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20 Possible Causes for Dark Urine, Intermittent Jaundice, Uric Acid Increased

  • Hereditary Spherocytosis

    Hemolytic crisis results from rapid red cell destruction leading to jaundice, passage of dark urine and anemia. Blood transfusion is the immediate remedial measure.[symptoma.com] Abstract Hereditary spherocytosis is an autosomal dominant congenital hemolytic anemia due to defect in RBC membrane protein that commonly presents with intermittent jaundice[ncbi.nlm.nih.gov] urine A feeling of abdominal fullness related to an enlarged spleen How Is AIHA Diagnosed?[webmd.com]

  • Hepatorenal Syndrome

    Wui-Chiang Lee, Han-Chieh Lin, Ming-Chih Hou, Hsiao-Yi Lin, Fa-Yauh Lee, Sun-Sang Wang, Full-Young Chang and Shou-Dong Lee , Serum Uric Acid Levels in Patients With Cirrhosis[doi.org] Common symptoms of HRS include: confusion delirium nausea vomiting dementia weight gain jaundice (yellowing of your skin and eyes) decreased urine output dark-colored urine[healthline.com] Severe circulatory dysfunction (mean arterial pressure usually is 70 mm Hg) and very low systemic vascular resistance. • Severe liver disease, with jaundice, coagulopathy,[scielo.mec.pt]

  • Primary Biliary Cirrhosis

    We report the case of a 52-year old woman who initially presented to the gastroenterology department for extreme fatigue, pale stools, dark urine and pruritus.[ncbi.nlm.nih.gov] Twenty four hour urine demonstrated a low renal fractional tubular reabsorption of phosphate, increased fractional excretion of uric acid and generalized aminoaciduria.[ncbi.nlm.nih.gov] Reddy AN, Grosberg SJ, Wapnick S: Intermittent cholestatic jaundice and nonmetastatic prostatic carcinoma. Arch Intern Med 1977;137:1616–1618.[clevelandclinicmeded.com]

  • Congenital Liver Cirrhosis

    acid level elevated Maternal mortality, 1%; prematurity and fetal death, 5%-30% Beta blocker, methyldopa, magnesium sulfate; early delivery HELLP syndrome Beyond 22 wk and[clevelandclinicmeded.com] Each child’s symptoms may vary, but may include: Yellowing of the skin and eyes (jaundice) Dark-colored urine Pale, white, or gray-colored stools Belly mass Belly pain Not[hopkinsmedicine.org] He had intermittent high grade fever with dry cough and respiratory distress for 4 days duration.[indianpediatrics.net]

  • Glucose-6-Phosphate Dehydrogenase Deficiency

    An acid urine pH favors production of poorly soluble uric acid over the more soluble urate, increasing the risk for precipitation of intratubular uric acid crystals.[cjasn.asnjournals.org] His major complaint was preceded, in sequence, by a temperature of 102 F (38.9 C), dark urine,[jamanetwork.com] To determine whether you have an inherited G6PD deficiency When a child experienced persistent jaundice as a newborn for unknown reasons; when you have had one or more intermittent[labtestsonline.org]

  • Renal Impairment

    […] in uric acid excretion, serum creatinine, or BUN.[hyper.ahajournals.org] (foamy; dark orange, brown, tea-colored or red if it contains blood; and urinating more or less than normal) Kidney pain felt in their back Sleep problems due to muscle cramps[davita.com] Abstract Benign recurrent intrahepatic cholestasis (BRIC) is a rare autosomal recessive condition characterized by intermittent episodes of pruritus and jaundice that may[ncbi.nlm.nih.gov]

  • Hypercholesterolemia

    urine, or yellowing of the skin or sclera).[circ.ahajournals.org] We report the case of a male infant who had developed failure to thrive, jaundice, intermittent pruritus, and multiple diffuse symmetrical skin xanthomas at 1 year of age.[ncbi.nlm.nih.gov] Gout or increased uric acid.[circ.ahajournals.org]

  • Refractory Megaloblastic Anemia

    Oxygen: pure O2 atmosphere - astronauts Insect venoms: Bee/wasp Spider - brown recluse spiders Most common cause of hemolytic anemia in the world Hemolysis can be severe, urine[brainscape.com] […] degree of in effective erythropoiesis · Haptoglobins, Uric acid and alkaline phosphatase levels – Decreased. · Serum methylmalonate and homocystein levels - Vitamin B-12[sites.google.com] He has a fever and you note jaundice. You order an ultrasound of his abdomen and find multiple gallstones. Lab results: Hct .36 L/L; Hgb 120 g/L. PBS at right.[med-ed.virginia.edu]

  • Hemolytic Anemia due to a Disorder of Glycolytic Enzymes

    […] extravascular hemolysis Can occur in 10% patients with aplastic anemia Clinical symptoms Pallor, excessive fatigue ;, weakness Intermittent jaundice and episodes of red/ dark[amboss.com] However, inosine, which is a naturally occurring substance, increases plasma uric acid levels ( 38 ).[nature.com] If the hemolysis is severe enough, Hb spills over into the urine, resulting in hematuria and dark-colored urine.[doctorlib.info]

  • Hexokinase Deficiency

    Uric Acid), and the patient presents Hyperuricemia.[biochemistryquestions.wordpress.com] urine A feeling of abdominal fullness related to an enlarged spleen How Is AIHA Diagnosed?[webmd.com] Intermittent jaundice and premature pigment gallstones are common. Splenomegaly is characteristic (palpable in 75% to 80% of cases).[web.archive.org]

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