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578 Possible Causes for Creatine Phosphokinase Increased, Facial Muscle Weakness and Progressive Atrophy, Grip Strength Decreased

  • Amyotrophic Lateral Sclerosis

    Prior animal studies have shown that silencing SOD1 led to preservation of grip strength and a delay in the onset of motor function deficits [ 125, 126 ].[doi.org] In cranial nerves, common symptoms are atrophy of facial muscles and progressive bulbar palsy (PBP).[flexikon.doccheck.com] Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org]

  • Limb-Girdle Muscular Dystrophy

    The forearms may become mildly atrophic with decrease in grip strength; the small muscles of the hands are spared.[ncbi.nlm.nih.gov] We present a 19-year-old girl with epilepsy and elevated creatine phosphokinase (CPK) concentration.[ncbi.nlm.nih.gov] Due to increased CPK, myopathy was suspected and muscle biopsy was performed.[ncbi.nlm.nih.gov]

    Missing: Facial Muscle Weakness and Progressive Atrophy
  • Inclusion Body Myositis

    By 14 months, there was a significant decrease in muscle force in mutant VCP mice ( P 0.0001; n 10), as assessed by longitudinal analysis of grip strength as well as acute[doi.org] […] disease of middle-aged , beginning in legs, causing atrophy and weakness of quadriceps, sparing facial and oropharyngeal muscles EMG Abnormal electrical 'irritation', slowing[medical-dictionary.thefreedictionary.com] phosphokinase (CPK) and inflammatory cell infiltration.[emedicine.medscape.com]

  • Muscular Dystrophy

    Abstract Facioscapulohumeral muscular dystrophy is an autosomal-dominant, slowly progressive myopathy that involves facial, shoulder, and upper arm muscles.[ncbi.nlm.nih.gov] The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased creatine phosphokinase (CpK3), electromyography, and genetic testing.[en.wikipedia.org] Facial muscle atrophy and weakness leads to drooping of the lower lip, which has unfavorable functional and aesthetic outcomes.[ncbi.nlm.nih.gov]

    Missing: Grip Strength Decreased
  • Progressive Muscular Atrophy

    Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] Progressive bulbar palsy, also called progressive bulbar atrophy, involves the brain stem—the bulb-shaped region containing lower motor neurons needed for swallowing, speaking[web.archive.org]

    Missing: Grip Strength Decreased
  • Limb-Girdle Muscular Dystrophy Type 2A

    There is often asymmetric quadriceps, hamstring, biceps, brachioradialis, or calf weakness and atrophy. Muscle pain is common.[emedicine.medscape.com] High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] Facial weakness, hand weakness, and contractures are uncommon. Progression is slow, and walking is retained. Cardiac and respiratory function is normal.[emedicine.medscape.com]

    Missing: Grip Strength Decreased
  • Electrical Injury

    Because electrical injury often involves current passing through one or both hands, an evaluation to determine muscle strength, joint motion, endurance, grip strength, and[ecmweb.com] Many electrical trauma patients also experience pain or decreased sensation in their legs.[ecmweb.com]

    Missing: Facial Muscle Weakness and Progressive Atrophy
  • Motor Neuron Disease

    Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] Progressive bulbar palsy, also called progressive bulbar atrophy, involves the brain stem—the bulb-shaped region containing lower motor neurons needed for swallowing, speaking[web.archive.org] Limb weakness with both lower and upper motor neuron signs is almost always evident but less prominent.[web.archive.org]

    Missing: Creatine Phosphokinase Increased
  • Myoadenylate Deaminase Deficiency

    She had slight muscle weakness in her facial and upper extremities, and severe muscle weakness and atrophy in lower extremities more marked in the proximal portions.[ncbi.nlm.nih.gov] phosphokinase, hypoketotic hypoglycemia, and increased lipid in muscle.[rheumaknowledgy.com] A 46-year-old woman with exertional myalgia developed slowly progressive weakness in her lower extremities.[ncbi.nlm.nih.gov]

    Missing: Grip Strength Decreased
  • Glycogen Storage Disease Type 2

    grip strength and decreased ability to jump and hop. 99 Significant weakness attributable to debrancher deficiency most often is recognized in adult life. 21, 53, 58 In the[nature.com] […] deficiency or secondary to altered biomechanics or both, seems to affect trunk and proximal muscles (abdominal muscles, hip extensors, and abductors) and distal muscles, with decreased[nature.com]

    Missing: Facial Muscle Weakness and Progressive Atrophy

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