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737 Possible Causes for Dark Skin Pigmentation, Echogenic Kidneys with Thick-Walled Pelvises, Palmar Nevi

  • Costello Syndrome

    Pigmented lesions have previously been reported as nevi in the literature though no biopsies have been reported.[ncbi.nlm.nih.gov] A 2-year-old Japanese boy presented with a 'coarse' face, curly hair and loose skin of the dorsal aspect of the hands and feet with dark pigmentation.[ncbi.nlm.nih.gov] We conclude that thick, loose skin on the dorsal aspects of hands and feet and deep palmar and plantar creases are cardinal manifestations of Costello syndrome and benign[ncbi.nlm.nih.gov]

  • Liver Cirrhosis

    A compelling clinical picture required, in the absence of other explanations, the presence of at least 4 of the following: spider nevi, scleral icterus, palmar erythema, ascites[dx.doi.org] The same bile pigment, bilirubin, which is responsible for the yellow skin tones of jaundice can turn urine dark.[chp.edu] Jaundice is a yellow discoloration of the skin and whites of the eyes due to abnormally high levels of bilirubin (bile pigment) in the bloodstream.[stanfordchildrens.org]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises
  • Skin Cancer

    […] or lower legs Often on palmar, plantar and subungual areas (acral melanoma) Major risk factors for melanoma include intermittent high exposure to sunlight (ie—sunbathing)[ncbi.nlm.nih.gov] Malignant Melanoma Melanoma has its beginnings in melanocytes, the skin cells that produce the dark, protective pigment called melanin which makes the skin tan.[reliantmedicalgroup.org] skin pigmentation, and children with many other conditions. 67, 71, 72 The benefits of vitamin D sufficiency in adults include improved bone health, prevention of fractures[doi.org]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises
  • Primary Biliary Cirrhosis

    , palmar erythema, ascites, temporal and proximal muscle wasting, and peripheral edema American Liver Foundation.[emedicine.medscape.com] Hyperpigmentation Cholestasis increases production of the dark pigment, melanin, which is found in the skin. The darkening of the skin is called hyperpigmentation.[emedicinehealth.com] Palmar erythema Ascites Temporal and proximal muscle wasting Peripheral edema See Clinical Presentation for more detail.[emedicine.com]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises
  • Sunburn

    The body protects itself from this harmful radiation by accelerating the production of melanin, the dark pigment that gives skin its normal color.[medicalnewstoday.com] A dark pigment called melanin. It’s produced by cells in our skin, and serves to absorb any UV light and transform it into heat.[elitedaily.com] Melanin is the skin's protective coloring (pigment).[medlineplus.gov]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises Palmar Nevi
  • Multiple Hamartoma Syndrome

    Furthermore, shiny palmar keratoses with central dells are also present.[en.wikipedia.org] At birth or in childhood, classic features of Cowden's include pigmented genital lesions, lipomas, epidermal nevi, and cafe-au-lait spots.[en.wikipedia.org]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises
  • Polycystic Ovary Syndrome

    The pigmentation and skin texture changes can also appear under your arms and around the vulva. 5. Your belly is getting bigger and you don't know why.[self.com] Laser therapy destroys hair by targeting the pigment (melanin) in the hair follicle and is ideally suited for dark-haired, light-skinned individuals.[obgyn.ucla.edu] "It's a velvety, dark discoloration that doesn't wash off," explains Siddiqui.[self.com]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises Palmar Nevi
  • Varicose Veins

    Sometimes you will notice a dark pigment forming on the lower legs or a congested purple appearance of the feet at the end of the day.[palmclinic.co.nz] Other symptoms can include ankle swelling, restlessness in the legs, cramp, itching, or a red rash (‘varicose eczema’) on the skin of the legs.[palmclinic.co.nz]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises Palmar Nevi
  • Malignant Melanoma

    Melanoma begins in melanocytes, the skin cells that produce the dark protective pigment called melanin that makes the skin tan.[torontodermatologycentre.com] Melanoma comes from skin cells called melanocytes. These cells produce melanin, the dark pigment that gives skin its color.[my.clevelandclinic.org] Melanin is the dark pigment that gives the skin its natural colour. Melanin is made in the skin by pigment cells called melanocytes.[britishskinfoundation.org.uk]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises Palmar Nevi
  • Addison's Disease

    Even people with dark skin can develop excessive pigmentation, although the change may be harder to recognize.[merckmanuals.com] ) skin, and dark freckling.[encyclopedia.com] Corticotropin also stimulates melanin production, so the skin and the lining of the mouth often develop a dark pigmentation.[merckmanuals.com]

    Missing: Echogenic Kidneys with Thick-Walled Pelvises Palmar Nevi