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1,215 Possible Causes for Dark Urine, Iron Deficiency Anemia, Jaundice, Pallor

  • Paroxysmal Nocturnal Hemoglobinuria

    Although the severe obstructive jaundice requiring endoscopic therapy following cholecystectomy was complicated, critical intravascular hemolysis and thrombosis were not observed[ncbi.nlm.nih.gov] […] disorder with insidious onset (usually in the third or fourth decade) and chronic course, characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor[medical-dictionary.thefreedictionary.com] Two years after disease onset, while pancytopenia remained stable, occurrence of morning dark urine led to found a paroxysmal nocturnal hemoglobinuria clone.[ncbi.nlm.nih.gov] Iron staining of the bone marrow demonstrated the absence of stainable iron and sideroblasts. The patient was diagnosed with iron deficiency anemia.[ncbi.nlm.nih.gov]

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net] Clinical description Onset is during infancy with severe anemia, failure to thrive and progressive pallor.[orpha.net] […] may include brittle bones and enlarged spleen Severe thalassemia produces symptoms in the first two years of life, including: pale and listless appearance poor appetite dark[childrensmn.org] CRP C-reactive protein; Hb hemoglobin; IDA iron-deficient anemia; ICP inductively coupled plasma; IE ineffective erythropoiesis; SCD sickle cell disease; sTf transferrin saturation[ncbi.nlm.nih.gov]

  • Achlorhydria

    Clinically, the patient suffered from unremitting watery diarrhea, hypokalemia and achlorhydria with marked anemia and jaundice.[ncbi.nlm.nih.gov] Symptoms Symptoms of pernicious anemia include fatigue , weakness, waxy pallor, shortness of breath, rapid heartbeat, unsteady gait, smooth tongue , gastrointestinal disturbances[britannica.com] List of side effects Abdominal or stomach pain chills clay-colored stools cough dark urine diarrhea difficulty with swallowing dizziness fast heartbeat fever general feeling[rawpaleodietforum.com] KEYWORDS: achlorhydria; chronic atrophic gastritis; iron deficiency anemia; iron malabsorption; pernicious anemia[ncbi.nlm.nih.gov]

  • Acute Glomerulonephritis

    An eight-year-old boy presenting with features of acute glomerulonephritis (AGN), developed jaundice. He was positive for hepatitis A immunoglobulin M.[ncbi.nlm.nih.gov] An examination revealed hypertension ( 95th percentile), pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] Symptoms PSGN Onset of symptoms occurs 1 to 6 weeks after infection; symptoms include hypertension, headache, edema, oliguria, dark urine, reduced urine output, flank pain[medi-info.com] […] much lower than that in cases of iron deficiency anemia, and 3) hemodilution.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] A 41-year-old woman with Crohn's disease presented to our emergency room (ER) with dark urine, dizziness, and shortness of breath.[ncbi.nlm.nih.gov] A 48 year old lady presented with jaundice and exertional breathlesness.[ncbi.nlm.nih.gov]

  • Nephrotic Syndrome

    Acute liver failure with cholestasis and jaundice is a rare complication, with a prevalence of approximately 5%, and is usually associated with a worse prognosis.[ncbi.nlm.nih.gov] […] colored urine Less or no urine Call 911 if your child has: Severe weakness, dizziness, headache, fainting, sleepiness, or confusion Chest pain or shortness of breath Key[urmc.rochester.edu] Although kidney biopsy could not be performed due to a lack of facilities in the country, we made a diagnosis of idiopathic nephrotic syndrome (NS) with iron deficiency anemia[ncbi.nlm.nih.gov] Untreated infants develop symptoms such as rhinorrhea, anemia, jaundice, cutaneous lesions, hepatosplenomegaly, and pseudoparalysis within weeks or months.[ncbi.nlm.nih.gov]

  • Glucose-6-Phosphate Dehydrogenase Deficiency

    G6PD deficiency is found to one important cause of neonatal jaundice developing on day 2 onwards.[ncbi.nlm.nih.gov] His major complaint was preceded, in sequence, by a temperature of 102 F (38.9 C), dark urine,[jamanetwork.com] G6PD deficiency anemia presented mainly with pallor, dark red urine and jaundice after exposure to certain diets, drugs and diseases and therefore patients with G6PD deficiency[ncbi.nlm.nih.gov] Anemia was observed in 20 school children, of whom 3 had iron deficiency anemia.[ncbi.nlm.nih.gov]

  • Hepatosplenomegaly

    A 30-year-old pregnant woman presented at 16 weeks' gestation with epistaxis, jaundice, diffuse abdominal pain and distension, massive hepatosplenomegaly and peripheral oedema[ncbi.nlm.nih.gov] Physical examination revealed an emaciated patient with fever (39 degrees C), pallor, and hepatosplenomegaly (spleen 9 cm and liver 5 cm palpable below the costal margin).[ncbi.nlm.nih.gov] A 42-year-old white man had headache, fever, chills, abdominal pain, nausea and vomiting, night sweats, and dark urine for 3 days before admission; he had history of a tick[ncbi.nlm.nih.gov] African settings, iron deficiency anemia is very common, there is a lack of reported cases of patients presenting with the triad of iron deficiency anemia, hepatosplenomegaly[njcponline.com]

  • Cold Agglutinin Disease

    A 66-year-old man with jaundice and a high titered cold agglutinin was found to have empyema of the gallbladder, a complication of cystic duct cholelithiasis, confirmed at[ncbi.nlm.nih.gov] A 4-year-old girl presented with severe pallor and intermittent passage of cola-coloured urine. Routine investigations were suggestive of auto-immune haemolytic anaemia.[ncbi.nlm.nih.gov] Symptoms during hemolytic crises may include severe pain in the back and legs, headache, vomiting, diarrhea, dark urine, and hepatosplenomegaly.[askhematologist.com] TABLE 5-2 • Differential Diagnosis of Microcytic, Hypochromic Anemia Disorders of iron metabolism Iron deficiency Anemia of chronic disease... ‎ Seite 67 - SJ, et al.[books.google.com]

  • Hemolytic Transfusion Reaction

    Delayed hemolytic transfusion reactions (DHTRs) usually occur between 3 and 14 days posttransfusion as a result of a secondary immune response, with a drop in Hb level, fever, jaundice[ncbi.nlm.nih.gov] Patients may experience hemolytic transfusion reactions that are delayed by from a few days to two weeks and manifest as acute hemolysis (hemoglobinuria, jaundice, and pallor[ncbi.nlm.nih.gov] A 5-year-old male with sickle cell disease presented with pain, dark urine, and fatigue 10 days after a red blood cell (RBC) transfusion.[ncbi.nlm.nih.gov] The case of a 74-year-old woman with a history of chronic iron deficiency anemia requiring transfusion is reported.[ncbi.nlm.nih.gov]

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