Dark Urine: Causes & Reasons

Possible Causes for Dark Urine

Urinary urobilinogen Other significant findings Prehepatic jaundice Dark ↑↑ Normal Normal ↑↑ (no darkening of urine, but dark urine may occur in the case of hemoglobinuria [amboss.com]

Patients with medical jaundice will have yellowing of the skin, without dark urine or light-coloured stools. [healthxchange.sg]

Symptoms of obstructive jaundice include the typical yellowing of jaundice as well as dark urine, pale feces, and itching. Also known as post-hepatic jaundice. [medicinenet.com]

Cholestasis

urine Inability to digest certain foods Itching Nausea or vomiting Pain in the right upper part of the abdomen Yellow skin or eyes Blood tests may show that you have elevated [medlineplus.gov]

It can also be accompanied by: jaundice pale stools dark urine abdominal pain nausea See your doctor if you have itching in pregnancy. [healthline.com]

Anabolic steroids Birth control pills Chlorpromazine Cimetidine Estradiol Imipramine Prochlorperazine Terbinafine Tolbutamide Symptoms may include: Clay-colored or white stools Dark [medlineplus.gov]

Viral Hepatitis

Symptoms Symptoms generally include fever, weakness, fatigue, loss of appetite, nausea, joint aches and pains, vomiting, and jaundice (yellowish eyes and skin, dark urine [hepvic.org.au]

urine Jaundice (yellowing of the skin and eyes) Hepatitis B and hepatitis C infections can lead to chronic hepatitis infections, in which case individuals will remain infected [dph.georgia.gov]

In the icteric phase, the patients develop jaundice, gastrointestinal disturbance, dark urine, gray-colored stools, right upper quadrant pain, and hepatomegaly. [symptoma.com]

Ascending Cholangitis

It can also be accompanied by: jaundice pale stools dark urine abdominal pain nausea See your doctor if you have itching in pregnancy. [healthline.com]

Both types of cholestasis result in the same symptoms: jaundice, which is a yellowing of your skin and the white of your eyes dark urine light-colored stool pain in your abdomen [healthline.com]

Rhabdomyolysis

Dark yellow urine is a sign of dehydration. [askdoctork.com]

As no erythrocytes in the microscopic examination of the urine and hemoglobinuria were present, myoglobinuria due to rhabdomyolysis was the most probable cause of dark urine [ncbi.nlm.nih.gov]

Symptoms of rhabdomyolysis include dark urine, muscle weakness and fatigue. Statins are the most commonly used drugs for prevention and management of dyslipidemia. [ncbi.nlm.nih.gov]

Drug-Induced Toxic Hepatitis

Later, there may be jaundice and dark urine and an enlarged and tender liver. When the offending medication is withdrawn, symptoms may gradually subside. [hepatitiscentral.com]

Some of the common symptoms are: nausea vomiting headache anorexia jaundice clay color stools dark urine hepatomegaly Diagnosis Diagnosis is typically made through a physical [medical-dictionary.thefreedictionary.com]

urine Diarrhea Fatigue Fever Headache Jaundice Loss of appetite Nausea and vomiting Rash White or clay-colored stools Exams and Tests You will have blood tests to check liver [m.ufhealth.org]

Isoniazid Hepatitis

These include any of the following: unexplained anorexia, nausea, vomiting, dark urine, icterus, rash, persistent paresthesias of the hands and feet, persistant fatigue, weakness [rxwiki.com]

urine for several days 1 146 107 Liver transplant 29 Eczema Rare concurrent alcohol consumption Fatigue, nausea for 2 weeks then icterus, dark urine and jaundice for several [cdc.gov]

Dark colored urine can be a sign of liver problems. [uofmhealth.org]

Paroxysmal Rhabdomyolysis

Patients suffered generalized weakness, inability to walk, myalgia, muscle weakness, and dark urine. All patients appeared healthy in between episodes. [cags.org.ae]

The urine becomes dark brown, gives positive reaction for orthotoluidine and shows no RBCs. [jpgmonline.com]

If you notice dark “Coca Cola” colored urine after an intense workout, get checked out by a healthcare provider immediately. [healthcentral.com]

Acute Exertional Rhabdomyolysis

After four years of no symptoms, one day after a basketball game he began to have general myalgies and dark urine. [revistanefrologia.com]

Myoglobin in the urine causes your urine to become dark in color similar to cola. [bsmpg.com]

He initially thought his soreness was a normal consequence of his workout, but became concerned when he noticed the dark urine. [emdocs.net]

Acute Hepatic Porphyria

You could also have: Dark urine Sensitive skin Belly pain Nausea Seizures An attack usually starts with severe stomach pain and can last for days. [webmd.com]

/reddish urine, hyponatremia Muscle weakness, numbness, respiratory failure Confusion, anxiety, seizures, hallucinations, fatigue Blistering lesions, erosions or ulcers of [alnylam.com]

