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63 Possible Causes for Cryoglobulinemia, Scleritis and Episcleritis

  • Sjögren Syndrome

    Serum cryoglobulinemia was measured in all patients.[ncbi.nlm.nih.gov] Autoimmune diseases are sometimes associated with immune-mediated renal diseases and cryoglobulinemia is one of the causes.[ncbi.nlm.nih.gov] […] serological parameters that have been associated with lymphoma development in patients with Sjögren's syndrome, the presence of palpable purpura, low C4 and mixed monoclonal cryoglobulinemia[ncbi.nlm.nih.gov]

  • Polyarteritis Nodosa

    Like episcleritis it has a tendency to recur.[medical-dictionary.thefreedictionary.com] 5 negative predictive parameters (indirect immunofluorescence detection of antineutrophil cytoplasmic antibody; asthma; ear, nose, and throat signs; glomerulopathy; and cryoglobulinemia[ncbi.nlm.nih.gov] […] microscopic polyangiitis Infection Mycobacterium tuberculosis Endocarditis Hepatitis B/ hepatitis C Treponema pallidum Cytomegalovirus Epstein-Barr virus HIV Plasmodium spp Cryoglobulinemia[arupconsult.com]

  • Rheumatoid Arteritis

    Examples of vasculitis include: Kawasaki disease, Behçet's disease, Polyarteritis nodosa, Granulomatosis with polyangiitis,, Cryoglobulinemia, Takayasu's arteritis, Churg-Strauss[medicinenet.com] […] arthritis polymyalgia rheumatica scleroderma granulomatosis with polyangiitis (Wegener's granulomatosis) micropolyangiitis (occurs primarily in kidneys) temporal arteritis cryoglobulinemia[resources.lupus.org]

  • Syphilis

    Syphilis is a sexually transmitted disease that can affect multiple organ systems, with central nervous system involvement at any stage. We present a 53-year-old woman with an unusual truncal rash with painful anogenital lesions, accompanied by patchy alopecia, oral lesions, photophobia and hoarseness. She was found[…][ncbi.nlm.nih.gov]

  • Autoimmune Disease

    Patients with scleritis have tenderness on palpation, while those with episcleritis do not.[aafp.org] Autoimmune diseases are the most frequently associated disorders and include rheumatoid arthritis, systemic lupus erythematosus, cryoglobulinemia, pemphigus vulgaris, and[ncbi.nlm.nih.gov] Celiac Disease Multifocal Motor Neuropathy (MNN) Peripheral Neuropathy Associated with Protein Abnormalities Anti-MAG (associated with Monoclonal Gammopathy) Amyloidosis Cryoglobulinemia[foundationforpn.org]

  • Vasculitis

    The most frequent manifestations at diagnosis were urticaria (100%), arthritis (88%), followed by biopsy-proven glomerulonephritis (19%), episcleritis/scleritis (19%) and[ncbi.nlm.nih.gov] It represents 70–80% of cryoglobulinemia renal diseases and it is strongly associated with the type II IgM κ mixed cryoglobulinemia.[journals.lww.com] The more prominent ocular manifestations include scleritis/episcleritis or orbital disease.[mdedge.com]

  • Hypocomplementemic Vasculitis

    scleritis 3 (19%) Recurrent abdominal pain 2 (13%) Anti-C1q antibody 16 (100%) Histopathology diagnosis 13 (81%) ESRD 2 (13%) Death 2 (13%) Serology data at diagnosis ANA[acrabstracts.org] Hypertrophic osteoarthropathy, cutaneous vasculitis, and mixed-type cryoglobulinemia in a patient with nasopharyngeal carcinoma.[scielo.br] Keywords: Complement C1q, Complement C3, Complement C4, Cryoglobulinemia, Hepatitis C, chronic, Systemic vasculitis, Urticaria, Vasculitis Abstract A vasculite urticariforme[ncbi.nlm.nih.gov]

  • Scleromalacia Perforans

    Scleritis and episcleritis. Br J Ophthalmol 1976 ; 60 : 163 –91. 3 Sainz de la Maza M, Jabbur NS, Foster CS. Severity of scleritis and episcleritis.[academic.oup.com] X-rays (for spondyloarthropathy), sinus imaging (for Granulomatosis with polyangiitis), and viral hepatitis panel (hepatitis B for polyarteritis nodosa and hepatitis C for cryoglobulinemia[touchophthalmology.com] […] systemic lupus erythematosus, relapsing polychondritis, polyarteritis nodosa, inflammatory bowel disease, sarcoidosis, juvenile rheumatoid arthritis, ankylosing spondylitis, cryoglobulinemia[bmcresnotes.biomedcentral.com]

  • Cogan Syndrome

    Anemia is present, initially, in one-third of patients, and about 20% have cryoglobulinemia (cold precipitating proteins in the blood) or eosinophilia (increased number of[vasculitisfoundation.org] "Atypical" Cogans syndrome is the association of the typical hearing symptoms with other ocular symptoms including scleritis or episcleritis, retinitis, optic neuritis, glaucoma[dizziness-and-balance.com] Interstitial keratitis is the characteristic ocular feature, although this is not mandatory for the diagnosis; moreover, ocular manifestations such as scleritis, episcleritis[jrheum.org]

  • Secondary Syphilis

    Regarding the ocular surface, syphilis can cause conjunctivitis, 6 episcleritis or scleritis. 7,8 Interstitial keratitis (See Figure 1), often associated with conjunctival[reviewofophthalmology.com] Regarding the ocular surface, syphilis can cause conjunctivitis, 6 episcleritis or scleritis. 7,8 Interstitial keratitis (See Figure 1) , often associated with conjunctival[reviewofophthalmology.com]

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