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730 Possible Causes for Dark Urine, Hemolysis, Seizure

  • Skin Infection

    Moreover, ZnO-NPs disrupted biofilm formation and inhibited hemolysis by hemolysin toxin producing S. aureus.[ncbi.nlm.nih.gov] urine Azotemia Hypertension, congestive failure, encephalopathy Low serum complement (acute) Diuresis, weight loss, clinical recovery Elevated streptococcal antibody titer[atsu.edu] The infant recovered, with no seizures by the 16th day from admission, and was off the ventilator by the 18th day.[ncbi.nlm.nih.gov]

  • Atypical Hemolytic Uremic Syndrome

    Mechanical hemolysis is a frequent but usually harmless complication of aortic valve replacement. The most common reason is valvular leakage.[ncbi.nlm.nih.gov] The patient also reported noticing dark urine for several days although denied any frank blood and also denied any diarrhea.[pubs.sciepub.com] The second patient developed cerebral TMA (seizures, vision loss, and nystagmus) 6 days after initial presentation and remained unresponsive to PE/PI.[ncbi.nlm.nih.gov]

  • Disseminated Intravascular Coagulation

    A basic hemolysis workup includes: Hemoglobin and hematocrit ( ). Reticulocyte count ( ).[medicalmediareview.com] Treatment of seizures Treatment of seizures depends on the underlying disorder causing the DIC.[epilepsy.com] , including transfusion reaction, drug induced hemolysis, and Paroxysmal nocturnal hemoglobinuria Vascular malformation and aneurysms Massive tissue injury (includes trauma[clevelandclinicmeded.com]

  • Liver Failure

    Hepatic infarction is an extremely rare and fatal complication associated with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome.[ncbi.nlm.nih.gov] You urinate less than usual, have dark urine, or stop urinating. You vomit blood. You have blood in your bowel movements. You have severe abdominal pain.[drugs.com] A case of a 4-month-old infant with hypertransaminasemia, severe coagulopathy, non ketotic hypoglycemia, moderated metabolic acidosis and neurologic symptoms such as seizures[ncbi.nlm.nih.gov]

  • Phenothiazine

    […] concentration of PtzNH and PozNH accelerated hemolysis.[ncbi.nlm.nih.gov] However, if your urine does become dark, discuss it with your doctor. Some side effects may occur that usually do not need medical attention.[mayoclinic.org] Trifluoperazine may increase the risk of seizures and should be used with caution in people with a history of seizures.[thebody.com]

  • Chlorpromazine

    So far, drugs have commonly been loaded into freshly isolated RBCs using rather disruptive methods based on hypotonic shock, and assessment of damage was restricted to hemolysis[ncbi.nlm.nih.gov] Babies born to mothers who have used this medication during pregnancy may rarely have liver problems with symptoms including yellowing of the eyes/skin or dark urine.[medicinenet.com] […] developmental disability was prescribed chlorpromazine for the target behaviors of aggression and self-injurious behavior (SIB), and she was prescribed phenobarbital for seizures[ncbi.nlm.nih.gov]

  • Wilson Disease

    In pregnant patients with unrecognized WD, liver failure with hemolysis may be interpreted as the low platelet count (HELLP) syndrome.[ncbi.nlm.nih.gov] Blood 2012 120:3171; doi: A 37-year-old woman with no previous medical problems noted malaise, jaundice, and dark urine that rapidly progressed to severe liver failure.[bloodjournal.org] His WD was in a state of remission when he developed the seizure disorder. On endoscopic cyst fenestration, he was relieved of the seizure.[ncbi.nlm.nih.gov]

  • Trifluoperazine

    Injurious effect of DBC to erythrocytes was potentiated by UCB as manifested by a marked increase in hemolysis (171%, p 0.05), and in elution of membrane cholesterol (73%,[ncbi.nlm.nih.gov] urine, signs of kidney problems (such as change in the amount of urine).[webmd.com] Stop taking and see physician NOW: Seizures or skin rash.[psyweb.com]

  • Phenobarbital

    Stability Requirements Temperature Period Room temperature 14 days Refrigerated 14 days Frozen 14 days Freeze/thaw cycles Stable x3 Causes for Rejection Gel-barrier tube; hemolysis[labcorp.com] If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools[chealth.canoe.com] […] on automated seizure detection rates.[ncbi.nlm.nih.gov]

  • Ranitidine

    Clinical evaluation suggested drug-induced Coombs' positive reticulocytopenic hemolysis.[ncbi.nlm.nih.gov] urine and icteric scleras developed.[ncbi.nlm.nih.gov] Theophylline-induced seizures may occur when theophylline serum levels are slightly above the therapeutic range, as in our case report.[ncbi.nlm.nih.gov]

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