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12 Possible Causes for Dark Urine, Progressive or Intermittent Jaundice

  • Obstructive Jaundice

    (ie, progressive, intermittent, fluctuating) The presence of systemic symptoms (eg, fever, anorexia, weight loss) Symptoms of gastric stasis (eg, early satiety, vomiting,[emedicine.medscape.com] Symptoms of obstructive jaundice include the typical yellowing of jaundice as well as dark urine, pale feces, and itching . Also known as post-hepatic jaundice.[medicinenet.com] Symptoms & Effects of obstructive jaundice may include: Dark Urine Pale Faeces Itching Compare obstructive jaundice with hepatocellular jaundice and haemolytic jaundice.[ivyroses.com]

  • Intrahepatic Cholestasis

    A 63-year-old man had a week-long history of intermittent high fever and rapidly progressive jaundice with atypical erythema.[ncbi.nlm.nih.gov] Associated manifestations include fatigue, loss of appetite, dark urine and pale stools. Hepatomegaly is also a common finding.[orpha.net] Less common symptoms include dark urine, pale stools, pain under your ribs or shoulder blade, and some women get jaundiced.[community.babycenter.com]

  • Nonimmune Hemolysis

    Warm autoimmune hemolytic anemia can present as short episodes of anemia, jaundice or may progress to an intermittent chronic pattern. Spleen may become enlarged.[ispub.com] The macrophages then proceed in destroying the “tagged” RBCs producing the typical hemolytic by-products which cause some of the clinically relevant signs such as dark urine[pedclerk.bsd.uchicago.edu] Symptoms may include any of the following: Dark urine Fatigue Pale skin color Rapid heart rate Shortness of breath Yellow skin and whites of the eyes ( jaundice ) Stopping[medlineplus.gov]

  • Acquired Hemolytic Anemia

    Warm autoimmune hemolytic anemia can present as short episodes of anemia, jaundice or may progress to an intermittent chronic pattern. Spleen may become enlarged.[ispub.com] urine A feeling of abdominal fullness related to an enlarged spleen How Is AIHA Diagnosed?[webmd.com] The disease is characterized by symptoms due to the anemia including fatigue, exertional dyspnea, and, more rarely, jaundice and dark urine in case of severe hemolysis.[orpha.net]

  • Infectious Mononucleosis Hepatitis

    Clinical jaundice was noted after the second week and lasted till the sixth week.[smj.org.sg] The dark urine is mostly from the liver. But I'm worried about how high her fever is. Be sure to tell the doctor how high the fever got.[medhelp.org] urine Loss of appetite Muscle pain Itching Young children are likely to have very mild cases of hepatitis A, while symptoms in older children and adults are more likely to[familydoctor.org]

  • Alagille Syndrome

    jaundice Progression to cirrhosis is rare Pathophysiology Two distinct genetic mechanisms: Vast majority (ALGS1) are autosomal dominant, due to mutations in Jagged1 gene[pathologyoutlines.com] In children more than 3 months old, symptoms may include: persistent jaundice severe itchiness fatty deposits in the skin (xanthomas) dark urine or grey or white stools stunted[childrenshospital.org] Cholestasis can cause yellowing of the skin and whites of the eyes (jaundice), itching (pruritus) that may be intense, pale-colored stools, dark urine, fatty sores or bumps[rarediseases.org]

  • Abdominal Angina

    Associated Symptoms fever and chills : inflammation or sepsis distension or bloating: intermittent with IBS, progressive with mass or ascites weight loss: malignancy or IBD[sharinginhealth.ca] , scanty urine Irritability Depression Slight thirst Anorexia after serious illness T: Pink or Red tip C: Yellow and greasy P: Slippery and rapid or Wiry and rapid Treatment[americandragon.com] […] change in bowel habits: malignancy rectal bleeding nausea/vomiting : pain reflex, gastroenteritis, bowel obstruction jaundice : liver, biliary tree, gallbladder or hemolysis[sharinginhealth.ca]

  • Congenital Dyserythropoietic Anemia Type 1

    The shared symptoms include variable intensity anemia, intermittent jaundice, hepato-splenomegaly, and progressive iron overload, most manifest in types I and II.[bloodgenetics.com] She did not report any episodes of acute jaundice in the past, or any dark urine (Table 1 ).[cureus.com]

  • Benign Recurrent Intrahepatic Cholestasis

    Cholestasis, benign recurrent intrahepatic, 1 (BRIC1) [MIM:243300]: A disorder characterized by intermittent episodes of cholestasis without progression to liver failure.[genecards.org] Associated manifestations include fatigue, loss of appetite, dark urine and pale stools. Hepatomegaly is also a common finding.[orpha.net] Associated symptoms include anorexia, weight loss, vomiting, fatigue, dark urine and pale stools. Physical examination is usually unremarkable.[ispub.com]

  • Benign Recurrent Intrahepatic Cholestasis Type 1

    Cholestasis, benign recurrent intrahepatic, 1 (BRIC1) [MIM:243300]: A disorder characterized by intermittent episodes of cholestasis without progression to liver failure.[genecards.org] Associated manifestations include fatigue, loss of appetite, dark urine and pale stools. Hepatomegaly is also a common finding.[orpha.net] Associated symptoms include anorexia, weight loss, vomiting, fatigue, dark urine and pale stools. Physical examination is usually unremarkable.[ispub.com]

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