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272 Possible Causes for Cryoglobulinemia, Epistaxis

  • Multiple Myeloma

    Patients with a high tumor volume may present with epistaxis.[symptoma.com] Type I multiple myeloma-associated cryoglobulinemia was diagnosed.[ncbi.nlm.nih.gov] Dizziness, confusion, blurred vision, headaches, epistaxis, cerebrovascular event - due to hyperviscosity.[patient.info]

  • Cryoimmunoglobulinemic Syndrome

    ., headache, confusion, blurry or loss of vision, hearing loss, and epistaxis ; b) deposit in small arteries and capillaries thereby plugging these blood vessels and causing[en.wikipedia.org] Figure 2 Cutaneous manifestations of mixed cryoglobulinemia (MC).[ojrd.biomedcentral.com] M. : Cryoglobulinemia and disease — Ann. intern. Med. 73 , 95, 1970. PubMed Google Scholar 2. Barr D. P., Reader G. G., Wheeler C. H. : Cryoglobulinemia.[link.springer.com]

  • Sjögren Syndrome

    Serum cryoglobulinemia was measured in all patients.[ncbi.nlm.nih.gov] Autoimmune diseases are sometimes associated with immune-mediated renal diseases and cryoglobulinemia is one of the causes.[ncbi.nlm.nih.gov] […] serological parameters that have been associated with lymphoma development in patients with Sjögren's syndrome, the presence of palpable purpura, low C4 and mixed monoclonal cryoglobulinemia[ncbi.nlm.nih.gov]

  • Waldenstrom Macroglobulinemia

    A 71-year-old woman presented with malaise, skin bruising, epistaxis, and gingival bleeding of recent and prompt onset. There was no adenopathy.[ncbi.nlm.nih.gov] Type II (mixed) cryoglobulinemia is a systemic vasculitis that may affect many organs, including the skin, leading to ulcerations secondary to immune complex deposition.[ncbi.nlm.nih.gov] Clinically, patients may present with fatigue, weight loss, peripheral neuropathy or symptoms of hyperviscosity, including headache, blurred vision or epistaxis.[ncbi.nlm.nih.gov]

  • Hyperviscosity Syndrome

    […] erosive rheumatoid arthritis with profoundly elevated rheumatoid factor (57,400 IU/ml; normal 35) who presented with findings consistent with HVS: profound weakness, headache, epistaxis[ncbi.nlm.nih.gov] Hyperviscosity syndrome is much more common in monoclonal than in mixed or polyclonal cryoglobulinemia.[ncbi.nlm.nih.gov] Patients may present with any of the following: Spontaneous gum bleeding Epistaxis Rectal bleeding Menorrhagia Persistent bleeding after minor procedures Visual changes range[emedicine.medscape.com]

  • Thrombocytopenia

    It presents in infancy or in neonates (in severe cases) with patients bruising easily along with further manifestations of thrombocytopenia including epistaxis, petechiae,[enerca.org] […] stippling Thalassemia, chronic alcohol use, lead or metal poisoning Ribosomal precipitate (appears as blue granules) throughout the cytoplasm of the red blood cell Cryoglobulin Cryoglobulinemia[aafp.org]

  • Perforated Nasal Septum

    Complications from nasal surgery Chronic epistaxis Aggressive digital nasal cleaning (nose picking) Nasal piercings Chemical inhalants Cocaine use Small anterior lesions may[inhealth.com] These cases occur less frequently as a result of infection with Syphilis, HIV, fungus or varicella. 5) Neoplastic : Other rare causes include carcinoma, T-cell lymphoma and cryoglobulinemias[drbrennerarticles.com] […] can cause secondary vasculitis are: systemic lupus erythematosus, rheumatoid arthritis, polymyalgia rheumatica, scleroderma, Wegener s granulomatosis, temporal arteritis, cryoglobulinemia[tmj.ro]

  • Vasculitis

    Upper respiratory tract lesions include recurrent rhinitis, sinusitis, epistaxis and serous otitis media.[symptoma.com] It represents 70–80% of cryoglobulinemia renal diseases and it is strongly associated with the type II IgM κ mixed cryoglobulinemia.[journals.lww.com] Presenting features may include purpuric rash, recurrent sinusitis, epistaxis, shortness of breath, and/or hemoptysis from alveolar hemorrhage.[emedicine.medscape.com]

  • Microscopic Polyangiitis

    […] with polyangiitis (GPA) by absence of granulomatous inflammation Clinical Presentation Constitutional – weight loss, fever, myalgias Otorhinolaryngological – oral ulcers, epistaxis[arupconsult.com] Patient had a flare-up consisting of bilateral episcleritis and epistaxis after discontinuing prednisone.[omicsonline.org] Diseases such as SLE, Henoch-Schönlein purpura, cryoglobulinemia can produce small-vessel vasculitis with immune complexes.[forums.studentdoctor.net]

  • Granulomatosis with Polyangiitis

    CASE REPORT A 67-year-old woman was referred for evaluation of episodes of epistaxis and recurrent severe sinusitis.[ncbi.nlm.nih.gov] .- ) ankylosing spondylitis ( M45 ) congenital syphilis ( A50.5 ) cryoglobulinemia ( D89.1 ) early congenital syphilis ( A50.0 ) plasminogen deficiency ( E88.02 ) schistosomiasis[icd10data.com] Upper respiratory tract: Sinus pain, serosanguineous or purulent discharge, and epistaxis may occur.[merckmanuals.com]

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