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40 Possible Causes for Creatine Phosphokinase Increased, Facial Muscle Weakness and Progressive Atrophy

  • Muscular Dystrophy

    Abstract Facioscapulohumeral muscular dystrophy is an autosomal-dominant, slowly progressive myopathy that involves facial, shoulder, and upper arm muscles.[ncbi.nlm.nih.gov] The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased creatine phosphokinase (CpK3), electromyography, and genetic testing.[en.wikipedia.org] Facial muscle atrophy and weakness leads to drooping of the lower lip, which has unfavorable functional and aesthetic outcomes.[ncbi.nlm.nih.gov]

  • Progressive Muscular Atrophy

    Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] Progressive bulbar palsy, also called progressive bulbar atrophy, involves the brain stem—the bulb-shaped region containing lower motor neurons needed for swallowing, speaking[web.archive.org]

  • Limb-Girdle Muscular Dystrophy Type 2A

    There is often asymmetric quadriceps, hamstring, biceps, brachioradialis, or calf weakness and atrophy. Muscle pain is common.[emedicine.medscape.com] High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] Facial weakness, hand weakness, and contractures are uncommon. Progression is slow, and walking is retained. Cardiac and respiratory function is normal.[emedicine.medscape.com]

  • Amyotrophic Lateral Sclerosis

    In cranial nerves, common symptoms are atrophy of facial muscles and progressive bulbar palsy (PBP).[flexikon.doccheck.com] Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] ) Males symptomatic; slowly progressive bulbar and limb weakness Family history; fasciculations of facial muscles; gynaecomastia; proximal symmetrical weakness in addition[doi.org]

  • Inclusion Body Myositis

    […] disease of middle-aged , beginning in legs, causing atrophy and weakness of quadriceps, sparing facial and oropharyngeal muscles EMG Abnormal electrical 'irritation', slowing[medical-dictionary.thefreedictionary.com] phosphokinase (CPK) and inflammatory cell infiltration.[emedicine.medscape.com] […] myositis that is not autoimmune and does not respond to immunosuppressive therapy, a clinical diagnosis of exclusion, confirmed by typical histologic features Clinical Slowly progressive[medical-dictionary.thefreedictionary.com]

  • Myoadenylate Deaminase Deficiency

    She had slight muscle weakness in her facial and upper extremities, and severe muscle weakness and atrophy in lower extremities more marked in the proximal portions.[ncbi.nlm.nih.gov] phosphokinase, hypoketotic hypoglycemia, and increased lipid in muscle.[rheumaknowledgy.com] A 46-year-old woman with exertional myalgia developed slowly progressive weakness in her lower extremities.[ncbi.nlm.nih.gov]

  • Kearns-Sayre Syndrome

    PEO6 DNA2 AD PEO w/variable, slowly progressive features; onset: childhood-adulthood Slender build Facial muscle weakness; exertional dyspnea; obstructive sleep apnea; myopathy[ncbi.nlm.nih.gov] […] lactic acid, creatine phosphokinase and protein in CSF, abnormal electroretinography and visual-evoked potential testing.[jmedicalcasereports.biomedcentral.com] […] w/weakness, atrophy, exercise intolerance, myalgia, & cramps; gait disturbance Elevated CK mtDNA single- nucleotide variants 3 Selected example: m.3243A G 4 MT-TL1 Mat Headaches[ncbi.nlm.nih.gov]

  • Muscular Dystrophy-Dystroglycanopathy Type C14

    Specifically, LGMD2B is a slowly progressive disease that causes muscle weakness and wasting ( atrophy ) of the pelvic muscles and muscles of the shoulder girdle. 0003236[rarediseases.info.nih.gov] High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] phosphokinase [ more ] 0003236 Hamstring contractures 0003089 Hyperlordosis Prominent swayback 0003307 Lower limb muscle weakness Lower extremity weakness Lower limb weakness[rarediseases.info.nih.gov]

  • Limb-Girdle Muscular Dystrophy Type 2J

    Specifically, LGMD2B is a slowly progressive disease that causes muscle weakness and wasting ( atrophy ) of the pelvic muscles and muscles of the shoulder girdle. 0003236[rarediseases.info.nih.gov] High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] There is often asymmetric quadriceps, hamstring, biceps, brachioradialis, or calf weakness and atrophy. Muscle pain is common.[emedicine.medscape.com]

  • Sarcotubular Myopathy

    There is often asymmetric quadriceps, hamstring, biceps, brachioradialis, or calf weakness and atrophy. Muscle pain is common.[emedicine.medscape.com] PHOSPHOKINASE INCREASED Abnormality of the musculature ... ...[familydiagnosis.com] Facial weakness, hand weakness, and contractures are uncommon. Progression is slow, and walking is retained. Cardiac and respiratory function is normal.[emedicine.medscape.com]

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