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701 Possible Causes for Cushing's Disease, Hypokalemia

  • ACTH-Secreting Pituitary Adenoma

    Depressivity Depression 0000716 Diabetes mellitus 0000819 Fatigue Tired Tiredness [ more ] 0012378 Generalized hirsutism Excessive hairiness over body 0002230 Hypertension 0000822 Hypokalemia[] Cushing’s Disease vs.[] May also cause hypertension and hypokalemia due to increase in 11-deoxycorticosterone, and hirsutism due to increased androgens.[]

  • Adrenocortical Carcinoma

    A 65-year-old seemingly well male patient was referred to our clinic under the suspicion of hyperaldosteronism due to hypertension combined with hypokalemia.[] This was suggestive of primary adrenal disease as cortisol levels normally suppress to less than 50% of basal levels in pituitary driven Cushing’s disease.[] […] beta-estradiol (serum, only in men and postmenopausal women) Mineralocorticoid excess potassium (serum) aldosterone/renin ratio (only in patients with arterial hypertension and/or hypokalemia[]

  • Chronic Alcoholism

    The presence of thyrotoxicosis and hypokalemia does not always indicate a diagnosis of TPP.[] Recent reports have emphasized the occurrence of a myopathy in chronic alcoholism associated with hypokalemia.[] Laboratory data revealed hypokalemia (2.2 mmol/L), elevated creatine kinase (7282 U/L), metabolic alkalosis and reduced urine potassium, albumin, and total protein.[]

  • Cushing's Disease

    Tw o also demonstrated personality changes, hypertension and hypokalemia, the last of these being rarely reported in patients with Cushing's disease.[] The symptoms of Cushing's disease are similar to those seen in other causes of Cushing's syndrome.[] Ectopic ACTH secretion was initially suspected on the basis of very high cortisoluria and ACTH concentrations, severe hypokalemia, a lung hypermetabolic lesion and a normal[]

  • Licorice Ingestion

    Hypokalemia and hypertension associated with use of liquorice flavoured chewing gum. BMJ. 1997; 314: 731-732. Farese RV Jr, Biglieri EG, et al.[] Disease, hypercalcemia, and diabetes mellitus.[] A 54-year-old man was admitted to hospital with acute rhabdomyolysis and myoglobinuria due to hypokalemia.[]

  • Multiple Endocrine Neoplasia

    In the patients with hypertension, new onset diabetes and hypokalemia, the Cushing syndrome and pheochromocytoma should always be ruled out.[] Corticotropin-releasing hormone (CRH) loading test ruled out Cushing's disease and supported the diagnosis of EAS.[] The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME.[]

  • Adrenogenital Syndrome

    […] congenital adrenal hyperplasia that leads to a decrease in adrenal androgen synthesis and an increase in aldosterone, causing renal reabsorption of sodium, hypertension, and hypokalemia[] The right adrenal gland was significantly wider in the patients with Cushing's disease and AGS than in control subjects.[] Genitalia and Intersexuality •Androgen Insensitivity Syndrome •Cystic Fibrosis •Denys-Drash Syndrome •Failure to Thrive •Familial Glucocorticoid Deficiency •Hyperkalemia •Hypokalemia[]

  • Iatrogenic Cushing's Disease

    The weakness in patients with CS is aggravated by associated hypokalemia which is due to increased mineralocorticoid activity.[] Iatrogenic Cushing's disease (iatrogenic Cushing's syndrome) is the most common cause of cushingoid symptoms.[] 8mg dexamethasone test (pituitary tumors more likely to suppress cortisol 50%), CRH stimulation (pituitary tumors more likely to stimulate cortisol post CRH), presence of hypokalemia[]

  • Relapsed Small Cell Lung Cancer

    Grade 3/4 adverse events ( 5% incidence) included anemia, thrombocytopenia, neutropenia/leukopenia, diarrhea, fatigue, dehydration, and hypokalemia for topotecan; and thrombocytopenia[] For the patients with limited disease and who submitted in treatment the median survival is 15-20 months and for those with extensive disease the survival reduced in 7-11[] Most were grade 1/2; single episodes of grade 3 febrile neutropenia, grade 3 hypomagnesemia, and grade 4 hypokalemia occurred.[]

  • Hypoaldosteronism

    A 51-year-old Japanese woman with hypokalemia due to distal renal tubular acidosis associated with Sjögren's syndrome exhibited a decreased plasma aldosterone level despite[] I have cyclic Cushing’s Disease.[] He had severe hypokalemia with hypertension and was diagnosed with pseudoaldosteronism.[]

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