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1,046 Possible Causes for Creatine Phosphokinase Increased, EMG Shows Evidence of Reinnervation, Muscle Biopsy Abnormal

  • Muscular Dystrophy

    This condition is typically characterized by large and abnormally distributed mitochondria on muscle biopsy, which can distinguish this condition from the other muscle conditions[ncbi.nlm.nih.gov] The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased creatine phosphokinase (CpK3), electromyography, and genetic testing.[en.wikipedia.org] Under the microscope, the muscle of a positive biopsy generally shows dead tissue and abnormally large muscle fibers.[cedars-sinai.edu]

    Missing: EMG Shows Evidence of Reinnervation
  • Duchenne Muscular Dystrophy

    Diagnosis of Duchenne Muscular Dystrophy A muscle biopsy (taking a sample of muscle) for dystrophin studies can be done to look for abnormal levels of dystrophin in the muscle[disabled-world.com] […] fibers) For Duchenne and Becker muscular dystrophies, muscle biopsy may show whether dystrophin, a muscle protein, is missing or abnormal, and DNA testing is used to analyze[webmd.com] A muscle biopsy (taking a sample of muscle) for dystrophin studies can be done to look for abnormal levels of dystrophin in the muscle.[genome.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Becker Muscular Dystrophy

    Electromyography was abnormal in all patients. Muscle biopsy in 1 patient demonstrated normal immunostaining for dystrophin.[ncbi.nlm.nih.gov] High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] Elevated serum CK Skeletal muscle biopsy showing decreased dystrophin quantity Panel overlap The gene on this panel is also included on our Autism Intellectual Disability[unmc.edu]

    Missing: EMG Shows Evidence of Reinnervation
  • Polymyositis

    Muscle biopsy abnormalities at some time during their disease: i. degeneration and regeneration of muscle fibers ii. necrosis iii. phagocytosis iv. interstitial mononuclear[clinicaltrials.gov] There was increased proximal muscle strength and reduction in the creatine phosphokinase level.[rheumatology.oxfordjournals.org] Laboratory testing showed elevated muscle enzymes and myopathic abnormalities on electromyographic examination.[ncbi.nlm.nih.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Tropical Myositis

    The serum creatine kinase (CK) level was high (1370 U/L; RR, A biopsy of the quadriceps showed the muscle to be pale, flaccid and atrophic.[mja.com.au] Muscle enzymes (aldolase, creatine phosphokinase, aminotransferase, and lactic dehygrogenase) are usually normal or slightly raised.[dermnetnz.org] Interestingly, creatine phosphokinase and aldolase levels is found to be normal in pyomyositis [ 1, 11 ].[panafrican-med-journal.com]

    Missing: EMG Shows Evidence of Reinnervation
  • Limb-Girdle Muscular Dystrophy

    Muscle biopsy abnormalities in two individuals very early in the course of their disease suggest that biopsy would probably be useful in detection of preclinical disease in[pediatrics.aappublications.org] We present a 19-year-old girl with epilepsy and elevated creatine phosphokinase (CPK) concentration.[ncbi.nlm.nih.gov] Some LGMD subtypes have distinguishing features, including pattern of muscle involvement, cardiac abnormalities, extramuscular involvement, and muscle biopsy findings.[ncbi.nlm.nih.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Dermatomyositis

    Muscle biopsy abnormalities at some time during their disease: i. degeneration and regeneration of muscle fibers ii. necrosis iii. phagocytosis iv. interstitial mononuclear[clinicaltrials.gov] Elevated creatine phosphokinase increases the suspicion of an inflammatory muscle disease, and muscle biopsy is the definitive diagnostic tool for inflammatory myopathies.[rc.rcjournal.com] Creatine phosphokinase (CPK) was increased at 1,319U/L (normal Human Immunodeficiency Virus 1 and 2 antibodies, Epstein-Barr virus and cytomegalovirus antigenaemia.[revistanefrologia.com]

    Missing: EMG Shows Evidence of Reinnervation
  • Amyotrophic Lateral Sclerosis

    Only about 10% of ALS patients have abnormal nerve conduction study results, but the test can also suggest other diagnoses. A muscle biopsy.[webmd.com]

    Missing: EMG Shows Evidence of Reinnervation
  • Myopathy

    Clinical presentation, abnormal secretion of the collagen demonstrated in muscle biopsy and the COL6A1 c.1056 3A C mutation justify classification of the presented case as[ncbi.nlm.nih.gov] The laboratory evaluation was remarkable for the marked increase in the serum lactate dehydrogenase and creatine phosphokinase levels.[ncbi.nlm.nih.gov] Laing early onset distal myopathy: slow myosin defect with variable abnormalities on muscle biopsy. J Neurol Neurosurg Psychiatry. 2006;77:208-15.[rarediseases.org]

    Missing: EMG Shows Evidence of Reinnervation
  • Inclusion Body Myositis

    Muscle biopsy may display several common findings including; inflammatory cells invading muscle cells, vacuolar degeneration, inclusions or plaques of abnormal proteins.[phoenixstemcelltreatmentcenter.com] phosphokinase (CPK) and inflammatory cell infiltration.[emedicine.medscape.com] Muscle biopsy may display several common findings including; inflammatory cells invading muscle cells, vacuolar degeneration, inclusions or plaques of abnormal proteins. sIBM[en.wikipedia.org]

    Missing: EMG Shows Evidence of Reinnervation