Cytoplasmic Vacuolization Causes & Reasons

Neu Starten

Ad Html Headline Ad Text Headline

Ad Label Ad Html Description Ad Text Description

Determine your risk of now. Restart test

Caution! In case of an emergency:

Seek emergency care

Hi, I'm Symptoma.

Cytoplasmic Vacuolization Symptom Checker: Possible causes include Hibernoma. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

For full functionality of this site it is necessary to enable JavaScript.

How to enable JavaScript?

Possible Causes

Hibernoma

Pathologic findings include sheets of multivacuolated cells with centrally placed nuclei and numerous tiny surrounding cytoplasmic vacuoles overlying bony trabeculae. [ncbi.nlm.nih.gov]

Cytology[edit] The fine needle aspiration smears show small, round, brown fat-like cells, with uniform, small cytoplasmic vacuoles and regular, small, round nuclei. [en.wikipedia.org]

vacuoles and regular, small, round nuclei Delicate branching capillaries Variable mature fat cells (Cancer 2001;93:206) Negative stains CD34 (usually), p53 (usually, but [pathologyoutlines.com]

Show info

Lipid Cell Tumor of the Ovary

(oil red-O stain) Two atypical mitotic figures Images hosted on other servers: H&E, Oil Red O (fig 4) Diffuse sheets of large polygonal cells with vacuolated cytoplasm, vesicular [pathologyoutlines.com]

A) High power Hematoxylin and Eosin view demonstrating nests of polygonal cells with eosinophilic cytoplasm. Focal cytoplasmic vacuolization is present. [journals.sagepub.com]

cytoplasm Positive stains Fat stains on fresh / frozen tissue, vimentin (75%), keratin (50%) and actin (30%) Electron microscopy description Increased smooth endoplasmic [pathologyoutlines.com]

Show info

Hereditary Mucoepithelial Dysplasia

Papanicolaou smears show lack of epithelial cell maturation, poikilocytosis, anisocytosis, large paranuclear cytoplasmic vacuoles, and cytoplasmic strand-shaped inclusions [ncbi.nlm.nih.gov]

Vaginal, oral, and urinary cytological smears show a lack of epithelial cell maturation, large paranuclear cytoplasmic vacuoles, and cytoplasmic strand-shaped inclusions. [ncbi.nlm.nih.gov]

Ultrastructural features include a paucity of desmosomes, intercellular accumulations of amorphous material, cytoplasmic vacuoles, and paranuclear lesions with strands of [ncbi.nlm.nih.gov]

Show info

Sertoli Cell Tumor of the Testis

Nine tumors had cytoplasmic vacuoles, and three of four that were investigated stained for intracytoplasmic glycogen. [ncbi.nlm.nih.gov]

Large cytoplasmic vacuoles were prominent in 26 tumors. Nuclear atypicality was absent or mild in 54 cases, moderate in 4 cases, and marked in 2 cases. [thedoctorsdoctor.com]

Fine needle aspiration (FNA) cytologic smears showed large polygonal tumor cells with abundant finely granular or vacuolated eosinophilic cytoplasm and eccentric nuclei with [ncbi.nlm.nih.gov]

Show info

Familial Visceral Myopathy

Histologic abnormalities primarily involved smooth muscle and included marked nuclear enlargement and irregularity, interstitial fibrosis, and cytoplasmic vacuolation. [ncbi.nlm.nih.gov]

vacuoles, marked nuclear enlargement and irregularity and interstitial fibrosis ( Am J Surg Pathol 1987;11:846 ) May have segmental hypoganglionosis at transitional zone [pathologyoutlines.com]

Microscopic (histologic) description Visceral myopathy: vacuolar degeneration with swelling and loss of muscle cells, fibrosis of outer longitudinal muscle layer; other cases show cytoplasmic [pathologyoutlines.com]

Show info

Hilar Cell Tumor of the Ovary

Leydig cell cytoplasm is densely eosinophilic and finely granular with small lipid-containing cytoplasmic vacuoles. [jemds.com]

cytoplasm Enlarged, hyperchromatic, bizarre nuclei Advertisement [pathologyoutlines.com]

and small punctuate cytoplasmic vacuoles. [emedicine.medscape.com]

