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294 Possible Causes for Dark Urine, Enlargement of the Spleen, Pruritus

  • Primary Biliary Cirrhosis

    Complications from Primary Biliary Cirrhosis can include hypersplenism (enlargement of the spleen), hepatic encephalopathy (confusion or coma resulting from liver failure)[disability-benefits-help.org] We report the case of a 52-year old woman who initially presented to the gastroenterology department for extreme fatigue, pale stools, dark urine and pruritus.[ncbi.nlm.nih.gov] Intense pruritus can be itself an indication to liver transplantation, in extreme cases leading to suicide.[ncbi.nlm.nih.gov]

  • Secondary Biliary Cirrhosis

    It is marked by jaundice, abdominal pain, steatorrhea, and enlargement of the liver and spleen. congestive cirrhosis cirrhosis resulting from increased hepatic venous pressure[medical-dictionary.thefreedictionary.com] With an increase in the appearance of jaundice is observed dark urine and feces discolored.[medicalformat.com] SECONDARY BILIARY CI RR H OS I S Symptoms Clinical features · Jaundice · Pruritus · Biliary colics.[medicscientist.com]

  • Primary Sclerosing Cholangitis

    These include: an enlarged liver or spleen, anaemia , cirrhosis , female sex and older age. Increasing bilirubin also correlates with disease progression.[myvmc.com] Dark urine, as a result of excretion of bile by-products into urine Anorexia, fatigue, malaise (general discomfort or unease), and abdominal pain Nutritional deficiencies,[dovemed.com] Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of bile ducts..Patients with PSC usually presents with fatigue, jaundice and pruritus.[ncbi.nlm.nih.gov]

  • Fascioliasis

    * Diarrhea * Diarrhea * Eggs in stool * Enlarged liver * Enlarged spleen * Eosinophilia * Epigastric pain * Facial swelling * Fever * Fever * Indigestion * Itching * Jaundice[checkorphan.org] The chronic stage is less disturbing, when the patient experiences obstructive jaundice, biliary colic, fat food intolerance, change in bowel habits, pruritus and intermittent[symptoma.com] During this acute phase, the patient complains of headache, anorexia, nausea and vomiting, pruritus, right hypochondrial pain, and high fever with tender hepatomegaly, urticaria[saudijgastro.com]

  • Biliary Atresia

    These may include: jaundice (yellowing of the eyes and skin) dark urine light-colored stools Signs that may appear later include: distended (swollen) abdomen weight loss These[childrenshospital.org] Other symptoms include: Dark yellow or brown urine Gray or white stools Swollen belly Enlarged liver or spleen Kasai procedure The most common treatment for babies with biliary[share.upmc.com] Generalized pruritus secondary to cholestasis is a difficult dermatologic condition to treat.[ncbi.nlm.nih.gov]

  • Progressive Familial Intrahepatic Cholestasis

    […] liver and spleen (hepatosplenomegaly).[ghr.nlm.nih.gov] Clinical description Clinical signs of cholestasis (discolored stools, dark urine) appear within the first year of life in about one third of patients, or later with recurrent[orpha.net] Biliary diversion offers a potential option for intractable pruritus in children with chronic cholestatic disorders.[ncbi.nlm.nih.gov]

  • Hepatosplenomegaly

    A 42-year-old white man had headache, fever, chills, abdominal pain, nausea and vomiting, night sweats, and dark urine for 3 days before admission; he had history of a tick[ncbi.nlm.nih.gov] Hepatomegaly is the medical term used to describe enlargement of spleen and liver.[primehealthchannel.com] Amyloidosis may be associated not only with Hepatolienal syndrome, but also, more rarely, with the advent of cholestatic jaundice and pruritus,.[authorstream.com]

  • Cholangitis

    Signs and symptoms that may appear as the disease progresses include: Pain in the upper right part of the abdomen Fever Chills Night sweats Enlarged liver Enlarged spleen[mayoclinic.org] Dark urine and clay-colored stools. Nausea and vomiting. Yellowing of the skin (jaundice), which may come and go. Quick diagnosis and treatment are very important.[nlm.nih.gov] Pruritus was the most common adverse event; 15% (OCA 10 mg) and 38% (OCA 50 mg) discontinued due to pruritus.[ncbi.nlm.nih.gov]

  • Ascending Cholangitis

    Signs and symptoms that may appear as the disease progresses include: Pain in the upper right part of the abdomen Fever Chills Night sweats Enlarged liver Enlarged spleen[mayoclinic.org] Other symptoms include fever, chills, clay-colored stools, vomiting and nausea, dark urine, and skin yellowing (jaundice).[diethealthclub.com] The patient may also report acholic (putty-coloured) stools and pruritus.[patient.info]

  • Hyperthyroidism

    You should stop either methimazole or PTU and call your doctor if you develop yellow eyes, dark urine, severe fatigue, or abdominal pain.[thyroid.org] Symptoms may include: Low birth weight Small or abnormally shaped head Poor weight gain despite adequate caloric intake Enlarged liver and spleen Goiter Fast heartbeat (which[stanfordchildrens.org] In conclusion, the diagnosis of hyperthyroidism may be delayed in patients in whom the primary manifestations were pruritus and jaundice.[ncbi.nlm.nih.gov]

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