Create issue ticket

202 Possible Causes for Darkly Pigmented Skin

  • Acute Intermittent Porphyria

    Acute intermittent porphyria (AIP) belongs to a group of hereditary diseases known as porphyrias which are characterized by defective heme metabolism, leading to excessive cellular secretion of porphyrins and their precursors. Patients with AIP will experience abdominal pain, neuropathies and constipation without[…][symptoma.com]

  • Vitamin D Deficiency

    Individuals with more darkly pigmented skin have greater difficulty producing vitamin D because melanin acts as an effective natural sunscreen, requiring longer sun exposure[ncbi.nlm.nih.gov] pigmented skin.[doi.org] […] in the pathogenesis of rickets at this age include exclusive breast-feeding, maternal vitamin D deficiency, living in temperate climates, lack of sunlight exposure, and darkly[doi.org]

  • Pressure Ulcer

    . • GRADE 1: Discolouration of intact skin not affected by light finger pressure (non blanching erythema) This may be difficult to identify in darkly pigmented skin. • GRADE[judy-waterlow.co.uk] Pain and temperature change often precede skin color changes. Discoloration may appear differently in darkly pigmented skin.[npuap.org] Those with a darkly pigmented skin, or skin discoloration, oedematous skin or hard and indurated skin are at risk of pressure sores.[news-medical.net]

  • Acanthosis Nigricans

    Acanthosis nigricans is a skin disorder characterized by velvety, papillomatous, hyperkeratotic, darkly pigmented skin lesions found in body folds such as the axilla and neck[podiatrytoday.com] pigmented skin.[clinicaladvisor.com] Acanthosis nigricans lesions are characterized by symmetrical, darkly pigmented, velvety plaques.[podiatrytoday.com]

  • Rickets

    pigmented skin and those who are kept primarily indoors (eg, children who are institutionalized).[emedicine.com] Anticonvulsant drugs (eg, phenobarbital, phenytoin) accelerate metabolism of calcidiol, which may lead to insufficiency and rickets, particularly in children who have darkly[emedicine.com]

  • Acne Vulgaris

    The risks of corticosteroid injections include hypopigmentation (particularly in darkly pigmented skin), atrophy, telangiectasias and needle tract scarring.[clinicaladvisor.com]

  • Skin Ulcer

    Pain and temperature change often precede skin color changes. Discoloration may appear differently in darkly pigmented skin.[npuap.org] Those with a darkly pigmented skin, or skin discoloration, oedematous skin or hard and indurated skin are at risk of pressure sores.[news-medical.net] Stage I ulcers are difficult to detect in darkly pigmented skin. The use of mirrors or a penlight may be helpful. Determine the condition of the wound or wound bed.[nurseslabs.com]

  • Keloid

    pigmented skin.[ncbi.nlm.nih.gov] Individuals with darkly pigmented skin are 15 times more likely to develop keloids, with those of African, Hispanic, and Asian ethnicity are at greatest risk.[medicinenet.com] It is well recognized that keloids are more prevalent in populations with darkly pigmented skin, such as African Americans, but the basis for the link between skin color and[ncbi.nlm.nih.gov]

  • Meibomian Cyst

    The most common adverse reaction to this treatment is skin depigmentation (particularly in darkly pigmented patients), but using a transconjunctival approach to injection[webeye.ophth.uiowa.edu]

  • Cholestatic Jaundice

    Examination Jaundice is most easily recognised in fair-skinned individuals and difficult to detect in darkly pigmented patients.[patient.info]

Further symptoms