Show info

Acute Erythroblastic Leukemia

Morphology The leukemic red cells are frequently bizarre with extreme dysplastic features including: giant forms, multinucleation, cytoplasmic vacuolization, cytoplasmic buds [wiki.clinicalflow.com]

Blast cells were identified as belonging to the erythroblastic line by their ultrastructural features: glycogen deposits, lipidic vacuoles, cytoplasmic ferritin molecules [ncbi.nlm.nih.gov]

Morphology: The leukemic red cells are frequently bizarre with extreme dysplastic features including: giant forms, multinucleation, cytoplasmic vacuolization, cytoplasmic [med-ed.virginia.edu]

Show info

Rhabdomyoma of the Myocardium

- Purkinje cell tumour ( Foamy myocardial transformation) - Hamartoma (no cytoplasmic vacuolation). Pinterest -(drsampurna) [histopathology-india.net]

However, the cytoplasmic vacuoles tend to be central, with myofibrils at the periphery. [cttr.org]

Cytoplasmic vacuoles, some with erythrocytes (arrows). Heart. Valvular heart disease. 1.0 1.1 Castillo, JG.; Silvay, G. (Mar 2010). [librepathology.org]

Show info

Benign Interstitial Cell Tumor of the Testis

Synonyms interstitial cell tumour LM cytoplasmic vacuolization, cytoplasm -- clear to eosinophilic, /- Reinke crystals (cylindrical crystalloid -- eosinophilic cytoplasmic [librepathology.org]

Cytoplasm vacuolated in appearence (HE stain 10 ). [sjkdt.org]

Microscopically, hexagonally shaped cells with granular, eosinophilic cytoplasm containing lipid vacuoles are seen. [health.am]

Show info

Hypocupremia

Bone marrow aspirate smears demonstrated multiple clear cytoplasmic vacuoles in proerythroblasts, also plasma cells containing hemosiderin pigment were present (Figure 1). [haematologica.org]

Many of the early granulocytic precursors (blasts and promyelocytes) contained multiple small cytoplasmic vacuoles. [ncbi.nlm.nih.gov]

(A) Bone marrow aspirate smears demonstrated multiple clear cytoplasmic vacuoles in promyelocytes (left panels) and proerythroblasts (right panels) from Case 1 (bottom panels [haematologica.org]

Show info

Beta-Mannosidosis

There were no detectable oligosaccharides or cytoplasmic vacuolation in the liver or spleen. [ncbi.nlm.nih.gov]

Many remaining cells in myelin-deficient regions were characterized by dark, vacuolated cytoplasm. [ncbi.nlm.nih.gov]

Electron microscopy showed cytoplasmic vacuolation. [ncbi.nlm.nih.gov]

Show info

Hemangioblastoma

Microscopically, the neoplasm was seen to be composed of vascular channels associated with foamy stromal cells, containing clear cytoplasmic vacuoles. [ncbi.nlm.nih.gov]

Tumor was composed of numerous capillaries and stromal cells with cytoplasmic vacuolization. [ncbi.nlm.nih.gov]

vacuolated cytoplasm. [diagnosticpathology.biomedcentral.com]

Show info

Acute Undifferentiated Leukemia

The cells have mild to moderate amount of cytoplasm with multiple cytoplasmic vacuoles (MGG-Giemsa stain 100X, A). [omicsonline.org]

vacuolation consistent with a Burkitt's-like L3 acute lymphoblastic transformation. [ncbi.nlm.nih.gov]

Blast cells were identified as belonging to the erythroblastic line by their ultrastructural features: glycogen deposits, lipidic vacuoles, cytoplasmic ferritin molecules [ncbi.nlm.nih.gov]

Show info

Pleomorphic Liposarcoma

vacuole or vacuoles Must be sharply defined Must indent and distort nucleus May be focal or widespread S100 may highlight lipoblasts May contain cytoplasmic eosinophilic [surgpathcriteria.stanford.edu]

vacuoles Sarcomatous component contains atypical spindled, round, and pleomorphic tumor cells Numerous mono- and multinucleated tumor giant cells High degree of nuclear atypia [basicmedicalkey.com]

Fine needle aspiration cytology smears displayed prominent arborizing vasculature with numerous lipoblasts with well-defined vacuolated cytoplasm, indenting the nuclei. [ncbi.nlm.nih.gov]

