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255 Possible Causes for Cushing's Disease, Headache, Hypernatremia

  • Empty Sella Syndrome

    Otolaryngologists frequently encounter patients with complaints of headaches.[ncbi.nlm.nih.gov] We studied a patient who presented with a global hypothalamic dysfunction including adipsic hypernatremia.[ncbi.nlm.nih.gov] This study was performed to determine the effect of ESS on immediate and long-term biochemical outcome after pituitary surgery for Cushing's disease (CD).[ncbi.nlm.nih.gov]

  • Adrenocortical Carcinoma

    Conn syndrome ( mineralcorticoid excess) is marked by high blood pressure which can result in headache and hypokalemia (low serum potassium, which can in turn produce muscle[en.wikipedia.org] Six months after surgery, she showed signs of hypertension recurrence accompanied by hypokalemia (serum potassium: 2.9 mEq/l) and hypernatremia (serum sodium: 150 mEq/l).[casesjournal.biomedcentral.com] This was suggestive of primary adrenal disease as cortisol levels normally suppress to less than 50% of basal levels in pituitary driven Cushing’s disease.[pmj.bmj.com]

  • Diabetes Insipidus

    She presented with visual disturbance and headache followed by thirst, nocturia and polyuria. A visual field defect was present.[ncbi.nlm.nih.gov] Hypernatremia was corrected by scheduled water intake with desmopressin administration.[ncbi.nlm.nih.gov] […] syndrome E24.0 Pituitary-dependent Cushing's disease E24.1 Nelson's syndrome E24.2 Drug-induced Cushing's syndrome E24.3 Ectopic ACTH syndrome E24.4 Alcohol-induced pseudo-Cushing's[icd10data.com]

  • Chronic Alcoholism

    In the event of discontinuation of alcohol drinking, the patient exhibits anxiety, anger, sweating, nausea, headaches, limb tremor, in the most severe cases, hallucinations[tadalafilgen.com] The symptoms of acute alcoholism are headache , tiredness, hangover, anxiety, and other physical signs.[epainassist.com] The immediate neurological problems that may result from a period of heavy drinking are trouble sleeping and headaches.[searidgealcoholrehab.com]

  • Pituitary Neoplasm

    The clinical presentation mainly depends on hormone-secreting effects, but a headache may often be the only symptom.[symptoma.com] […] poor peripheral vision) excessive thirst and frequent urination growth failure delayed or premature puberty nausea dry skin constipation fatigue low or high blood pressure hypernatremia[pituitary.mgh.harvard.edu] A 52-year-old woman developed recurrent hypercortisolism 3 yr after successful surgical treatment of Cushing's disease.[ncbi.nlm.nih.gov]

  • Intracranial Hypertension

    Headache. 1992 Feb;32(2):84-94. Review. PubMed PMID: 1551793. Askmark H, Lundberg PO, Olsson S. Drug-related headache . Headache. 1989 Jul;29(7):441-4.[headachejournal.org] In a recently published analysis of pooled data from three prospective clinical trials, continuous infusion of HTS correlated with serum hypernatremia and reduced ICH burden[ncbi.nlm.nih.gov] Associations A variety of conditions are known to be associated with IIH including: endocrine adrenal insufficiency Cushing disease hypoparathyroidism hypothyroidism excessive[radiopaedia.org]

  • Mineralocorticoid

    Eplerenone was well tolerated; headache was the most common adverse event for patients in any group.[ncbi.nlm.nih.gov] THE syndrome of hypertension, mild edema, hypernatremia and hypokalemic alkalosis associated with an adrenocortical adenoma secreting excessive amounts of aldosterone was[nejm.org] The more severe mineralocorticoid manifestations in the ectopic ACTH syndrome compared to pituitary Cushing's disease have been attributed to hypersecretion of 11-deoxycorticosterone[ncbi.nlm.nih.gov]

  • Panhypopituitarism

    She had headache, vision disturbance, polyuria, polydipsia, hypernatremia, diabetes insipidus and a pituitary lesion with findings compatible with apoplexy.[ncbi.nlm.nih.gov] A 34-yr-old woman with primary APS presented with polyuria, polydipsia, hypernatremia and impaired vision.[ncbi.nlm.nih.gov] Also look for evidence of hormonal hypersecretion due to a large functioning adenoma, such as signs of Cushing disease, acromegaly, or galactorrhea. Kim SY.[emedicine.medscape.com]

  • Adrenal Insufficiency

    The patient experienced severe headaches due to acute adrenal insufficiency without changes in the size of the cyst.[ncbi.nlm.nih.gov] Its release will lead to hypernatremia and hypokalemia, once stimulated by ACTH, elevated potassium levels, and/or the renin-angiotensin-aldosterone system (RAAS).[pharmacytimes.com] Most tumors causing Cushing’s disease are small, thus most Cushing’s disease patients retain sufficient ACTH production following surgery.[csrf.net]

  • Syndrome of Inappropriate Antidiuretic Hormone Secretion

    Due to continuing symptoms of hyponatremia including headaches, nausea, vomiting, and paresthesias after reinitiation of fluid restriction and salt tablets, tolvaptan was[ncbi.nlm.nih.gov] An unrecognized complication is the development of severe hypernatremia as a result of strict fluid restriction and concomitant excessive free water excretion from prolonged[ncbi.nlm.nih.gov] […] syndrome ( E24.- ) Nelson's syndrome ( E24.1 ) overproduction of ACTH not associated with Cushing's disease ( E27.0 ) overproduction of pituitary ACTH ( E24.0 ) overproduction[icd10data.com]

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