Possible Causes for Cushingoid Facies Iatrogenic Cushing Syndrome On physical examination she had cushingoid facies, truncal obesity, drumstick limbs, and paper-thin skin with striae. [thelancet.com] Figures Figure 1: Cushingoid facies of the 1st affected child Figure 2: Cushingoid facies of the 2nd affected child Figure 3: Picture of intranasal steroid administered References [panafrican-med-journal.com] Cushing Syndrome At the age of 5 months, after approx. 3 months of dexamethasone therapy, the patient presented with cushingoid facies, nephrocalcinosis and failure to grow. [ncbi.nlm.nih.gov] On examination, the child had Cushingoid facies with trunkal obesity. Blood pressure was normal. [ncbi.nlm.nih.gov] She had a three month history of progressive Cushingoid facies, acne and irritability. [doi.org] Pituitary Cushing Syndrome General examination revealed high blood glucose and blood pressure and a Cushingoid facies. [ncbi.nlm.nih.gov] Small-Cell Carcinoma of the Lung Metastasis from small-cell carcinoma of the lung (SCCL) has most frequently been found in the lymph nodes, bones, brain, and liver. We have reported a case of metastatic SCCL located in the uveal layer of both eyes (choroidal in one and iridic in the other), an extremely rare occurrence. [ncbi.nlm.nih.gov] Recurrent Small-Cell Carcinoma of the Lung There is no standard therapy for relapsed small cell lung cancer (rSCLC). We evaluated the efficacy and toxicity of a new triplet consisting of irinotecan (100 mg/m(2) Days 1 and 15 q28), cisplatin (40 mg/m(2) Days 1 and 15 q28) and mitomycin (6 mg/m(2) d1 q28) administered to a maximum of 6 cycles in individuals[…] [ncbi.nlm.nih.gov] Paraneoplastic Syndrome Question: When should an ophthalmologist consider the diagnosis of a paraneoplastic syndrome? 2 Question with answers: When should an ophthalmologist consider the diagnosis of a paraneoplastic syndrome? “In terms of afferent symptoms, an unexplained, painless, progressive vision loss is typical. With retinal[…] [neuro-ophthalmology.stanford.edu] Pituitary Adenoma Pituitary adenomas are tumors that occur in the pituitary gland. Pituitary adenomas are generally divided into three categories dependent upon their biological functioning: benign adenoma, invasive adenoma, and carcinomas. Most adenomas are benign, approximately 35% are invasive and just 0.1% to 0.2% are carcinomas.[…] [en.wikipedia.org] Islet Cell Tumor There are two general types of islet cell tumors of the pancreas; functional and nonfunctional. Both types can increase hormone levels, but the hormones released by functional islet cell tumors produce symptoms, whereas those released by nonfunctional tumors do not. Symptoms that eventually develop with[…] [sharecare.com] Mauriac Syndrome Physical examination revealed very short stature, overweight, Cushingoid facies, and hepatomegaly. [revistagastroenterologiamexico.org] It is associated with poor control of type-1 diabetes mellitus (T1DM) in adolescents, and may present as obesity, hepatomegaly, cushingoid facies and elevated transaminases [snpedia.com] Adrenal Cushing Syndrome Mixed corticomedullary adrenal tumours (MCMT) are rare. We describe the second reported case of a male patient presenting with hypertension and Cushing syndrome with MCMT. A man aged 48 years presented with hypertension and signs of Cushing syndrome. 24-hour urine cortisol was elevated, with detectable[…] [ncbi.nlm.nih.gov] Adrenocortical Carcinoma Abstract Adrenocortical carcinoma is a rare, aggressive malignancy that features a correspondingly poor prognosis. The disease accounts for 0.2% of all malignancies and despite multimodal therapies, its prognosis remains poor, with a mean survival of © 2014 S. Karger AG, Basel Background Adrenocortical carcinoma[…] [karger.com] Nelson Syndrome Endocr Pathol. 2010 Dec;21(4):227-9. doi: 10.1007/s12022-010-9138-3. Author information 1 Department of Laboratory Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. Abstract MGMT expression in tumors has been correlated with response to treatment with temozolomide therapy. Few medical[…] [ncbi.nlm.nih.gov] Adrenal Cortex Hormone This is a low power image of the adrenal gland (Masson's Trichrome stain). Can you identify the capsule, adrenal cortex and component regions: zona glomerulosa, zona fasciculata and zona reticularis and adrenal medulla. Adrenal Gland These are a pair of glands, one associated with each kidney. They have an inner[…] [histology.leeds.ac.uk] Nephrotic Syndrome Type 2 The most common side effect of prolonged prednisone