Show info

Epithelioid Hemangioendothelioma

Pathologic examination revealed a pleuropulmonary neoplasm with cytologic features including round to oval epithelioid cells with frequent cytoplasmic vacuoles. [ncbi.nlm.nih.gov]

It is histologically typified by epithelioid or spindle cells present singly or in cords or clusters, many with cytoplasmic vacuoles that can contain intraluminal erythrocytes [ncbi.nlm.nih.gov]

They are composed of rounded or slightly spindled eosinophilic endothelial cells with rounded nuclei and prominent cytoplasmic vacuolization. [ncbi.nlm.nih.gov]

Show info

Benign Hemangioendothelioma

The neoplastic cells showed no nuclear atypia and contained variably prominent eosinophilic cytoplasm with or without cytoplasmic vacuoles which was reminiscent of endothelial [wjso.biomedcentral.com]

The lesion exhibited primitive vasoformation characterized by the presence of cytoplasmic vacuoles. Occasional mitotic figures were seen. [ispub.com]

The vacuolization of cytoplasm is characteristic, presenting attempts to form a primitive vascular lumen. The nuclei are round with prominent nucleoli. [synapse.koreamed.org]

Show info

Pseudopyogenic Granuloma

Other notable features occurring in several endothelial cells are cytoplasmic vacuolation and the acquisition in the subnuclear zone of dense bodies associated with fine actin-like [ncbi.nlm.nih.gov]

vacuoles. [uscapknowledgehub.org]

Careful scrutiny will frequently reveal "autolumination", whereby an erythrocyte is contained within a clear paranuclear vacuole in the cytoplasm of a spindled endothelial [diagnosticpathology.biomedcentral.com]

Show info

Leydig Cell Tumor of the Testis

Synonyms interstitial cell tumour LM cytoplasmic vacuolization, cytoplasm -- clear to eosinophilic, /- Reinke crystals (cylindrical crystalloid -- eosinophilic cytoplasmic [librepathology.org]

Cytoplasm vacuolated in appearence (HE stain 10 ). [sjkdt.org]

[…] mass or lipid droplets, 3) Numerous mitochondria with occasional tubular cristae, 4) Numerous lipid vacuoles. [ncbi.nlm.nih.gov]

Show info

Rhinoscleroma

cytoplasmic vacuoles and small centrally or peripherally located nuclei (Mikulicz cells). [ijpmonline.org]

Mikulicz cells are large foamy phagocytes with peripheral nuclei and multiple cytoplasmic vacuoles that contain Klebsiella bacilli (5, 6). [archcid.com]

Mikulicz cells are clear cytoplasm vacuolated histiocytes containing the bacillus. Factors involved in transforming histiocytes into Mikulicz cells are unknown 9. [scielo.br]

Show info

Well-Differentiated Liposarcoma

A 0.6-mm fine-needle aspiration biopsy (FNAB) of a paratesticular lump showed many spindle and polygonal atypical cells with numerous cytoplasmic vacuoles. [ncbi.nlm.nih.gov]

vacuole(s) that indent and distort nucleus Frequently contains fibrous or myxoid areas Collagen may be fine or coarse Frequently extends between adjacent lipocytes at edge [surgpathcriteria.stanford.edu]

[…] and numerous lipid vacuoles or granular eosinophilic cytoplasm. [ncbi.nlm.nih.gov]

Show info

Cholesterol Ester Storage Disease

Approximately 20% of lymphocytes demonstrated between 1 and 7 cytoplasmic vacuoles (panels A-C; May–Grünwald–Giemsa stain). [ashpublications.org]

Show info

Phosphine Poisoning

Fine isomorphic cytoplasmic vacuoles were observed in 36 cases (94.7%). These vacuoles were distributed uniformly in all hepatic zones in the majority (75%) of cases. [ncbi.nlm.nih.gov]

This study reveals that the main histopathologic findings of fatal phosphine poisoning in the liver are fine cytoplasmic vacuolization of hepatocytes and sinusoidal congestion [ncbi.nlm.nih.gov]

Show info

Pleomorphic Xanthoastrocytoma

Histological examination revealed cellular pleomorphism and cytoplasmic vacuolation consistent with PXA, but no mitoses, necrosis, or endothelial proliferation. [ncbi.nlm.nih.gov]

