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116 Possible Causes for Decreased Ankle Reflex, Extremity Ataxia, Progressive Polyneuropathy

  • Chronic Alcoholism

    Wernicke-Korsakoff syndrome (ataxia, confusion, ophthalmoplegia), amnesic problems, peripheral neuropathy and dementia.[patient.info] Investigations Alcohol level is useful in acute comatose state: Alcohol level 300 mg/100 ml extreme intoxication (drowsiness and then coma).[patient.info]

  • Diabetic Polyneuropathy

    Ms Q is a 52-year-old woman who has had progressive polyneuropathy in the setting of diabetes for the past 8 years.[ncbi.nlm.nih.gov] Deep tendon reflexes were symmetric and graded 2 in all extremities.[openaccessjournals.com] […] but are less sensitive. 2, 7,9,12 Decreased ankle reflexes are also common, as well as the electrodiagnostic equivalent, H reflexes.[dynamicchiropractic.com]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    Shortly after HSCT the patient developed progressive polyneuropathy of the lower legs and hypoesthesia. Five months later a severe dementia followed.[ncbi.nlm.nih.gov] On admission, the patient exhibited bifacial, extremity weakness, ataxia, impaired sensation, and areflexia. Electrophysiology and nerve biopsy suggested demyelination.[ncbi.nlm.nih.gov] We report a 58-year-old woman with DADS that progressed to a severe case of classic CIDP.[ncbi.nlm.nih.gov]

  • Guillain-Barré Syndrome

    Guillain-Barré syndrome is a rare condition in pregnancy which is characterised by symmetrical progressive ascending polyneuropathy.[ncbi.nlm.nih.gov] , and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk.[icd10data.com] […] correlates with decreased/absent ankle reflex MRI cauda equina gandolinium enhancement in acute cases DIfferential Diagnosis Myasthenia gravis, ALS, infectious myelitis ([step2.medbullets.com]

  • Arsenic-Induced Polyneuropathy

    ., sensory ataxia due to vitamin B 12 deficiency) Deep tendon reflexes References: [10] [11] [12] [9] Subtypes and variants Diabetic polyneuropathy Definition : progressive[amboss.com] […] jerks, tremors, seizures, an impaired ability to coordinate voluntary movements (ataxia), and/or inability to stand or walk.[rarediseases.org] […] neuropathy likely. 4 The isolated presence of neuropathic symptoms or decreased ankle reflexes is less valuable for diagnosis.[aafp.org]

  • Vitamin B12 Deficiency

    peripheral neuropathy, and spinal degeneration.[ncbi.nlm.nih.gov] In later stages, spasticity, extensor plantar responses, greater loss of position and vibratory sensation in the lower extremities, and ataxia emerge.[merckmanuals.com] In mildly affected cases the activity of the knee and ankle jerks may be either increased or diminished but in severely affected patients these reflexes are always decreased[ispub.com]

  • Hypertrophic Interstitial Neuropathy

    356.4 specified type NEC 356.8 in diseases classified elsewhere - see Polyneuropathy, in leg NEC 355.8 lower extremity NEC 355.8 upper extremity NEC 354.9 progressive hypertrophic[healthprovidersdata.com] Other symptoms may include pain in the extremities, curvature of the spine, clawed hands, foot deformities, ataxia, peripheral areflexia, and slow acquisition of motor skills[en.wikipedia.org] […] with marked disturbances of sensation and ataxia of movement and caused by an interstitial hypertrophic neuritis that ascends with consecutive medullary [cord] lesions.[karger.com]

  • Pernicious Anemia

    We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia[ncbi.nlm.nih.gov] In mildly affected cases the activity of the knee and ankle jerks may be either increased or diminished but in severely affected patients these reflexes are always decreased[ispub.com] ), ataxia and positive Babinski reflexes.[doi.org]

  • Familial Progressive Polyneuropathy

    Abstract The purpose of this study was to evaluate the clinical and pathological features in patients with progressive-type familial amyloidotic polyneuropathy (FAP) using[ncbi.nlm.nih.gov] […] with marked disturbances of sensation and ataxia of movement and caused by an interstitial hypertrophic neuritis that ascends with consecutive medullary [cord] lesions.[karger.com] […] neuropathy likely. 4 The isolated presence of neuropathic symptoms or decreased ankle reflexes is less valuable for diagnosis.[aafp.org]

  • Autosomal Recessive Spinocerebellar Ataxia Type 17

    Clinical features Ataxia, chorea, and axonal polyneuropathy Cutaneous photosensitivity and multiple cancers Mental and motor retardation Microcephaly Sensorineural deafness[emedicine.medscape.com] […] the extremities, truncal ataxia, increased reflexes in the lower extremities, and intellectual disability.[malacards.org] Important neurologic signs other than cerebellar ataxia include peripheral neuropathy (decreased or absent tendon reflexes and decreased ankle reflexes); movement disorders[blogs.nejm.org]

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