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51 Possible Causes for Cryoglobulinemia, Pruritus, Yellow Discoloration of the Skin

  • Chronic Hepatitis C

    Approximately 80% of patients with hepatitis C virus infection develop chronic liver disease as cirrhosis, and 40% develop autoimmune complications as mixed cryoglobulinemia[ncbi.nlm.nih.gov] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org] Minor side effects noted were nausea seen in five (7.7%) patients, insomnia and headache in four (6.2%) patients each, and pruritus in one (1.5%) patient.[ncbi.nlm.nih.gov]

  • Hepatitis B

    RESULTS: Clinical history, examinations, and laboratory results suggest HBV-associated cryoglobulinemia and vasculitis.[ncbi.nlm.nih.gov] Jaundice (a yellow discoloration of eyes and skin), which is usually a sign of liver damage, may not occur.[web.archive.org] A 52-year-old man complained of worsening appetite, abdominal distension, and pruritus.[ncbi.nlm.nih.gov]

  • Hepatitis C

    Monoclonal IgM rheumatoid factor secreted by CD5-negative B cells during mixed cryoglobulinemia.[doi.org] Signs and symptoms include: Bleeding easily Bruising easily Fatigue Poor appetite Yellow discoloration of the skin and eyes (jaundice) Dark-colored urine Itchy skin Fluid[mayoclinic.org] These neuropeptides may mediate the cutaneous neurogenic inflammation and pruritus in prurigo nodularis.[doi.org]

  • Liver Cirrhosis

    […] non-organ-specific autoantibody production up to overt non-Hodgkin's lymphoma along a continuous step-by-step model of B-cell lymphomagenesis, where the intermediated mixed cryoglobulinemia[ncbi.nlm.nih.gov] Yellow discoloration in the skin and eyes (jaundice) Fluid accumulation in your abdomen (ascites) Spiderlike blood vessels on your skin Redness in the palms of the hands[mayoclinic.org] Severe pruritus may require treatment with ultraviolet light or plasmapheresis.[patient.info]

  • Hepatitis

    […] mellitus, which occurs three times more frequently in HCV-infected persons; glomerulonephritis, a type of kidney disease caused by inflammation of the kidney; essential mixed cryoglobulinemia[patients.gi.org] A hepatitis infection is also associated with jaundice, a yellow discoloration of the skin and a yellowish color to the whites of the eyes.[healthychildren.org] When they persist, they cause prolonged jaundice, elevated alkaline phosphatase, and pruritus, despite general regression of inflammation.[merckmanuals.com]

  • Viral Hepatitis

    HCV RNA can be demonstrated in the tumor as well as in surrounding liver tissue although HCV RNA cannot be integrated in the hepatocytic DNA. 3--Essential cryoglobulinemia[meddean.luc.edu] The most notable symptom of acute viral hepatitis is jaundice, which is a yellow discoloration of the skin and the whites of the eyes.[patients.gi.org] During the past decade, NTX has been shown to be safe and effective in the treatment of pruritus associated with severe jaundice caused by severe and sometimes life-threatening[ncbi.nlm.nih.gov]

  • Erythema Elevatum Diutinum

    […] the buttocks may also be involved. [2] Antecedent bacterial infections, collagen vascular diseases, myeloproliferative diseases, human immunodeficiency virus infection, cryoglobulinemia[idoj.in] Erythema elevatum diutinum (EED) is a rare type of skin disorder characterized as raised papules or plaques with a skin discoloration of red, purple, brown or yellow.[patientslikeme.com] 678 206 Pruritus ani 686 207 Pruritus vulvae 688 208 Pseudofolliculitis barbae 691 209 Pseudoxanthoma elasticum 695 210 Psoriasis 697 211 Psychogenic excoriation 708 212[books.google.de]

  • Autoimmune Hepatitis

    cryoglobulinemia is more common.[merckmanuals.com] discoloration of the skin and the whites of the eyes ( jaundice ).[labtestsonline.org] Fatigue Abdominal pain Joint pain Itching (pruritus) Jaundice An enlarged liver Abnormal blood vessels on the skin (spider angiomas) Nausea and vomiting Loss of appetite Skin[columbiasurgery.org]

  • Psoriasis

    In adults, Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, systemic lupus erythematosus, and mixed cryoglobulinemia (see these terms) should also[orpha.net] discoloration of the nails known as the oil drop or salmon spot, dryness, thickening of the skin under the nail (subungual hyperkeratosis), loosening and separation of the[en.wikipedia.org] The mediators involved in psoriatic pruritus have not been fully established.[ncbi.nlm.nih.gov]

  • Syphilis

    Papules vary from 0.5 to 2 cm in diameter, often cause pruritus, and can be confused with the lesions of psoriasis, pityriasis rosea, and drug eruptions. 107 These skin lesions[glowm.com]

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