Consider AIP if typical clinical features are seen in the absence of other causes (e.g., unexplained severe abdominal pain accompanied by muscle weakness and dark urine). [amboss.com]

Idiosyncratic Drug-Induced Liver Injury

urine Diarrhea Fatigue Fever Headache Jaundice Loss of appetite Nausea and vomiting Rash White or clay-colored stools Exams and Tests You will have blood tests to check liver [mountsinai.org]

Patients should be advised to promptly report any new onset symptoms such as yellowing of their eyes, abdominal pain / discomfort, nausea / vomiting, itching, or dark urine [utahgastroblog.com]

Glomerulonephritis

The patient may report gross hematuria, dark or tea-colored urine, or have been referred from clinic for blood found on urinalysis. [emedicine.medscape.com]

When To Call A Professional Call your doctor if you or your child is putting out less urine then normal or if urine looks bloody or abnormally dark. [drugs.com]

This is in contrast to another type of glomerulonephritis, post-streptococcal glomerulonephritis, where the blood-stained or dark urine episode does not occur until about [mydr.com.au]

Hepatitis B

Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. [youtube.com]

Symptoms include fatigue, jaundice, nausea, vomiting, dark urine, light stools. Diagnosis is by blood test. [medicinenet.com]

Most people do not experience any symptoms during acute infection but may have symptoms, such as yellowing of the skin and eyes (jaundice), dark urine, extreme fatigue, nausea [nvic.org]

Autoimmune Hepatitis

The patient suffers from non-specific symptoms such as fatigue, dark urine, and discoloration of stools, upper abdominal discomfort or skin rashes. [drfalkpharma.com]

urine. [txliver.com]

urine Diagnosing Autoimmune Hepatitis Your hepatologist will first perform a medical history and a physical exam, and will listen to a description of your symptoms. [virginiamason.org]

Paroxysmal Cold Hemoglobinuria

He was admitted because of dark urine after exposure to cold air. [ncbi.nlm.nih.gov]

[…] anemia myelodysplasia acute leukemia Diagnosis often made during pregnancy Presentation Symptoms/physical exam episodic dark urine with first urine of the day caused by hemoglobin [medbullets.com]

Systemic symptoms include the passage of dark urine, severe pain in the back and legs, headache, vomiting, diarrhea, and moderate reticulocytosis. [medical-dictionary.thefreedictionary.com]

Drug-Induced Cholestatic Hepatitis

The typical presentation of symptoms includes nausea, fatigue and pruritus followed by dark urine and jaundice. [livertox.nih.gov]

Dark urine [ citation needed ] Causes [ edit ] Possible causes: pregnancy androgens birth control pills antibiotics (such as TMP/SMX) abdominal mass (e.g. cancer ) biliary [en.wikipedia.org]

Symptoms of both types of cholestasis include jaundice, pale and fatty stools, dark urine, and intense itching over the skin. [medical-dictionary.thefreedictionary.com]

Intrahepatic Cholestasis

The skin and whites of the eyes look yellow, the skin itches, urine is dark, and stools may become light-colored and smell foul. [merckmanuals.com]

Associated manifestations include fatigue, loss of appetite, dark urine and pale stools. Hepatomegaly is also a common finding. [orpha.net]

Symptoms Jaundice, dark urine, light-colored stools, and generalized itchiness are characteristic symptoms of cholestasis. [merckmanuals.com]

Autoimmune Hemolytic Anemia

The macrophages then proceed in destroying the “tagged” RBCs producing the typical hemolytic by-products which cause some of the clinically relevant signs such as dark urine [pedclerk.bsd.uchicago.edu]

A 41-year-old woman with Crohn's disease presented to our emergency room (ER) with dark urine, dizziness, and shortness of breath. [ncbi.nlm.nih.gov]

The disease is characterized by symptoms due to the anemia including fatigue, exertional dyspnea, and, more rarely, jaundice and dark urine in case of severe hemolysis. [orpha.net]

Extrahepatic Cholestasis

It can also be accompanied by: jaundice pale stools dark urine abdominal pain nausea See your doctor if you have itching in pregnancy. [healthline.com]

Pale stools and dark urine - pale stools occur as no bilirubin reaches the gastrointestinal tract and dark urine results from reflux of conjugated bilirubin into blood which [patient.info]

The biochemical derangement is reinforced by clinical symptoms and signs: pale stool - no bilirubin reaching gastrointestinal tract for conversion to stercobilin dark orange [gpnotebook.co.uk]

Blackwater Fever

Progressive clearance of his urine is shown, from dark brown on admission (T0, or zero hour) to yellow 42 hours after admission (T42). [nejm.org]

urine. [histopathology-india.net]

[…] noun mass noun A severe form of malaria in which blood cells are rapidly destroyed, resulting in dark urine. [en.oxforddictionaries.com]

Hepatitis A

The highly contagious liver disease includes symptoms like fever, fatigue, nausea, dark urine, and yellowing skin. [whcuradio.com]

urine Usually asymptomatic in children, more severe illness in elderly and pregnant women, usually resolves in 1 month Complications Liver failure is rare Diagnosis Test [sti.guidelines.org.au]

