Possible Causes for cryptococcus antigen Cryptococcal Meningitis Five days later, the CSF was positive for Cryptococcus antigen. We administered amphotericin B and flucytosine, followed by fluconazole. [ncbi.nlm.nih.gov] Cryptococcal meningitis was confirmed by lumbar puncture with positive cryptococcus antigen in the cerebrospinal fluid. [ncbi.nlm.nih.gov] The diagnosis of cryptococcal meningitis was obtained later on by simultaneous plasma and CSF Cryptococcus antigen detection. [ncbi.nlm.nih.gov] Cryptococcosis In addition to testing for cryptococcal antigen, patients with presumed disease due to Cryptococcus neoformans should have clinical specimens (eg, bronchoalveolar lavage fluid [mayomedicallaboratories.com] Cryptococcal capsular polysaccharide antigen test of the CSF or serum was conducted using the latex-Cryptococcus antigen detection system (Immuno-Mycologics, Inc., USA). [bmcinfectdis.biomedcentral.com] - Detection of Cryptococcus neoformans antigen in body fluids by latex particle agglutination. Proc. Soc. exp. biol. Med., 114: 64-67, 1963. [ Links ] 5. [scielo.br] Pulmonary Cryptococcosis Furthermore, the serum cryptococcus antigen was negative. Therefore, thoracoscopic partial lung resection was performed. [ncbi.nlm.nih.gov] The titer of Cryptococcus antigen latex agglutination test was 1:1,280. [ncbi.nlm.nih.gov] Cytology of the bronchial lavage showed a small number of Periodic acid-Schiff-positive bodies, suggesting Cryptococcus species. [ncbi.nlm.nih.gov] Disseminated Cryptococcosis Laboratory data revealed CD4 lymphocytopenia and a tissue culture of the skin nodule was positive for Cryptococcus neoformans. [ncbi.nlm.nih.gov] antigen titer of 1:32). [ncbi.nlm.nih.gov] Titers of Cryptococcus neoformans capsular antigen in CSF or 1/1000 were found in 36.1 and or 1/1000 in 73.6 of serum samples. [bases.bireme.br] AIDS-Associated Meningoencephalitis […] testing if resources allow. [ 6 ] Cryptococcus antigen testing is an alternative to the India ink for the diagnosis of cryptococcal meningitis. [ 7 ] Cryptococcus antigen [pubs.sciepub.com] The blood or spinal fluid can be tested for cryptococcus in two ways. A “CRAG” test looks for an antigen (a protein) produced by cryptococcus. [aidsinfonet.org] Both in serum and CSF, the antigen titre was done. Antigen titre in serum was 132 and in CSF it was more than 32. [ijmm.org] Subcutaneous Abscess After surgical incision and drainage was performed, Cryptococcus neoformans var. neoformans was the only pathogen cultured from the lesion. [thieme-connect.com] An agglutination test for the capsular antigen in serum displayed negative results and the immunological work-up revealed no underlying immunodeficiency. [thieme-connect.com] Nach chirurgischer Inzision und Drainage konnte Cryptococcus neoformans var. neoformans als einziger Krankheitserreger aus dem Drainagesekret kultiviert werden. [thieme-connect.com] Factitious Fever antigen, histoplasmosis, coccidioidomycosis) • Protozoal and parasitic (toxoplasmosis, amoebiasis, schistosomiasis, leishmaniasis, trypanosomiasis) • PCR e.g for tuberculosis [studyslide.com] Bacterial (chlamydial infection, Q fever, brucellosis, mycoplasma infection, syphilis, leptospirosis, Lyme disease, Yersinia infection, streptococcal infection) • Fungal(Cryptococcus [studyslide.com] Primary Central Nervous System Vasculitis Additional CSF tests with negative results included the venereal disease research laboratory test, Cryptococcus antigen test, fungal and bacterial cultures, and polymerase [the-rheumatologist.org] antigen, HSV 1,2 HIV 1,2 Epstein–Barr virus (EBV), West Nile, venereal disease research laboratory, varizella zoster, and Borrelia burgdorferi. [surgicalneurologyint.com] […] lobe on sagittal section A lumbar puncture was performed, which was negative for an infectious etiology including routine, acid-fast bacilli (AFB), and fungal cultures, cryptococcus [surgicalneurologyint.com] Obstructive Hydrocephalus The diagnosis of cryptococcal meningitis was obtained later on by simultaneous plasma and CSF Cryptococcus antigen detection. [ncbi.nlm.nih.gov] Cryptococcus neoformans (formerly C. neoformans var. grubii [serotype A]) was then identified by PCR. Clinical