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508 Possible Causes for Cushing's Disease, Hyperpigmentation

  • ACTH-Secreting Pituitary Adenoma

    Over the ensuing years, the patient developed Nelson's syndrome with hyperpigmentation and markedly elevated ACTH levels.[] Cushing’s Disease vs.[] […] affective disorder Bipolar disorder 0007302 Cardiomyopathy Disease of the heart muscle 0001638 Cataract Clouding of the lens of the eye Cloudy lens [ more ] 0000518 Generalized hyperpigmentation[]

  • Acne Vulgaris

    Post-inflammatory hyperpigmentation after acne can be as troublesome as the acne itself.[] This may occur in testosterone replacement therapy, abuse of anabolic steroids, Cushing's disease or in virilising tumours in women, such as arrhenoblastoma.[] Polycystic ovarian syndrome, anovulation, Cushing's disease, and androgen-secreting tumors cause these sudden changes.[]

  • Nelson Syndrome

    Furthermore, hyperpigmentation of scars, the buccal mucosa, and even tongue might be observed.[] The short-term follow-up results in patients with Cushing* disease, Nelson syndrome and chromophobe adenoma are very encouraging.[] Clinical management of persistent adrenocorticotropin hormone (ACTH) excess in Nelson syndrome (NS) and Cushing disease (CD) remains a challenge.[]

  • Cushing's Disease

    The disease manifests with signs of CS (truncal and facial obesity and signs of hypercatabolism) as well as skin hyperpigmentation and/or neurological complications in some[] If Cushing's disease remains untreated it may be fatal.[] The symptoms of Cushing's disease are similar to those seen in other causes of Cushing's syndrome.[]

  • Polyostotic Fibrous Dysplasia

    It is characterized by deformities and fractures of the bones, endocrine abnormalities including early puberty, and skin hyperpigmentation Fibrous dysplasia of bone affecting[] These include sexual precocity, espeCially in females (3, 4), goiter and/or hyperthyroidisr:n (4, 5), growth hormone (GH) hypersecretion (6), Cushing' disease (7) and ac-celerated[] INTRODUCTION: Fibrous dysplasia (FD) is a disorder involving either one (monostotic) or several bones (polyostotic FD [PFD] and sometimes is associated with cafe- au -lait hyperpigmentation[]

  • Acanthosis Nigricans

    He was referred to our polyclinic by endocrinologist because of progressive hyperpigmentation marked on his face and oral mucosa.[] It is associated with obesity, endocrinopathies (insulin resistance, diabetes mellitus, Cushing disease and acromegaly) and visceral malignancies.[] , insulin-resistant diabetes, or Cushing's disease.[]

  • Adenoma

    […] cardiomegaly, heat intolerance, weight gain ACTH ( 20%) Cushing's disease : central obesity (moon facies, buffalo hump), thin skin with striae, hirsutism Nelson's syndrome : hyperpigmentation[] ’s disease.[] […] complex [ edit ] Carney complex (CNC), also known as LAMB syndrome [20] and NAME syndrome [20] is an autosomal dominant condition comprising myxomas of the heart and skin, hyperpigmentation[]

  • Chronic Alcoholism

    Skin changes due to liver disease Hyperpigmentation Skin darkening ( hyperpigmentation ) around the eyes, mouth and on the legs may be associated with chronic liver disease[]

  • ACTH-Independent Cushing Syndrome

    Furthermore, certain patient groups may demonstrate additional or atypical clinical features depending on the etiology of Cushing syndrome 6 : patients with Cushing disease: hyperpigmentation[] disease and Cushing syndrome.[] Other effects include hyperpigmentation secondary to high serum levels of ACTH, resulting in a characteristic brown or bronze coloring of the mucous membranes, hair and skin[]

  • Cushing Syndrome

    Hyperpigmentation and proximal myopathy were frequent, while central obesity was uncommon.[] Cushing's disease. 1,2,4,5 It's important to note that Cushing's disease is a specific form of Cushing's syndrome, so the two terms are not interchangeable. 5 CUSHING'S SYNDROME[] Clinical presentation included asthenia, insomnia, hypertension, acne, and hyperpigmentation developing in a period of two months.[]

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