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110 Possible Causes for Darier's Sign

  • Urticaria Pigmentosa

    Darier's sign was positive. Serum triptase levels were elevated. Diagnosis of mastocytosis was confirmed by pathohistology.[] Widespread slate-grey patches and erythematous hyperpigmented plaques were observed with a positive Darier's sign.[] Based on the clinical presentation of skin lesions, presence of pruritus and positive Darier's sign, cutaneous mastocytosis was diagnosed; 24-hour pH-metry revealed an increased[]

  • Systemic Mastocytosis

    Darier sign How is mastocytosis diagnosed? Cutaneous mastocytosis is usually diagnosed by its clinical appearance and positive Darier sign .[] sign.[] sign .[]

  • Indolent Systemic Mastocytosis

    Darier sign How is mastocytosis diagnosed? Cutaneous mastocytosis is usually diagnosed by its clinical appearance and positive Darier sign .[] It is commonly characterized by multiple hyperpigmented macular or maculopapular lesions that become urticarial when rubbed or scratched (Darier’s sign).[] This is known as Darier's sign. It's usually possible to confirm a diagnosis by carrying out a biopsy , where a small skin sample is taken and checked for mast cells.[]

  • Primary Anetoderma

    Anetoderma with positive Darier's sign. Our Dermatol Online. 2017;8(1):53-55.[] Darier s sign might reflect abnormal mechanosensitivity of mast cells in certain skin lesions [ 9 ].[] Positive Darier s sign on anetodermic lesions was the only point for diagnosis which is pathognomonic for mastocytosis.[]

  • Dermatologic Disorder

    Up to 5% of normal patients may exhibit this sign, which is a form of physical urticaria. Darier sign refers to rapid swelling of a lesion when stroked.[] Rubbing the lesion causes the development of a wheal and erythema (Darier sign).[] The Darier sign of urticaria pigmentosa is characterized by urticaria and erythema upon rubbing, scratching, or stroking the affected skin.[]

  • Scabies

    We report a misleading case of a 5-month-old child, who presented with pruritic brown-red macules of the trunk showing a positive Darier's sign, suggestive of an urticaria[] sign, suggestive of urticaria pigmentosa.[] We report two misleading cases of young infants (10- and 12-month-old infants) who presented with pruritic brown-red lesions on their trunks and showing a positive Darier's[]

  • T-cell Acute Lymphoblastic Leukemia

    Leukemia cutis: Darier’s sign in a neonate with acute lymphoblastic leukemia. J Am Acad Dermatol 1996; 34(2): 375-78. 7. Pui CH. Acute lymphoblastic lymphoma.[]

  • Leiomyomatosis

    Pseudo-Darier's sign can be seen, and when rubbed, the leiomyoma may twitch or fasciculate, mimicking the Darier's sign of mastocytosis. Figure 1. Leiomyomas.[] sign may be present.[] […] mammillary muscle of the nipple ( genital leiomyoma ), the smooth muscle of blood vessels ( angioleiomyoma ) and the lung ( pulmonary lymphangioleiomyomatosis ). [5] A pseudo- Darier[]

  • Congenital Smooth Muscle Hamartoma

    Congenital smooth muscle hamartoma presenting with an unusual pseudo-Darier's sign. Clinical and Experimental Dermatology , 31 (1), 148-149.[] The lesion is most frequent in the lumbosacral area (67% [10/15]) and a positive pseudo-Darier's sign is present in 80% (12/15) of patients.[] We describe a case of congenital smooth muscle hamartoma with hypertrichosis and pseudo-Darier's sign, and suggest that it is a clinicohistopathological entity distinct from[]

  • Angioma Serpiginosum

    However, Darier’s sign was negative. The rest of the cutaneous and systemic examination was unremarkable.[]

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