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27 Possible Causes for Cryptorchidism, Wide Space Between the First and Second Toe

  • Down Syndrome

    RESULTS: Cryptorchidism was observed in 27.5% of the patients (95CI 15.98-42.96).[ncbi.nlm.nih.gov] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[doi.org]

  • Dubowitz Syndrome

    Cleft palate may occur as well as hypospadias, cryptorchidism in affected males, and mild limb defects.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Further findings include hyperactivity, eczema, cryptorchidism in the affected males, and brachy-clinodactyly of the fifth fingers.[ncbi.nlm.nih.gov]

  • Russell-Silver Syndrome

    […] retardation Normal head circumference Triangular face Fifth finger clinodactyly Normal psychomotor development Supportive criteria Short arm length Limb length asymmetry Cryptorchidism[en.wikibooks.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Cryptorchidism requiring orchiopexy should be referred for proper hormonal and surgical management.[symptoma.com]

  • Ring Chromosome 10

    Clinical features included development retardation, short stature, mild mental retardation and cryptorchidism. He had a history of photohypersensitivity.[eurekamag.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Here we report a 2.5 years old patient with a cleft lip, club foot, mental retardation and cryptorchidism.[docksci.com]

  • Kleiner Holmes Syndrome

    Related symptoms: Autosomal recessive inheritance Intellectual disability Cryptorchidism Cognitive impairment Brachydactyly SOURCES: OMIM DOID EFO MESH UMLS MONDO GARD More[mendelian.co] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov] […] patients had one or more associated anomalies such as congenital anterolateral tibial bowing and polydactyly in three, translocation of chromosome 2 : 13 associated with cryptorchidism[jkoa.org]

  • Seckel Syndrome

    Symptoms include: intellectual disability (more than half of the patients have an IQ below 50) microcephaly sometimes pancytopenia (low blood counts) cryptorchidism low birth[en.wikipedia.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] ., cryptorchidism).[medical-dictionary.thefreedictionary.com]

  • Craniofrontonasal Dysplasia

    Abnormality of the rib cage Axillary pterygia Bifid nasal tip Brachycephaly Broad hallux Cleft upper lip Congenital pseudoarthrosis of the clavicle Coronal craniosynostosis Cryptorchidism[familydiagnosis.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] 0003187 Broad hallux Broad big toe Wide big toe [ more ] 0010055 Cleft palate Cleft roof of mouth 0000175 Cleft upper lip Harelip 0000204 Coronal craniosynostosis 0004440 Cryptorchidism[rarediseases.info.nih.gov]

  • Atelosteogenesis Type 2

    Psychomotor delay; seizures; cardiovascular anomalies, including aortic and pulmonary stenosis and septal defects; and genitourinary anomalies, including absent kidney and cryptorchidism[musculoskeletalkey.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Meningomyelocele

    Uterine or vaginal anomalies can be seen in affected females instead of cryptorchidism.[alliedacademies.org] space between first and second toes 11. ability to assume unusual positions Intracranial hemorrhage interventions 1. observation of increased intracranial pressure 2. head[quizlet.com] Ferrara P, Rossodivita A, Ruggiero A, Pulitano S, Tortorolo L, Salvaggio E: Cryptorchidism associated with meningomyelocele. J Paediatr Child Health 1998;34:44–46.[karger.com]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Intellectual disability with autistic features, macrocephaly, dysmorphic features, urogenital anomalies (hypospadia, cryptorchidism), cutaneous syndactyly and precocious puberty[mendelian.co] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] Cryptorchidism was present in 4 of 6 males, suggesting hypogonadism.[genome.jp]

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