from squatting position, getting up from chair •tender muscles to pressure •can progress rapidly with complications such as dysphagia and aspiration pneumonia •skin[quizlet.com] […] polymyositis and dermatomyositis •humoral factors in dematomysositis, cellular in polymyositis Clinics •fatigue, myalgia, joint pain •symmetrical, proximal muscle weakness -difficulty[quizlet.com]

  • Distal Myopathy

    The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased creatine phosphokinase (CpK3), electromyography, and genetic testing.[en.wikipedia.org] Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] Dystrophinopathies include a spectrum of muscle diseases ranging from asymptomatic with an increase in serum concentration of creatine phosphokinase to the severe progressive[blueprintgenetics.com]

  • Inclusion Body Myopathy

    High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] The most common reasons for presentation are related to weakness of the quadriceps muscles, such as difficulty rising from low chairs or from the squatting or kneeling positions[ibmmyositis.com] phosphokinase 32 hallmark (90%) HP:0003236 22 hyperlordosis 32 hallmark (90%) HP:0003307 23 sensory axonal neuropathy 32 occasional (7.5%) HP:0003390 24 emg 32 occasional[malacards.org]

  • Autosomal Dominant Myoglobinuria

    […] with common exertional activities (e.g. 20x normal at 1 day after marathon) See Creatine Phosphokinase Myoglobin level increased Increased in urine or serum, but has lower[fpnotebook.com] Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] […] muscle fibers Release of muscle fiber contents into circulation Myoglobin Potassium (risk of Hyperkalemia ) Calcium (risk of Hypercalcemia ) Phosphate Creatine Phosphokinase[fpnotebook.com]

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