Cup Ear: Causes & Reasons

Possible Causes for Cup Ear

Facial properties include prominent narrow chin, open mouth, cupped ears with protruding lobes, broad nasal bridge with rounded nasal tip, and wide set eyes. [mowatwilson.org]

ear Cup-shaped ears Simple, cup-shaped ears [ more ] 0000378 Downslanted palpebral fissures Downward slanting of the opening between the eyelids 0000494 Drooling Dribbling [rarediseases.info.nih.gov]

Autosomal dominant inheritance 0000006 Broad eyebrow Broad eyebrows Flared eyebrow Increased vertical height of eyebrow Increased vertical thickness of eyebrow [ more ] 0011229 Cupped [rarediseases.info.nih.gov]

Genee-Wiedemann Syndrome

ear ; Downslanted palpebral fissures ; Ectropion ; Eyelid coloboma ; Growth delay ; Hypoplasia of the radius ; Hypoplasia of the ulna ; Low-set ears ; Malar flattening ; [mousephenotype.org]

Showing of 39 | 80%-99% of people have these symptoms Abnormal dermatoglyphics Abnormal fingerprints 0007477 Cupped ear Cup-shaped ears Simple, cup-shaped ears [ more ] 0000378 [rarediseases.info.nih.gov]

ears, lower lid ectropion, and symmetrical postaxial limb deficiencies with absence of the fifth digital ray and ulnar hypoplasia. [orpha.net]

Renpenning Syndrome

[…] malformation Cupped ear Hearing impairment Macrotia Protruding ear Growth abnormality Short stature IMPORTANT NOTE: NIH does not independently verify information submitted [ncbi.nlm.nih.gov]

ears. [malacards.org]

ears, and short philtrum. [ncbi.nlm.nih.gov]

Pitt-Hopkins Syndrome

The dysmorphism consists of a large beaked nose, cup-shaped ears with broad helices, a wide mouth, Cupid's bow upper lip, wide and shallow palate and broad or clubbed fingertips [ncbi.nlm.nih.gov]

Facial dysmorphism - Enophthalmos, thin eyebrows, a large beaked nose with flared nostrils, broad cup-shaped ears, a fleshy and Cupid's bow appearance of the upper lip, a [symptoma.com]

ears In addition to all of these characteristic symptoms of the disorder, the following are also common symptoms: Gastrointestinal problems, such as constipation Unusually [patientworthy.com]

Kabuki Syndrome

ears; and (4) persistent fingertip pads. [ncbi.nlm.nih.gov]

ears. [flipper.diff.org]

[…] following: (1) arched and broad eyebrows with the lateral third displaying notching or sparseness; (2) short columella with depressed nasal tip; (3) large, prominent or cupped [ncbi.nlm.nih.gov]

CHARGE Syndrome

Low-set, cupped ears.  Occasional droopy eyelids. Prominent bridge on the nose.  Prominent forehead. Undersized jaw. [sense.org.uk]

This is especially so when otolaryngologists are seeing dysmorphic patients with cranial nerve dysfunction or low, cup-shaped ears (Figure 1). [hindawi.com]

Ear anomalies (95-100%) include low-set lop or cup-shaped outer ear with deficient cartilage of the outer pinna and a triangular concha, middle ear ossicle malformations, [orpha.net]

Levy-Hollister Syndrome

ears. [semanticscholar.org]

[…] malformation Cupped ear Mixed hearing impairment Diagnosis Ophthalmic Plast Reconstr Surg 2013 May-Jun;29(3):e67-8. doi: 10.1097/IOP.0b013e31826cb897. [ncbi.nlm.nih.gov]

ears, hearing loss, hypodontia and enamel hypoplasia, and distal limb segments anomalies. [medical-dictionary.thefreedictionary.com]

Brachyphalangy Polydactyly and Tibial Aplasia/Hypoplasia

hearing loss preauricular tags cup-shaped ears overfolded helices cleft lobules Skeletal: delayed bone age Skin Nails Hair Skin: scalp defect pterygium (elbows and knees [malacards.org]

Cup shaped ears. Aplasia of ulna, radius or humerus. Monodactyly, syndactyly, absence of multiple fingers. Ectrodactyly of the feet. [fetalultrasound.com]

Cupped ear MedGen UID: 335186 • Concept ID: C1845447 • Congenital Abnormality Laterally protruding ear that lacks antihelical folding (including absence of inferior and superior [ncbi.nlm.nih.gov]

Short Stature and Facio-Auriculo-Thoracic Malformations

Symptoms via clinical synopsis from OMIM: 57 Head And Neck Ears: low-set ears small ears cup-shaped ears overfolded helices Head And Neck Eyes: ptosis Head And Neck Mouth: [malacards.org]

The characteristic facial gestalt of PHS includes microcephaly, coarse facies, broad nasal bridge, wide mouth, fleshly lips, and cup-shaped ears. [chginc.org]

LADD syndrome is characterized by aplasia, atresia or hypoplasia of the lacrimal and salivary systems, cup-shaped ears, hearing loss, and dental and digital anomalies. [chginc.org]

