Treatment with antihistamines and corticosteroids may be necessary for symptom control, and educational information could be useful in limiting Darier's sign elicitation and
[frontiersin.org]
sign, namely, the enlargement and swelling (rarely blistering in the first months of life) of lesions after induced or spontaneous rubbing.
[frontiersin.org]
Due to the hyperproduction of histamine, children with CM experience cutaneous manifestations, including mainly pruritus, erythema, red dermographism, flushing, hives, and Darier's
[frontiersin.org]