therapy for the nephrotic syndrome include Cushingoid facies and habitus, behavior changes, hypertension, growth retardation [clinicaladvisor.com] facies, and hirsutism can result from prolonged steroid therapy. [dovepress.com] facies and habitus, delayed growth, and increased risk of infection. [clinicaladvisor.com] Secondary Hypereosinophilic Syndrome He presented with cushingoid facies, knee arthritis, violet streaks on the abdomen and darkened skin with erythematous and papular lesions on his face, limbs and trunk (Figure [htct.com.br] Primary Hypereosinophilic Syndrome He presented with cushingoid facies, knee arthritis, violet streaks on the abdomen and darkened skin with erythematous and papular lesions on his face, limbs and trunk (Figure [htct.com.br] Nephrotic Syndrome Type 8 The most common side effect of prolonged prednisone therapy for the nephrotic syndrome include Cushingoid facies and habitus, behavior changes, hypertension, growth retardation [clinicaladvisor.com] facies, and hirsutism can result from prolonged steroid therapy. [dovepress.com] facies and habitus, delayed growth, and increased risk of infection. [clinicaladvisor.com] Hypokalemic Nephropathy There were no cushingoid facies, buffalo hump, or abdominal striae. Vital signs were temperature 98.6 degrees, pulse 95, respiratory rate 14, blood pressure 128/73. [casesjournal.biomedcentral.com] Ophthalmic Steroid facies and poor growth. [pediatrics.aappublications.org] By 2.5 months post–steroid use, his Cushingoid facies resolved, and a low-dose, 1 mcg adrenocoricotropic hormone (ACTH) stimulation test was performed, revealing a baseline [pediatrics.aappublications.org] Once our patient was weaned to physiologic dosing of steroids, his growth improved dramatically and his Cushingoid features resolved. [pediatrics.aappublications.org] Muscular Dystrophy Weight gain and cushingoid facies are common adverse effects after 6 to 18 mo. Risk of vertebral compression and long bone fractures also is increased. [msdmanuals.com] Steroid Atrophy facies. [healio.com] Complications included generalized pallor upon injection, localized hypertrichosis, reversible subcutaneous atrophy, ecchymosis, cessation of growth, increase of body hair, and cushingoid [healio.com] Ectopic ACTH Syndrome A 39-year-old woman who presented with typical Cushingoid appearance (moon facies, central obesity, purpura) was admitted to our hospital because of pulmonary infection. [ncbi.nlm.nih.gov] […] features of central obesity, moon facies, cervical fat pad, purple striae, and hirsutism. [mdmag.com] […] malignant tumors (eg, small-cell lung carcinoma) than in the more indolent neuroendocrine tumors (eg, carcinoid) in which ectopic ACTH syndrome often presents with the typical cushingoid [mdmag.com] Linear IgA Dermatosis Five years after onset of the condition, she presented glaucoma, arterial hypertension, osteoporosis, and Cushingoid facies as side effects of prolonged corticosteroid therapy [scielo.br] Senior-Boichis Syndrome Other side effects of steroid therapy in our study included cushingoid facies. [academic.oup.com] facies 6/20 Table 1. [academic.oup.com] facies 6/20 During the 6 month period of cyclophosphamide treatment, 10 out of 20 patients (50%) were able to successfully stop steroids for >2 weeks and thus were no longer [academic.oup.com] Elephantiasis CLINICAL CASES Copyright © 2002 EDIZIONI MINERVA MEDICA language: Italian Filariasis-like elephantiasis of the inferior limb in a woman with a cushingoid facies: adrenal pathology [minervamedica.it] Chronic Acquired Pure Red Cell Aplasia Long-term use of high-dose prednisone results in significant toxicity, including some combination of growth retardation, cushingoid facies, buffalo hump, osteoporosis, aseptic [patient-help.com] ACTH-Independent Cushing Syndrome The Cushingoid appearance includes * rounded face (moon facies), truncal obesity (fat especially around the waist), "buffalo hump" (increased fatty tissue in the supraclavicular [drdaiter.com] Malignant Neoplasm of the Thymus Case 2 A 23-year-old female presented with Cushingoid facies. [ijpmonline.org] Duchenne Muscular Dystrophy Weight gain and cushingoid facies are common adverse effects after 6 to 18 months. Risk of vertebral compression and long bone fractures also is increased. [msdmanuals.com] Autoimmune Hepatitis Kunkel, in 1950, and Bearn, in 1956, described other features of the disease, including hepatosplenomegaly, jaundice, acne, hirsutism, cushingoid facies, pigmented abdominal [emedicine.medscape.com]