Finally, the possibility of an anaplastic (pilocytic) astrocytoma was also given consideration but this appeared unlikely due to focal cytoplasmic tumor cell vacuolization [path.upmc.edu]

vacuolization (on frozen sections demonstrated to represent lipidization), the finding of sparse EGBs complemented by the presence of necrotic changes and a significant proliferative [path.upmc.edu]

Show info

Acute Erythremia

Cytoplasmic vacuoles are variably present and can be prominent in pronormoblasts (Figure 3, A). [archivesofpathology.org]

(A) Bone marrow aspirate smear showing large primitive cells with vacuolated cytoplasm. [jcp.bmj.com]

Morphology: The leukemic red cells are frequently bizarre with extreme dysplastic features including: giant forms, multinucleation, cytoplasmic vacuolization, cytoplasmic [med-ed.virginia.edu]

Show info

Atrophic Vaginitis

Parabasal cells also may contain cytoplasmic vacuoles and are known as foam cells. In premenopausal & younger woman, vaginal cells are mature. i.e superficial. [slideshare.net]

These cells are characterized by the high nuclear cytoplasmic ratio, round nucleus, and basophilic cytoplasm. They are uniform in size and shape. [slideshare.net]

Show info

Paget Disease of the Breast

cytoplasm, and they are considered benign counterparts of Paget cells. [emedicine.com]

[…] rarely in supernumerary nipples on the mild line and apocrine bearing areas. [6] Like Paget cells of both mammary and extramammary sites, Toker cells contain prominent clear (vacuolated [emedicine.com]

Show info

Adenovirus Infection

cytoplasm Adenovirus immunostain Electron microscopy images Images hosted on other servers: Figure 1 Figure 2 Fig 1: intranuclear inclusions with (inset) regular pattern [pathologyoutlines.com]

2015;66:467 ) Microscopic (histologic) images Images hosted on other servers: Figures C-E Infected cells with irregular amphophilic nuclei Cells have eccentric nuclei and vacuolated [pathologyoutlines.com]

Show info

Extraskeletal Myxoid Chondrosarcoma

Microscopically, EMC shows strands and cords of relatively small cells with acidophilic cytoplasm that are occasionally vacuolated. [ncbi.nlm.nih.gov]

Cells were mainly polygonal shaped with round to indented nuclei, uniform chromatin, displaying intranuclear inclusions, grooves, and eosinophilic to finely vacuolated cytoplasm [ncbi.nlm.nih.gov]

Based on the pathologic appearance of the cells and IHC features, the diagnosis of extraskeletal myxoid chondrosarcoma with prominent cytoplasmic vacuolization was established [cureus.com]

Show info

Alcohol Abuse

vacuoles also due to copper deficiency, hematogones, lipid storage diseases, lipid granulomas, monocytes, Mott cells Back to top [pathologyoutlines.com]

Images hosted on other servers : Marrow plasma cell has dense aggregate of iron Iron laden organelle in upper cell may correspond to microscopic plaque Differential diagnosis Cytoplasmic [pathologyoutlines.com]

Show info

Refractory Anemia with Excess Blasts in Transformation

[…] of erythroid precursors Nucleus lags behind cytoplasm Ring sideroblasts 5 iron granules encircling 1/3 of the nucleus Usually either many or none Cytoplasmic vacuoles Also [surgpathcriteria.stanford.edu]

The erythroids are left shifted and show dysplastic features such as prominent cytoplasmic vacuolation, binucleation, nuclear to cytoplasmic dyssynchrony and increased number [iupui.edu]

vacuolization  Howell-Jolly bodies Multinucleation Ring sideroblasts 35. [slideshare.net]

Show info

⚕ Symptoma®️ is a digital health assistant but no replacement for the opinion and judgement of medical professionals. By using this website you fully understand and accept that it shall not be used as a diagnostic system for decision-making. It absolutely must not be used to obtain, replace or overrule a clinical diagnosis by a healthcare professional. It is always for the medical professional to make the final diagnosis. The medical information provided on this website is of a general nature and can not substitute for the advice of a medical professional (for example, a qualified doctor or physician)! Information from the internet could and should NOT be solely used to offer or render a medical opinion or otherwise engage in the practice of medicine.