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80 Possible Causes for Creatine Phosphokinase Increased, Unable to Stand

  • Muscular Dystrophy

    […] or stand without help.[] The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased creatine phosphokinase (CpK3), electromyography, and genetic testing.[] The majority of individuals are unable to sit or stand without support, and some affected children may never learn to walk.[]

  • Duchenne Muscular Dystrophy

    This can result in trouble standing-up. Most are unable to walk by the age of twelve. Affected muscles may look larger due to increased fat content.[] Children with Duchenne may be slower to sit, stand or walk. Most are unable to run and jump properly due to weakness in the core muscles of the body.[] This can result in trouble standing up. Most are unable to walk by the age of 12. Affected muscles may look larger due to increased fat content.[]

  • Limb-Girdle Muscular Dystrophy

    They are usually unable to stand without using their own body to steady themselves and, as such, present with Gower’s sign (where patients use their own hands to push off[] We present a 19-year-old girl with epilepsy and elevated creatine phosphokinase (CPK) concentration.[] Due to increased CPK, myopathy was suspected and muscle biopsy was performed.[]

  • Polymyositis

    There was increased proximal muscle strength and reduction in the creatine phosphokinase level.[] In five patients with refractory juvenile dermatomyositis, muscle strength increased and creatine phosphokinase levels decreased with combination therapy.[]

  • Dermatomyositis

    Elevated creatine phosphokinase increases the suspicion of an inflammatory muscle disease, and muscle biopsy is the definitive diagnostic tool for inflammatory myopathies.[] Creatine phosphokinase (CPK) was increased at 1,319U/L (normal Human Immunodeficiency Virus 1 and 2 antibodies, Epstein-Barr virus and cytomegalovirus antigenaemia.[] Patients often have many lab abnormalities that are seen in classic dermatomyositis though creatine phosphokinase and myoglobin levels are more likely to be normal given the[]

  • Childhood Dermatomyositis

    Abstract Childhood dermatomyositis is an inflammatory condition affecting the skin and muscles that is often associated with a small vessel vasculopathy. According to previous retrospective studies, it is suggested that the severity of the vasculopathy is related to the course of the disease. Sequential in vivo[…][]

  • Tropical Myositis

    She was unable to stand from sitting without using her arms and had bilateral foot drop, but toe extension was preserved ( Box 1 ).[] Muscle enzymes (aldolase, creatine phosphokinase, aminotransferase, and lactic dehygrogenase) are usually normal or slightly raised.[] Interestingly, creatine phosphokinase and aldolase levels is found to be normal in pyomyositis [ 1, 11 ].[]

  • Progressive Muscular Atrophy

    Unable to stand 2 years SMA 3 Kugelberg-Welander disease 18 months-3 years Able to stand and walk Adult SMA 4 Adult Able to stand and walk Adult SMA muscle SMA.[] Children may be able to sit but are unable to stand or walk unaided, and may have respiratory difficulties. The progression of disease is variable.[] SMA type Age at onset Motor Function Age at death SMA 0 Prenatal Unable to breathe, arthrogryposis SMA 1 Werdnig-Hoffmann disease 0-6 months Unable to sit SMA 2 6-18 months[]

  • Rhabdomyolysis

    She was unable to straighten her elbows and knees and had difficulty standing because of soreness in her back muscles.[] […] with common exertional activities (e.g. 20x normal at 1 day after marathon) See Creatine Phosphokinase Myoglobin level increased Increased in urine or serum, but has lower[] […] positive dipstick blood and negative microscopy Intravascular Hemolysis with circulating free Hemoglobin Causes include Transfusion Reaction , DIC, Hemolytic Uremic Syndrome Creatine[]

  • Becker Muscular Dystrophy

    A child with Duchenne MD may: have difficulty walking, running or jumping have difficulty standing up learn to speak later than usual be unable to climb the stairs without[] High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[] Background The dystrophinopathies include a spectrum of muscle diseases The mild end of the spectrum includes asymptomatic increases in serum concentration of creatine phosphokinase[]

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