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1,887 Possible Causes for Dark Urine, Direct Bilirubin Increased, Fatigue, Fever

  • Primary Biliary Cirrhosis

    We report the case of a 52-year old woman who initially presented to the gastroenterology department for extreme fatigue, pale stools, dark urine and pruritus.[ncbi.nlm.nih.gov] Fatigue is a significant problem in approximately 50% of primary biliary cirrhosis (PBC) patients, with 20% of all patients experiencing significant or life-altering fatigue[ncbi.nlm.nih.gov] In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena.[ncbi.nlm.nih.gov] Jaundice, dark urine, and darkening of the skin exposed to the sun occur as the liver disease progresses.[healthcentral.com]

  • Hepatitis A

    urine, jaundice , fever, abdominal pain[en.wikipedia.org] Most adults with hepatitis A have symptoms, including fatigue, low appetite, stomach pain, nausea, and jaundice, that usually resolve within 2 months of infection; most children[cdc.gov] Symptoms may include fatigue, fever, nausea, myalgia, jaundice and pruritus. Recurrence and chronic hepatitis do not usually occur.[symptoma.com] A 25-year-old Japanese man was admitted with general malaise and fever, which had developed 12 days after coming back to Japan from Indonesia.[ncbi.nlm.nih.gov]

  • Primary Sclerosing Cholangitis

    Dark urine, as a result of excretion of bile by-products into urine Anorexia, fatigue, malaise (general discomfort or unease), and abdominal pain Nutritional deficiencies,[dovemed.com] Moreover, they experienced less itch (p 0.03) and less Fatigue (p 0.03) and had better Cognitive Abilities (p 0.04) as assessed by the PBC-40 and PBC-27 questionnaires.[ncbi.nlm.nih.gov] The pathogen was supposedly acquired during a trip to Thailand, causing severe fever, cholangitis and pancreatitis.[ncbi.nlm.nih.gov] Common initial symptoms include: Fatigue Itching of the skin Jaundice Diarrhea Weight loss In more advanced disease, if the bile ducts become infected, patients may have fever[columbiasurgery.org]

  • Hepatitis B

    Mycobacterium tuberculosis infection in a middle-aged Asian woman who initially presented with severe dyspnea on exertion and recurrent syncope, occasional burning chest pains, and fatigue[ncbi.nlm.nih.gov] Hepatitis B Electron micrograph of hepatitis B virus Specialty Infectious disease , gastroenterology Symptoms None, yellowish skin , tiredness , dark urine, abdominal pain[en.wikipedia.org] A 35-year-old man presented to us with fever and loss of consciousness. Four years ago, he was IDU and underwent cardiac surgery because of endocarditis.[ncbi.nlm.nih.gov] A previously healthy 44-year-old woman presented with 3 days of worsening petechial rash, epistaxis and fatigue.[ncbi.nlm.nih.gov]

  • Viral Hepatitis

    In the icteric phase, the patients develop jaundice, gastrointestinal disturbance, dark urine, gray-colored stools, right upper quadrant pain, and hepatomegaly.[symptoma.com] The most frequently reported symptom was fatigue (73.7%), and the most common complications were cholecystitis (0.4%) and fulminant hepatitis (0.4%).[ncbi.nlm.nih.gov] A typhoid patient presenting with fever and jaundice is reported. Investigations revealed that the patient had both typhoid fever and acute viral hepatitis A.[ncbi.nlm.nih.gov] Symptoms of acute (newly acquired) hepatitis include: fever, fatigue, loss of appetite, nausea, vomiting, abdominal/stomach pain, dark urine, clay-colored feces, joint pain[dph.georgia.gov]

  • Choledocholithiasis

    Dark urine. Symptoms associated with Pancreatitis. Charcot's Triad: [ edit ] Clasically seen in common-bile-duct-stone .[en.wikibooks.org] Still, the most statistically significant and useful predictor found in our study was a ratio of direct bilirubin to total bilirubin greater than 30%.[scielo.org.co] The patient was admitted to the Department of Gastroenterology because of fatigue and nausea, with concomitant elevation of alanine aminotransferase (ALT), 550 U/L, and asparagine[ncbi.nlm.nih.gov] By comparing them, was observed that fever and jaundice were the signs and symptoms with statistical significance.[ncbi.nlm.nih.gov]

  • Malignant Neoplasm of Pancreas

    They include yellowing of the skin and eyes, pain in the abdomen and back, weight loss and fatigue.[icd9data.com] Advanced signs and late symptoms include: Jaundice (yellowing of the skin and whites of the eyes) Light-colored stools Dark urine Pain in the upper or middle abdomen and back[netrf.org] […] faeces) to be pale-coloured, and itchy skin Other possible symptoms of pancreatic cancer include: nausea and vomiting changes in bowel movements (diarrhoea or constipation) fever[nhs.uk] Information and support should be available throughout your treatment to help with: fatigue pain changes in appetite or diet anxiety or depression Want to know more?[nhs.uk]

  • Upper Respiratory Infection

    Patients with glomerulonephritis may have loss of appetite, lethargy, dull back pain, and dark urine. Blood pressure may be elevated, and edema may occur.[emedicine.medscape.com] Other symptoms include: fever fatigue headache pain during swallowing wheezing Most people with URIs know what they have.[healthline.com] […] transplant complicated by recurrence of focal segmental glomerulosclerosis and post-transplant lymphoproliferative disorder, presented nearly 2 years after transplantation with fever[ncbi.nlm.nih.gov] Fatigue, may persist Sore throat Sometimes a sore throat Normal energy level Exhaustion Children suffer more colds each year than adults, due to their immature immune systems[chop.edu]

    Missing: Direct Bilirubin Increased
  • Hepatitis E

    The clinical symptoms were subtle with fatigue and vague right upper quadrant tenderness.[ncbi.nlm.nih.gov] Typical signs and symptoms of hepatitis include jaundice (yellow discoloration of the skin and sclera of the eyes, dark urine and pale stools), anorexia (loss of appetite)[hepfi.org] The prevalence rates of prodromal fever, fatigue, loss of appetite, and jaundice were 25.6%, 85.6%, 83.8%, and 92.8%, respectively.[ncbi.nlm.nih.gov] CASE REPORT A 59-year-old male residing in the United States for seven months with a history of malaria treated one year ago presented with fatigue and cholestatic jaundice[ncbi.nlm.nih.gov]

  • Yellow Fever

    Symptoms of weakness and fatigue may last several months in people who recover.[ok.gov] Call your doctor right away if you have signs of liver problems like dark urine, not hungry, stomach pain, light-colored stools, or yellow skin or eyes.[drugs.com] Yellow fever is caused by an enveloped RNA virus called yellow fever virus.[symptoma.com] In this phase people are likely to develop jaundice (yellowing of the skin and eyes, hence the name ‘yellow fever’), dark urine and abdominal pain with vomiting.[who.int]

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