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64 Possible Causes for Cryoglobulinemia, Fatigue, Yellow Discoloration of the Skin

  • Chronic Hepatitis C

    Approximately 80% of patients with hepatitis C virus infection develop chronic liver disease as cirrhosis, and 40% develop autoimmune complications as mixed cryoglobulinemia[ncbi.nlm.nih.gov] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org] Symptoms can include: fatigue muscle aches loss of appetite Most symptoms of chronic hepatitis C don’t appear until cirrhosis develops and the liver begins to fail.[healthline.com]

  • Viral Hepatitis

    This is followed by the prodromal period, which is characterized by acute manifestations such as fatigue, malaise, fever, anorexia, nausea, emesis, abdominal pain, urticaria[symptoma.com] HCV RNA can be demonstrated in the tumor as well as in surrounding liver tissue although HCV RNA cannot be integrated in the hepatocytic DNA. 3--Essential cryoglobulinemia[meddean.luc.edu] The most notable symptom of acute viral hepatitis is jaundice, which is a yellow discoloration of the skin and the whites of the eyes.[patients.gi.org]

  • Hepatitis B

    RESULTS: Clinical history, examinations, and laboratory results suggest HBV-associated cryoglobulinemia and vasculitis.[ncbi.nlm.nih.gov] Jaundice (a yellow discoloration of eyes and skin), which is usually a sign of liver damage, may not occur.[web.archive.org] Fatigue Other names Exhaustion, weariness, tiredness, languidness, languor, lassitude, listlessness Specialty Internal medicine, Family practice, Psychiatry, Psychology Fatigue[en.wikipedia.org]

  • Syphilis

    Other, less common signs and symptoms may include fever, swollen lymph glands, sore throat, patchy hair loss, headaches, weight loss, muscle aches, and fatigue.[beforeplay.org] The rash usually does not cause itching but may be associated with fever, swollen lymph nodes, sore throat, headache, muscle aches, and fatigue.[jamanetwork.com] […] but is usually present on the palms of the hands and soles of the feet Sores in the mouth and on the genitals or anus Swollen lymph glands Mild fever Sore throat Headache Fatigue[healthychildren.org]

  • Hepatitis C

    Furthermore, DCV-TRIO was well tolerated in all studies with reported adverse events (AEs) with an incidence of at least 10% mostly being headache, diarrhea, fatigue and nausea[ncbi.nlm.nih.gov] Monoclonal IgM rheumatoid factor secreted by CD5-negative B cells during mixed cryoglobulinemia.[doi.org] Signs and symptoms include: Bleeding easily Bruising easily Fatigue Poor appetite Yellow discoloration of the skin and eyes (jaundice) Dark-colored urine Itchy skin Fluid[mayoclinic.org]

  • Cold Agglutinin Disease

    Cold agglutinin disease manifests as acute or chronic hemolytic anemia, with associated pallor and fatigue.[web.archive.org] Rituximab therapy has been found to be effective in mixed cryoglobulinemia, with decreases in cryoglobulin values and improvement in complement values.[ncbi.nlm.nih.gov] Some people experience fatigue and jaundice yellowing of the skin and/or the whites of the eyes.[sunridgemedical.com]

  • Autoimmune Disease

    Although each disease is unique, many share hallmark symptoms, such as fatigue, dizziness, and low-grade fever.[womenshealth.gov] Autoimmune diseases are the most frequently associated disorders and include rheumatoid arthritis, systemic lupus erythematosus, cryoglobulinemia, pemphigus vulgaris, and[ncbi.nlm.nih.gov] In severe cases the individual can develop a yellow discoloration to the skin and eyes known as jaundice.[primaryimmune.org]

  • Infectious Mononucleosis

    Arima, Mami Tamai, Satoshi Yamasaki, Hideki Nakamura, Hiroyuki Moriuchi and Atsushi Kawakami, An elderly patient with chronic active Epstein–Barr virus infection with mixed cryoglobulinemia[dx.doi.org] skin.[hopkinsmedicine.org] A diagnosis of chronic fatigue syndrome (CFS) was made according to the international diagnostic criteria [ 13 ] in post-infective fatigue cases included in this study.[dx.doi.org]

  • Cytomegalovirus Mononucleosis

    This is the first report of transient pseudothrombocytopenia in CMV mononucleosis with mixed cryoglobulinemia.[ncbi.nlm.nih.gov] skin.[hopkinsmedicine.org] Presentation in this disease roughly consists of a triad of fatigue, fever, and lymphadenopathy.[symptoma.com]

  • Liver Cirrhosis

    In the presented case, the authors describe an obese middle-aged man that presented to the emergency department for persistent oedema, scleral icterus and fatigue.[ncbi.nlm.nih.gov] […] non-organ-specific autoantibody production up to overt non-Hodgkin's lymphoma along a continuous step-by-step model of B-cell lymphomagenesis, where the intermediated mixed cryoglobulinemia[ncbi.nlm.nih.gov] Yellow discoloration in the skin and eyes (jaundice) Fluid accumulation in your abdomen (ascites) Spiderlike blood vessels on your skin Redness in the palms of the hands[mayoclinic.org]

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