15q24 Deletion Syndrome

large ears cupped ears Chest Diaphragm: diaphragmatic hernia (less common) Muscle Soft Tissue: loose connective tissue Skeletal Hands: clinodactyly brachydactyly hypoplastic [malacards.org]

Face: smooth philtrum long philtrum facial asymmetry long face microretrognathia Head And Neck Mouth: open mouth small mouth high arched palate full lower lip Head And Neck Ears [malacards.org]

Warsaw Breakage Syndrome

Name Warsaw Breakage Syndrome Synonyms - Classification developmental, genetic, neoplastic Phenotypes 2-3 toe syndactyly ; Autosomal recessive inheritance ; Clinodactyly ; Cupped [mousephenotype.org]

ears Sensorineural deafness Short neck Jugular hypoplasia Cardiac features Ventricular septal defect Tetralogy of Fallot Sketelal features Clinodactyly of the fifth fingers [en.wikipedia.org]

high arched palate, coloboma of the right optic disc, deaf-ness due to structural abnormalities of the inner ear (bilateralhypoplastic cochlea), small ventricular septal [docslide.com.br]

Acrofacial Dysostosis Type Rodríguez

Craniofacial malformations, malar hypoplasia, severe micrognathia, cleft palate, small, protruding, “cup-shaped” ears, colobomas, drooping of the lower eyelids, and ectropion [accessanesthesiology.mhmedical.com]

Ears. Hypoplastic, cup-shaped ears. Nose. Short, upturned; high columella. Limbs. [obgynkey.com]

Ears. Auricular anomalies, including overfolding of the superior helix and small, sometimes cupped ears; preauricular tags. Limbs. [obgynkey.com]

Ear Deformity

Cup Ear (Constricted or Lop) Deformity Extra cartilage (a graft taken from elsewhere) may be needed for the framework. [plasticsurgery4u.com]

Prominent Ears Prominent ears, sometimes referred to as “lop-ear” or “cup ears,” are a deformity where the ears project more than the normal distance from the skull. [kidsplastsurg.com]

Ear In a cup ear, the rim (helical rim or helix) is thick and constricted, that is, it seems too tight and inflexible for the ear, so that it looks cup-shaped, and often [earbuddies.co.uk]

Miller-Dieker Syndrome

ears, hearing loss, bilateral absence of fifth fingers, supernumerary nipples Mandibulofacial dysostosis Guion-Almeida type 610536 EFTUD2 Autosomal dominant Microcephaly, [radiologykey.com]

[…] of medial third lower lid lashes, conductive hearing loss, radial ray defects Miller postaxial acrofacial dysostosis 263750 DHODH Autosomal recessive Lower lid ectropion, cupped [radiologykey.com]

Pfeiffer-Palm-Teller Syndrome

Cupped ear Capuchin ears, Simple, cup-shaped ears, Cup-shaped ears [more] Laterally protruding ear that lacks antihelical folding (including absence of inferior and superior [rarediseases.oscar.ncsu.edu]

ear Cup-shaped ears Simple, cup-shaped ears [ more ] 0000378 Narrow palpebral fissure Small opening between the eyelids 0045025 Showing of 12 | Last updated: 2/1/2021 Find [rarediseases.info.nih.gov]

ears, and narrow palpebral fissures with epicanthal folds, and intellectual deficit. [rarediseases.info.nih.gov]

Blepharophimosis-Epicanthus Inversus-Ptosis Syndrome

ear Cup-shaped ears Simple, cup-shaped ears [ more ] 0000378 Epicanthus inversus 0000537 Female infertility 0008222 High palate Elevated palate Increased palatal height [ [rarediseases.info.nih.gov]

Abnormality of the breast 0000769 Abnormality of the hair Hair abnormality 0001595 Amenorrhea Abnormal absence of menstruation 0000141 Autosomal dominant inheritance 0000006 Cupped [rarediseases.info.nih.gov]

[…] of the hair Hair abnormality [ more ] 0001595 Abnormality of the breast 0000769 Amenorrhea Abnormal absence of menstruation 0000141 Autosomal dominant inheritance 0000006 Cupped [rarediseases.info.nih.gov]

Agenesis of Lacrimal and Salivary Glands

LADDS is an autosomal dominant syndrome characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel [geniverse.concord.org]

ears and hearing loss, in addition to dental and digital anomalies. [ashg.org]

Lacrimo-auriculo-dento-digital syndrome is characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel [genecards.org]

Congenital Aural Atresia

N. : Hereditary cup-shaped ears and the Pierre Robin syndrome. J. Med. [sonoworld.com]

13.9 Lop-Cup Ear Anomaly ; 13.10 Protruding Ear ; 13.11 Variants of the Helix and Anthelix ; 13.12 Variants of the Ear Lobe ; 13.13 Auricular Tags ; 13.14 Auricular Pits [amazon.de]

pocket ear, absence of the upper helix, absence of the tragus, clefts, lobular deformities, and cup ear deformities type 1 and 2 Second degree : Dysplasia as a cup ear deformity [radiologykey.com]