Symptoms of the disease include mild fever, loss of appetite, nausea, fatigue, vomiting, diarrhea, abdominal pain and dark urine and jaundice. [nj.com]

Cholestasis of Pregnancy

Dark Urine and/or Pale Stools (grayish in color) Preterm Labor Jaundice Other symptoms may include: Right Upper Quadrant Pain Nausea Fatigue or Exhaustion Loss of Appetite [liverfoundation.org]

The following signs and symptoms may be present in cases of cholestasis of pregnancy: intense itching, especially on the palms of the hands and soles of the feet dark urine [medicalnewstoday.com]

Other symptoms include dark urine, steatorrhea and, less commonly, jaundice. [rcm.org.uk]

Choledocholithiasis

Endoscopic cholangiography(gold standard) : CBD stone 여부 및 위치 확인, 치료도 가능 → 총수담관담석증(Choledocholithiasis, CBD stone, 온쓸개관돌증) 증상 : Obstructive jaundice ① Jaundice, pruritus, dark [m.blog.naver.com]

Patients may also experience clay-colored stools and dark urine. [jamanetwork.com]

Dark urine. Symptoms associated with Pancreatitis. Charcot's Triad:[edit] Clasically seen in common-bile-duct-stone. [en.wikibooks.org]

Paroxysmal Nocturnal Hemoglobinuria

Two years after disease onset, while pancytopenia remained stable, occurrence of morning dark urine led to found a paroxysmal nocturnal hemoglobinuria clone. [ncbi.nlm.nih.gov]

In reality the condition is present all the time and not everyone experiences dark urine. [pnhleeds.co.uk]

Bile Duct Disease

urine Diagnosis of a Bile Duct Condition If your doctor suspects you may have a bile duct blockage, tests will be done to look at the extent of the blockage and determine [fhdigestivecaretampa.com]

Dark urine When bilirubin levels in the blood get high, it can also come out in the urine and turn it dark. [cancer.org]

[…] patients often experience: Jaundice, yellowing of the skin or eyes Stools that are clay-colored Fever Itching Loss of appetite; Pain in the upper right side of the abdomen Dark [fhdigestivecaretampa.com]

Chronic Cholecystitis

Jaundice, dark urine, light-colored stools, and generalized itchiness are characteristic symptoms of cholestasis. [msdmanuals.com]

Stones lodged in the common bile duct can cause symptoms that are similar to those produced by stones that lodge in the gallbladder, but they may also cause: Jaundice Dark [hopkinsmedicine.org]

The skin and whites of the eyes look yellow, the skin itches, urine is dark, and stools may become light-colored and smell foul. [msdmanuals.com]

Toxic Hepatitis

Four weeks later; he developed dark urine and pale stools, associated with asthenia and right hypochondrial pain. [ncbi.nlm.nih.gov]

Later, there may be jaundice and dark urine and an enlarged and tender liver. When the offending medication is withdrawn, symptoms may gradually subside. [hepatitiscentral.com]

urine. [health-factbook.com]

Hepatitis C

If symptoms do happen, they can include: Fever Fatigue (feeling very tired) Not feeling hungry Feeling nauseous, or sick to your stomach Vomiting Dark-colored urine (pee) [kidneyfund.org]

If you do, they may include: Belly pain Clay-colored poop Dark urine Fatigue Fever Jaundice (yellow tint to your skin or eyes) Joint pain Poor appetite Nausea Vomiting Symptoms [webmd.com]

[…] eyes and skin, as well as dark urine) Joint pain Loss of appetite Nausea Stomach pain Vomiting Symptoms usually last for 2 to 12 weeks. [webmd.com]

Biliary Atresia

Because bile can’t flow normally, it collects in the liver causing severe liver damage Symptoms include yellow skin, dark urine, pale stool, and a larger liver To treat this [msdmanuals.com]

Infants are jaundiced and often have dark urine (containing conjugated bilirubin), acholic stools, and hepatosplenomegaly. [merckmanuals.com]

Symptoms of biliary atresia include: Dark-colored urine Pale-colored stool The baby's skin takes on a yellowish color (jaundice) The baby's liver gets larger Once your baby [msdmanuals.com]

Hepatobiliary Disorder

Common clinical presentations were jaundice in 32 (71%), dark urine in 19 (42%), fever in 13 (29%), failure to thrive in 7 (16%), splenomegaly in 21 (47%) and hepatomegaly [tropicalgastro.com]

They include: yellowing of the skin (jaundice) dark urine joint pain a loss of appetite pain in the abdomen liver enlargement acute liver failure nausea vomiting fatigue fever [healthline.com]

The common clinical features were jaundice in 32 (71%), dark urine in 19 (.42%), fever in 13 (29%), failure to thrive in 7 (16%), splenomegaly in 21 (47%) and hepatomegaly [tropicalgastro.com]