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30 Possible Causes for Cryoglobulinemia, Liver Tenderness, Yellow Discoloration of the Skin

  • Viral Hepatitis

    HCV RNA can be demonstrated in the tumor as well as in surrounding liver tissue although HCV RNA cannot be integrated in the hepatocytic DNA. 3--Essential cryoglobulinemia[meddean.luc.edu] Physical exam Assessment of the patient may yield remarkable findings such as jaundice, scleral icterus, and an enlarged and tender liver.[symptoma.com] The most notable symptom of acute viral hepatitis is jaundice, which is a yellow discoloration of the skin and the whites of the eyes.[patients.gi.org]

  • Chronic Hepatitis C

    Approximately 80% of patients with hepatitis C virus infection develop chronic liver disease as cirrhosis, and 40% develop autoimmune complications as mixed cryoglobulinemia[ncbi.nlm.nih.gov] People with chronic liver disease may be at risk for a type of blood clot in the stomach area.[us.promacta.com] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org]

  • Hepatitis B

    RESULTS: Clinical history, examinations, and laboratory results suggest HBV-associated cryoglobulinemia and vasculitis.[ncbi.nlm.nih.gov] The tenderness in the liver region may lead to consideration of hepatic Amoebiasis or Typhoid.[tmb.ie] Jaundice (a yellow discoloration of eyes and skin), which is usually a sign of liver damage, may not occur.[web.archive.org]

  • Hepatitis C

    Monoclonal IgM rheumatoid factor secreted by CD5-negative B cells during mixed cryoglobulinemia.[doi.org] Symptoms of acute hepatitis C may include: Achiness in the joints or muscles Mild fatigue (feeling tired) Nausea (feeling sick to the stomach) Loss of appetite Tenderness[my.clevelandclinic.org] Signs and symptoms include: Bleeding easily Bruising easily Fatigue Poor appetite Yellow discoloration of the skin and eyes (jaundice) Dark-colored urine Itchy skin Fluid[mayoclinic.org]

  • Liver Cirrhosis

    […] non-organ-specific autoantibody production up to overt non-Hodgkin's lymphoma along a continuous step-by-step model of B-cell lymphomagenesis, where the intermediated mixed cryoglobulinemia[ncbi.nlm.nih.gov] He'll also examine you to check if your liver is tender or larger than it should be. Tests. If your doctor suspects cirrhosis, he will do a blood test.[webmd.com] Yellow discoloration in the skin and eyes (jaundice) Fluid accumulation in your abdomen (ascites) Spiderlike blood vessels on your skin Redness in the palms of the hands[mayoclinic.org]

  • Infectious Mononucleosis

    Arima, Mami Tamai, Satoshi Yamasaki, Hideki Nakamura, Hiroyuki Moriuchi and Atsushi Kawakami, An elderly patient with chronic active Epstein–Barr virus infection with mixed cryoglobulinemia[dx.doi.org] Apply a heating pad or a warm washcloth to swollen neck glands to help relieve tenderness.[uhs.umich.edu] skin.[hopkinsmedicine.org]

  • Liver Disease

    Keratoconjunctivitis (sicca syndrome), glomerulonephritis, skin disorders (for example, lichen planus, porphyria cutanea tarda), neuropathy, and immune dysfunction (for example, cryoglobulinemia[ssa.gov] In the early stage of any liver disease, your liver may become inflamed. It may become tender and enlarged.[liverfoundation.org] Symptoms of liver diseases include weakness and fatigue, weight loss, nausea, vomiting, and yellow discoloration of the skin (jaundice).[medicinenet.com]

  • Hepatitis A

    Transverse myelitis Renal findings Acute tubular necrosis Interstitial nephritis Mesangial proliferative glomerulonephritis Nephrotic syndrome Other findings Cutaneous vasculitis Cryoglobulinemia[web.archive.org] Hepatitis A is a viral infection of the liver. The liver becomes inflamed, tender, and swollen. How does it occur? Hepatitis A is caused by the hepatitis A virus.[web.archive.org] The most common symptoms are as follows: Nausea Vomiting Diarrhea, especially in children Low-grade fever Loss of appetite Rash Tiredness, fatigue Jaundice - A yellow discoloration[web.archive.org]

  • Non-viral Hepatic Infection

    The most common extrahepatic condition is mixed cryoglobulinemia. Cryoglobulins are found in 50% of patients with chronic HCV infection.[medsci.org] The liver is enlarged and tender. Liver damage causes increased blood levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and bilirubin.[atsu.edu] Hepatitis may occur with limited or no symptoms, but often leads to yellow discoloration of the skin, mucus membranes, and conjunctivae, poor appetite and malaise.[disabled-world.com]

  • Syphilis

    Secondary Syphilis In this stage, the pathogen spreads through the blood to the skin, liver, joints, lymph nodes, muscles, and brain.[healthcommunities.com] Swelling and hardening of lymph nodes in the inner thighs and groin is also common and may cause tenderness. Lesions usually heal without treatment within 6 weeks.[healthcommunities.com]

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