improvement was obtained with antifungal therapy. [ncbi.nlm.nih.gov] Meningitis […] neoformans antigens; serology for Lyme disease,brucellosis, syphilis. ( ) Albumin Quotient measures the bloodCSF barrier permeability. (#) Calculated vs 5 patients with OHP [docslide.us] Performing a cryptococcal antigen assay on CSF can be helpful in these situations. [emedicine.medscape.com] […] virus, Cytomegalovirus, Epstein-Barr virus, Enterovirus,Mycobacterium tuberculosis; Gram, acid-fast stain and microbiological cultures; search for Aspergillus fumigatus and Cryptococcus [docslide.us] Astrocytoma Astrocytes might participate in cryptococcosis either as a host or by responding to fungal antigens. [ncbi.nlm.nih.gov] To determine the infectivity of Cryptococcus neoformans var. grubii and Cryptococcus gattii in a human astrocytoma cell line and the induction of major histocompatibility [ncbi.nlm.nih.gov] Meningoencephalitis […] of Cryptococcus. [ncbi.nlm.nih.gov] The CSF cryptococcal antigen test was not repeated. The blood that had been collected upon admission was microbiologically negative. [bmcresnotes.biomedcentral.com] Diagnosis of central nervous system cryptococcosis relies on a spectrum of methods but has improved with lateral flow diagnostic assays that detect capsular polysaccharide antigens [ncbi.nlm.nih.gov] Lymphadenitis Serological detection of cryptococcus antigens by latex agglutination and culture are also used. [atmph.org] Pittsburgh Pneumonia […] testing (Legionella pneumophila, Histoplasma capsulatum, Streptococcus pneumoniae), PCR studies (CMV, HHV6), serum antigen testing (cryptococcus, galactomannan), and other [emedicine.medscape.com] […] established to be useful for initiating and guiding antibiotic therapy. [49, 50, 51] Other routine laboratory studies may be clinically indicated, such as viral nasal swabs, urine antigen [emedicine.medscape.com] Erythema Nodosum Cryptococcus neoformans antigen and Sporothrix schenckii antibody tests were performed using the latex agglutination method. [cdc.gov] […] neoformans 0 --- Sporothrix schenckii 0 --- Positive fungal serum antigen (acute serum) (n 9) C. neoformans 0 --- Positive immunoglobulin M Mycoplasma pneumoniae antibody [cdc.gov] […] capsulatum mycelial 0 --- H. capsulatum yeast 0 --- Paracoccidioides brasiliensis 0 --- Blastomycosis dermatitidis 0 --- Positive fungal serum antibody (paired sera) (n 9) Cryptococcus [cdc.gov] Histoplasma Meningitis There appears to be no cross-reactivity between Cryptococcus neoformans and Histoplasma antigen testing, and cryptococcosis appears to be at most, a rare cause of positive [experts.umn.edu] Mobility of human neutrophils in response to Cryptococcus neoformans cells, culture filtrate antigen, and individual components of the antigen. [wwwnc.cdc.gov] Seven of 11 (63.6%) other CNS fungal meningitis cases (five Cryptococcus, two Aspergillus, two Blastomyces, one Candida, and one suspected fungal meningitis) had CSF BDG 80 [aspergillus.org.uk] Chronic Hepatitis C Five days later, the CSF was positive for Cryptococcus antigen. We administered amphotericin B and flucytosine, followed by fluconazole. [ncbi.nlm.nih.gov] The cerebral spinal fluid (CSF) revealed a white blood cell count of 205/mm(3), 51 mg/dL protein, 35 mg/dL glucose, and negative Cryptococcus antigen. [ncbi.nlm.nih.gov] Susac Syndrome […] spp [ 7 ], mycobacteria [ 8 ], JC virus [ 9 ], or also to auto-antigens [ 10, 11 ]. [aidsrestherapy.biomedcentral.com] […] spp[7], mycobacteria [8], JC virus [9], or also to auto-antigens [10,11]. [ncbi.nlm.nih.gov] […] leading to CD4 cells increase and, more importantly, plasma HIV-RNA reduction. [ 6 ] IRIS reflects a paradoxycal inflammatory response to opportunistic pathogens, such as Cryptococcus [aidsrestherapy.biomedcentral.com] Autoimmune Hepatitis Urine histoplasma and Cryptococcus antigens were negative. Anti-nuclear, anti-smooth muscle, anti-LKM and anti-mitochondrial antibodies were negative. [bloodjournal.org] Viral Meningitis Coccidioides antibody CCOCCI 4 3 Cryptococcus antigen CRAGC 1 0.5 cytology CCSF 1 Cannot be split for other tests. Left over from other CSF samples cannot be used. [wiki.umms.med.umich.edu] Other studies can include acid-fast