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21 Possible Causes for Cysteine and Disulfide Bonds in Hair Decreased, Thick Wiry Hair

  • Hidrotic Ectodermal Dysplasia

    Analytical biochemical investigations in hidrotic ectodermal dysplasia have demonstrated that the abnormal hair exhibits lower levels of disulfide bonds and cysteine, which[symptoma.com] What to be alert for in the history --Abnormally thick and wiry hair in infancy --Progressive alopecia with age --Progressively dystrophic nails --Palmoplantar changes --Painful[dermatologyadvisor.com] Early signs and symptoms generally begin in infancy and may include nail abnormalities and sparse scalp hair that is wiry, brittle, patchy and pale.[rarediseases.info.nih.gov]

  • Craniofrontonasal Dysplasia

    wiry hair, and occasionally cleft lip and/or palate.[genedx.com] wiry hair with orbital asymmetry and strabismus. 5 The extracranial features include multiple skeletal malformations, such as sloping shoulders, dysplastic clavicles, thoracic[ncbi.nlm.nih.gov] , wiry, and curly hair at 2-3 months Defects in formation of toes and fingers, broad fingers and toes, curved last finger Increased webbing in between the fingers and toes[dovemed.com]

    Missing: Cysteine and Disulfide Bonds in Hair Decreased
  • Trichotillomania

    hairs they describe as being different from the rest (eg, "wiry," "thick," "stubby," "kinky," or of a darker color). 19 Unfortunately, the trauma of pulling, which damages[web.archive.org] hairs they describe as being different from the rest (eg, “wiry,” “thick,” “stubby,” “kinky,” or of a darker color). 19 Unfortunately, the trauma of pulling, which damages[dx.doi.org] Often, children with TTM will scrutinize and then touch or stroke the hair before pulling. 16, 18 Hairs are usually pulled out individually, and often patients will select[web.archive.org]

    Missing: Cysteine and Disulfide Bonds in Hair Decreased
  • Zosteriform Lentiginosis

    […] in naevus skin esp on scalp – hair often dark, thick and wiry What are the associations of CMN on the skin?[brainscape.com] […] childhood Surface often becomes thick/rugose or warty - esp on scalp; simulates cutis verticis gyrata Often also develop nodules within larger naevi Can be increased terminal hair[brainscape.com]

    Missing: Cysteine and Disulfide Bonds in Hair Decreased
  • CAMFAK Syndrome

    This is associated with a decrease in the ratio of strong to weak disulfide bonds within the hair shafts.[dermaamin.com] […] demonstrates reduced levels of cysteine and cystine in hair shaft proteins.[dermaamin.com] […] the hair), trichorrhexis nodosa-like defects, and ribboning Hair shafts are brittle because of a reduction of high-sulfur matrix proteins, and amino acid analysis of the hair[dermaamin.com]

    Missing: Thick Wiry Hair
  • Gorlin-Chaudhry-Moss Syndrome

    In infancy, scalp hair is wiry, brittle, patchy, and pale; progressive hair loss may lead to total alopecia by puberty.[vivavoceoralmedicineradiology.com] The nails may be milky white in early childhood; they gradually become dystrophic, thick, and distally separated from the nail bed.[vivavoceoralmedicineradiology.com]

    Missing: Cysteine and Disulfide Bonds in Hair Decreased
  • Congenital Ankyloblepharon

    (hypotrichosis) Can be brittle, coarse or wiry with pili torti Patchy alopecia (lack of hair) Eyebrows, eyelashes and body hair may also be sparse or absent.[nfed.org] Affected individuals usually have normal sweating capacity and typically normal teeth, but they classically have pale, brittle, slow-growing, and wiry hair with progressive[cancertherapyadvisor.com] Nails Small Hyperconvex Thick Hyper-ridging Missing Eyes Eyelid fusion (ankyloblepharon) Corneal erosions Blepharitis (chronic inflammation of the eyelid) Conjunctivitis(pink[nfed.org]

    Missing: Cysteine and Disulfide Bonds in Hair Decreased
  • Rapp-Hodgkin Syndrome

    (hypotrichosis) Can be brittle, coarse or wiry with pili torti Patchy alopecia (lack of hair) Eyebrows, eyelashes and body hair may also be sparse or absent.[nfed.org] Nails Small Hyperconvex Thick Hyper-ridging Missing Eyes Eyelid fusion (ankyloblepharon) Corneal erosions Blepharitis (chronic inflammation of the eyelid) Conjunctivitis(pink[nfed.org] […] in AEC may mimic epidermolysis bullosa (EB) or a collodian baby (skin that resembles a yellow, tight and shiny film) or dried collodion (sausage skin) Hair Sparse, fine hair[nfed.org]

    Missing: Cysteine and Disulfide Bonds in Hair Decreased
  • Ectodermal Dysplasia

    Affected individuals usually have normal sweating capacity and typically normal teeth, but they classically have pale, brittle, slow-growing, and wiry hair with progressive[clinicaladvisor.com] […] alopecia; thick, small, and discolored nails; palmoplantar hyperkeratosis; thickening and darkening of the skin at the elbows, knees, over the joints, axillae, areolae, and[clinicaladvisor.com]

    Missing: Cysteine and Disulfide Bonds in Hair Decreased
  • Dermo-Odonto Dysplasia

    […] in the hair may be absent –Decreased cysteine and disulfide bonds in the hair –Skin biopsy of the scalp reveals a reduced number of dystrophic hair follicles with thickened[dermatologyadvisor.com] What to be alert for in the history –Abnormally thick and wiry hair in infancy –Progressive alopecia with age –Progressively dystrophic nails –Palmoplantar changes –Painful[dermatologyadvisor.com] […] with disorganized fibrillar structure and reduced birefringence on polarized light –Hair shafts are abnormal and may be square with longitudinal grooves and twisting –Pigment[dermatologyadvisor.com]

Further symptoms