Anotia

A severely cupped ear before surgery Cup ear 10 days after surgery, stitches present A cupped upper pole and absent lower pole pre-op The reconstructed ear immediately after [earreconstruction.co.uk]

Classification There is great variety in the shape of underdeveloped ears, from a relatively minor lack of rim tissue which causes a cup deformity of the ear, through type [earreconstruction.co.uk]

N. : Hereditary cup-shaped ears and the Pierre Robin syndrome. J. Med. [sonoworld.com]

X-Linked Mandibulofacial Dysostosis

The contralateral ear in these subjects was unremarkable with the exception of IV.1 who had a small, cupped ear. [jmg.bmj.com]

This 3-year-old boy has visible cup-ear deformities. He also has branchial cleft fistulae and only one kidney. [slideplayer.com]

Esophageal atresia, hypoplasia of zygomatic complex, microcephaly, cup-shaped ears, congenital heart defect, and mental retardation--new MCA/MR syndrome in two affected sibs [humangenetik-regensburg.de]

Patau Syndrome

A mild clinical phenotype is described in a patient with duplication of 13q32-->qter and a small deletion of 18p11.32-->pter. The 8 year old white male presented with psychomotor retardation, tethered cord, soft, fleshy ears, and normal facial features except for thin lips. The karyotype was found to be 46, XY,[…] [ncbi.nlm.nih.gov]

Kidney Disease

Current guidelines recommend Na(+)-based alkali for CKD with metabolic acidosis and plasma total CO2 (PTCO2) < 22 mM. Because diets in industrialized societies are typically acid-producing, we compared base-producing fruits and vegetables with oral NaHCO3 (HCO3) regarding the primary outcome of follow-up estimated[…] [ncbi.nlm.nih.gov]

Microcephaly - Cardiomyopathy

ears. [jmg.bmj.com]

He had cup shaped ears, but no other dysmorphic features were noted. In particular, he did not have fifth finger clinodactyly or a big sandal gap. [jmg.bmj.com]

We describe another patient with microcephaly and a dilated cardiomyopathy, secondary hyperthyroidism, minor brain abnormalities, and cup shaped ears, but without any other [jmg.bmj.com]

Turner Syndrome

Turner syndrome, first described in 1938 by Henry Turner, is as loss or abnormality of the second X chromosome in at least one cell line in a phenotypic female. At birth, girls with Turner syndrome may have swollen hands and feet because of lymphedema. The blend of dysplastic or hypoplastic nails and lymphedema[…] [symptoma.com]

X-Linked Mental Retardation Type 93

Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic[…] [books.google.com]

Autosomal Dominant Mental Retardation Type 1

If a word is labeled in RED, that means that it is defined under the “Basic Genetics” tab. Check out this link, to understand some of these terms better and to gain more genetic knowledge. My child just received a diagnosis of 2q23.1 deletion/duplication disorder. What do I do next? If you have received these[…] [2q23.org]

X-Linked Syndromic Mental Retardation Type 28

REFERENCIAS BIBLIOGRÁFICAS 1. Real Academia Española. Inteligencia. Madrid: Real Academia Española; 2019. (Citado el 30 de marzo de 2020) Disponible en: http://lema.rae.es/drae2001/srv/search?id=2qlbggjrBDXX2HVuWUL7 [ Links ] 2. Sternberg RJ. Intelligence. Dialogues Clin Neurosci. 2012;14(1):19-27. [ Links ] 3. Plomin R, von[…] [scielo.org.pe]

Ververi-Brady Syndrome

[…] malformation Cupped ear Low-set ears Macrotia Growth abnormality Fetal growth restriction Short stature IMPORTANT NOTE: NIH does not independently verify information submitted [ncbi.nlm.nih.gov]

[…] malformation Cupped ear Low-set ears Macrotia Growth abnormality Fetal growth restriction Short stature [ncbi.nlm.nih.gov]

Also some presented with brachycephaly, upslanting palpebral fissures, broad nose with broad nasal tip, low-set and cup-shaped ears, and transverse palmar creases. [globalgenes.org]

Congenital Malformation of the Ear

Congenital ear anomaly NOS, Congenital malformation of ear, unspecified, Ear anomalies, CUP EAR, EAR MALFORMATION, congenital deformity of ear (diagnosis), congenital deformity [fpnotebook.com]

Congenital ear anomalies include microtia (lack of all or part of the structures that form the outer ear), prominent ears and lop/cupped ears. [rileychildrens.org]

Cup ear: Here the cartilage of almost the whole of the ear is deficient together with a deficiency of the skin. The ear does not unfurl and looks like a cup. [shortnotesinplasticsurgery.wordpress.com]

Congenital Disease

Test Catalog Invitae Congenital Disorders of Glycosylation Panel Test description The Invitae Congenital Disorders of Glycosylation Panel analyzes up to 103 genes that are associated with congenital disorders of glycosylation (CDGs). This test is useful for the diagnosis of patients in whom a congenital disorder of[…] [invitae.com]