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2,466 Possible Causes for Dark Urine, Enlargement of the Spleen, Fatigue, Fever

  • Primary Biliary Cirrhosis

    Complications from Primary Biliary Cirrhosis can include hypersplenism (enlargement of the spleen), hepatic encephalopathy (confusion or coma resulting from liver failure)[disability-benefits-help.org] This Review article discusses the natural history and the measurement of fatigue in patients with PBC.[ncbi.nlm.nih.gov] We report the case of a 52-year old woman who initially presented to the gastroenterology department for extreme fatigue, pale stools, dark urine and pruritus.[ncbi.nlm.nih.gov] In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena.[ncbi.nlm.nih.gov]

  • Primary Sclerosing Cholangitis

    These include: an enlarged liver or spleen, anaemia , cirrhosis , female sex and older age. Increasing bilirubin also correlates with disease progression.[myvmc.com] Moreover, they experienced less itch (p 0.03) and less Fatigue (p 0.03) and had better Cognitive Abilities (p 0.04) as assessed by the PBC-40 and PBC-27 questionnaires.[ncbi.nlm.nih.gov] Additional symptoms include a general feeling of ill health (malaise); abdominal pain, especially the upper right portion of the abdomen; nausea; dark urine; light-colored[rarediseases.org] The pathogen was supposedly acquired during a trip to Thailand, causing severe fever, cholangitis and pancreatitis.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    .  Red cell removal leads to jaundiceRed cell removal leads to jaundice  Spleen is enlarged (extravascular haemolysis).Spleen is enlarged (extravascular haemolysis).  Intravascular[slideshare.net] Subsequently, he was admitted to our hospital owing to fatigue, a high fever, and jaundice.[ncbi.nlm.nih.gov] A 41-year-old woman with Crohn's disease presented to our emergency room (ER) with dark urine, dizziness, and shortness of breath.[ncbi.nlm.nih.gov] A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov]

  • Malignant Neoplasm of Pancreas

    […] in enlargement of the spleen (splenomegaly).[merckmanuals.com] They include yellowing of the skin and eyes, pain in the abdomen and back, weight loss and fatigue.[icd9data.com] […] either diarrhoea or severe constipation jaundice (yellowish skin and eyes, and dark urine).[cancer.org.au] […] mural nodule Pancreatic Pseudocysts Acute pancreatitis is a clinical syndrome characterized by abdominal and back pain that may be associated with nausea, vomiting, and fever[columbiasurgery.org]

  • Hepatitis B

    Some people have these symptoms: Yellow skin or eyes No appetite (they don't want to eat) Feeling extremely tired Brown or dark urine (pee) Light or gray stools Pain in the[teensource.org] […] liver and spleen.[symptoma.com] Mycobacterium tuberculosis infection in a middle-aged Asian woman who initially presented with severe dyspnea on exertion and recurrent syncope, occasional burning chest pains, and fatigue[ncbi.nlm.nih.gov] A 35-year-old man presented to us with fever and loss of consciousness. Four years ago, he was IDU and underwent cardiac surgery because of endocarditis.[ncbi.nlm.nih.gov]

  • Malaria

    […] liver or enlarged spleen.[nlm.nih.gov] You then develop a high temperature, accompanied by severe sweating and fatigue. These symptoms usually last between 6 and 12 hours.[nhs.uk] Nausea/vomiting, poor appetite, chills, bitter taste in the mouth and dark urine were symptoms that were significantly associated with malaria among the adult clients (P CONCLUSION[ncbi.nlm.nih.gov] Some researchers have suggested that fever reduction may prolong malaria illness.[ncbi.nlm.nih.gov]

  • Acute Hepatic Porphyria

    […] of the spleen.[medical-dictionary.thefreedictionary.com] RESULTS: All patients identified prodromal symptoms that began days prior to acute severe pain; the most common included confusion ("brain fog"), irritability, and fatigue[ncbi.nlm.nih.gov] Muscle weakness, tremor, diaphoresis, dysuria, dark urine, bladder distension and severe neuropathy may be encountered as well, and a missed diagnosis may lead to severe and[symptoma.com] Because the pain is neuropathic, it often is not accompanied by fever or leukocytosis.[hematologyandoncology.net]

  • Babesiosis

    After treatment with a chimeric anti-CD20 antibody preparation (Rituximab), the patient was hospitalised because of anaemia and dark urine from haemoglobinuria.[ncbi.nlm.nih.gov] Some patients will develop enlarged livers or spleens. The usual disease course lasts weeks to several months, but some patients take even longer to fully recover.[columbia-lyme.org] Abstract An 85-year-old man, actively infected with Babesia microti and Ehrlichia chaffeensis, presented with fatigue and thrombocytopenia.[ncbi.nlm.nih.gov] Fevers of unknown origin (FUOs) are defined as prolonged fevers of 101 degrees F or greater lasting 3 or more weeks that remain undiagnosed after comprehensive inpatient/outpatient[ncbi.nlm.nih.gov]

  • Favism

    The abdomen was distended by an enlarged liver and spleen. Neurologic status and findings of the remainder of the examination were normal.[g6pd.org] During a hemolytic crisis when a person's red cells rupture, the sufferer can have symptoms such as jaundice (yellow eyes and skin), paleness, weakness, fatigue, shortness[lydiakang.blogspot.com] Early warning signs include jaundice , dark urine , and a general sense of feeling run down and tired all the time.[wisegeekhealth.com] During a routine screening for G6PD deficiency in the Province of Matera (Southern Italy), an eleven-year-old boy was brought to our attention who had fever obviously caused[ncbi.nlm.nih.gov]

  • Indian Childhood Cirrhosis

    "The child had severe difficulty in breathing and had jaundice with enlargement of liver and spleen besides signs of liver and respiratory failure.[dailymail.co.uk] Affected individuals can experience fatigue, weakness, loss of appetite, weight loss, nausea, swelling (edema), enlarged blood vessels, and yellowing of the skin and whites[icdlist.com] The same bile pigment, bilirubin, which is responsible for the yellow skin tones of jaundice can turn urine dark.[chp.edu] Disease onset may also be sudden, with fever, clay-like stools, jaundice or coma. Cholestasis is generally a late trait of this illness.[symptoma.com]

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