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714 Possible Causes for Dark Urine, Pruritus, Weight Loss

  • Primary Biliary Cirrhosis

    Early symptoms may include: Nausea and belly pain Fatigue and loss of energy Fatty deposits under the skin Fatty stools Itching Poor appetite and weight loss As liver function[nlm.nih.gov] We report the case of a 52-year old woman who initially presented to the gastroenterology department for extreme fatigue, pale stools, dark urine and pruritus.[ncbi.nlm.nih.gov] Intense pruritus can be itself an indication to liver transplantation, in extreme cases leading to suicide.[ncbi.nlm.nih.gov]

  • Malignant Neoplasm of Pancreas

    A number of factors may cause weight loss in people with pancreatic cancer. The cancer itself may cause weight loss.[mayoclinic.org] Advanced signs and late symptoms include: Jaundice (yellowing of the skin and whites of the eyes) Light-colored stools Dark urine Pain in the upper or middle abdomen and back[netrf.org] Assess for the presence of pruritus and dark urine, which is caused by a buildup of bilirubin in the skin and blood, respectively.[medical-dictionary.thefreedictionary.com]

  • Autoimmune Hepatitis

    Abstract A 25-year-old woman presented with jaundice, palpitation, and weight loss of 5 kg during a period of 2 weeks.[ncbi.nlm.nih.gov] urine.[txliver.com] Fatigue Abdominal pain Joint pain Itching (pruritus) Jaundice An enlarged liver Abnormal blood vessels on the skin (spider angiomas) Nausea and vomiting Loss of appetite Skin[columbiasurgery.org]

  • Secondary Biliary Cirrhosis

    The clinical presentation was with fever, weight loss, cholestatic jaundice with hepatosplenomegaly and generalized lymphadenopathy.[ncbi.nlm.nih.gov] With an increase in the appearance of jaundice is observed dark urine and feces discolored.[medicalformat.com] SECONDARY BILIARY CI RR H OS I S Symptoms Clinical features · Jaundice · Pruritus · Biliary colics.[medicscientist.com]

  • Pancreatic Adenocarcinoma

    The second patient is a 72-year-old male who presented with cholestasis and weight loss.[ncbi.nlm.nih.gov] Advanced signs and late symptoms include: Jaundice (yellowing of the skin and whites of the eyes) Light-colored stools Dark urine Pain in the upper or middle abdomen and back[netrf.org] Pruritus may accompany and often precedes clinical obstructive jaundice. Pruritus can often be the patient's most distressing symptom.[emedicine.medscape.com]

  • Intrahepatic Cholangiocarcinoma

    Other common symptoms at presentation include abdominal pain, weight loss, and fever.[ncbi.nlm.nih.gov] A 64-year-old man presented with right upper-quadrant pain, jaundice, and weight loss.[ncbi.nlm.nih.gov] Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.[icd10data.com]

  • Fascioliasis

    Here, we present a 44-year-old female patient who presented to our hospital with complaints of abdominal pain, nausea, vomiting, anorexia and weight loss.[ncbi.nlm.nih.gov] The chronic stage is less disturbing, when the patient experiences obstructive jaundice, biliary colic, fat food intolerance, change in bowel habits, pruritus and intermittent[symptoma.com] loss, radiological evaluation and serological tests should be performed and fascioliasis should be considered in the differential diagnosis.[ncbi.nlm.nih.gov]

  • Hepatitis

    If you have NAFLD and NASH, your doctor may recommend weight loss and diet changes.[niddk.nih.gov] Acute infection may occur with limited or no symptoms, or may include symptoms such as jaundice (yellowing of the skin and eyes), dark urine, extreme fatigue, nausea, vomiting[web.archive.org] The adverse events observed in the control group encompassed pruritus (11 patients), cephalea (four patients), and nausea and epigastric discomfort (one patient).[doi.org]

  • Primary Sclerosing Cholangitis

    Common initial symptoms include: Fatigue Itching of the skin Jaundice Diarrhea Weight loss In more advanced disease, if the bile ducts become infected, patients may have fever[columbiasurgery.org] Additional symptoms include a general feeling of ill health (malaise); abdominal pain, especially the upper right portion of the abdomen; nausea; dark urine; light-colored[rarediseases.org] Abstract Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of bile ducts..Patients with PSC usually presents with fatigue, jaundice and pruritus.[ncbi.nlm.nih.gov]

  • Jaundice

    Weight Loss After Birth and Neonatal Hyperbilirubinemia Table 4.[doi.org] (illness) The patient was displaying all the symptoms of jaundice: yellow eyes and dark urine.[spanishdict.com] Pruritus occurs before the patient becomes overtly jaundiced. The cause is unknown. Ask about: Weight loss - may suggest an underlying malignancy.[patient.info]

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