stain and tuberculosis PCR/Culture, VDRL, and antigen testing for cryptococcus. [emlyceum.com] If suspecting cryptococcal meningitis, a specimen should also be submitted for cryptococcus antigen screen. Do not refridgerate as this can inhibit Histoplasma growth. [wiki.umms.med.umich.edu] Pleomorphic Xanthoastrocytoma We do not perform biopsy for hydatid cysts Imaging Brain, eye, and splenic cysts may not produce detectable amount of antibodies CNS cryptococcosis [52] / / Positive CSF antigen [wikidoc.org] […] coccidioidomycosis) CSF lymphocytic pleocytosis Elevated CSF proteins and lactate Low CSF glucose Dilated perivascular spaces Basal ganglia pseudocysts Soap bubble brain lesions (cryptococcus [wikidoc.org] HIV Infection The diagnosis is based on detection of cryptococcal antigen or culture of Cryptococcus neoformans in the cerebrospinal fluid (CSF). [journalofethics.ama-assn.org] (cryptococcosis), Histoplasma (histoplasmosis), or Mycobacterium tuberculosis CT or MRI CSF stains, antigen tests, PCR, and cultures Treatment of cause Outcomes improved [msdmanuals.com] […] the immunodeficiency (no drugs are effective for JC virus) Usually fatal within a few months May respond to antiretroviral drugs Subacute meningitis Coccidioidomycosis, Cryptococcus [msdmanuals.com] Bone Necrosis Serum Cryptococcus, Coccidioides, and Histoplasma capsulatum antigens were negative. [academic.oup.com] Morphologic differential diagnosis included Cryptococcus species and Candida species, among others. [academic.oup.com] Lyme Meningoencephalitis For example, tests may be done to detect proteins released by Cryptococcus neoformans (called antigen testing). [merckmanuals.com] Systemic Candidiasis ('IDTP') antibody • Sporothrix schenckii antibody • Antigen detection: • Cryptococcus neoformans capsular polysaccharide antigen Yeast Agglutination: • Cryptococcus neoformans [gilbertssyndrome.com] antigen • Blastomyces A antigen • Coccidioides antigen • Aspergillus fumigatus antigen Latex Agglutination tests • Antibody detection: • Histoplasma antibody • Coccidioides [gilbertssyndrome.com] Here is a listing provided by Cerodex Labs, a wholly owned subsidiary of IMMY: Complement Fixation tests for antibody to: • Histoplasma mycelial antigen • Histoplasma yeast [gilbertssyndrome.com] Cervical Lymphadenitis His CD4 T-cell count was 101 cells/μl, serum cryptococcal antigen titer was 1: 256 and VL was undetectable. [academic.oup.com] CSF/serum cryptococcal antigen titer was more than 1 : 2048. This patient was treated with amphotericin B (0.7 mg/kg/day) and fluconazole (600 mg/day). [academic.oup.com] Secondary prophylaxis for Cryptococcus infection with fluconazole at a dose of 200 mg/day was discontinued 10 months later when his CD4 T-cell count returned to 202 cells/ [academic.oup.com] Multiple Sclerosis Order rapid antigen testing, as appropriate. [emedicine.medscape.com] This may include tests for group A streptococci, pneumococci, C difficile, Cryptococcus species, RSV, influenza virus, adenovirus, parainfluenza, human metapneumovirus, and [emedicine.medscape.com] Cerebral Angiitis Additional CSF tests with negative results included the venereal disease research laboratory test, Cryptococcus antigen test, fungal and bacterial cultures, and polymerase [the-rheumatologist.org] antigen, HSV 1,2 HIV 1,2 Epstein–Barr virus (EBV), West Nile, venereal disease research laboratory, varizella zoster, and Borrelia burgdorferi. [surgicalneurologyint.com] […] lobe on sagittal section A lumbar puncture was performed, which was negative for an infectious etiology including routine, acid-fast bacilli (AFB), and fungal cultures, cryptococcus [surgicalneurologyint.com] Arachnoiditis Repeated LP revealed persistently elevated intracranial pressures (opening pressure 50 cm H 2 0) and grew Cryptococcus gattii (VGIII). [academic.oup.com] His initial serum and CSF cryptococcal antigen were 1:128 and 1:256, respectively. A ventriculoperitoneal shunt was placed for hydrocephalus. [academic.oup.com] Retrobulbar Neuritis Gram stain and bacterial culture, India ink and latex antigen tests for Cryptococcus neoformans, CSF adenosine deaminase (ADA) for tuberculosis and TPHA ( Treponema pallidum [sajhivmed.org.za]
