Entry H00150 Disease Name Danon disease; X-linked vacuolar cardiomyopathy and myopathy Supergrp Lysosomal storage disease [DS: H01425 ] Description Danon disease is an X-linked disorder caused by deficiency of lysosomal-associated membrane protein Lamp2 and resulting in cardiomyopathy, myopathy, and mental[…]
[genome.jp]
These mechanisms are supported by the decreased venous return and post-load and increased contractility.
[scielo.br]
All of them act by controlling the physiopathological mechanisms of the symptoms: decrease in cardiac contractility, decrease in HR and increase in diastolic filling time37
[scielo.br]
The obstruction of the outflow tract is one of these mechanisms, aided by the venous return decrease, increased cardiac contractility and decreased left ventricular post-load21
[scielo.br]
VAR_045919 179 - 179 R -> H (in MYMY5 and MSMDYS; disease phenotype include smooth muscle cells dysfunction in organs throughout the body with decreased contractile function
[rbcc.hegelab.org]
Variant description: In MYMY5 and MSMDYS; disease phenotype include smooth muscle cells dysfunction in organs throughout the body with decreased contractile function in the
[web.expasy.org]
It has been suggested that ACTA2 missense mutations disrupt alpha-actin polymerization and lead to decreased contractility of aortic SMCs, which in turn leads to thoracic
[journals.lww.com]
This can lead to vasodilation, decreased systemic vascular resistance, bradycardia, conduction delay, decreased contractility, hypotension and cardiogenic shock.
[coreem.net]
Cardioselective blockers (e.g., atenolol, bisoprolol ) primarily block β 1 receptors in the heart, causing decreased heart rate and cardiac contractility, slower AVN conduction
[amboss.com]
While hypotension, bradycardia, decreased myocardial contractility and oxygen consumption account for the hemodynamic instability, hypoglycemia secondary to inhibition of
[ncbi.nlm.nih.gov]
It can “stun” the heart, causing decreased contractility and wall movement, especially at the apex, or bottom, of the heart.
[americannursetoday.com]
contractility, right and left ventricular wall thinning, and, eventually, heart failure with neurohormonal activation.
[escardio.org]
[…] myocardial contractility caused by ventricular fibrillation may also be irreversible shock, central nervous system inhibition, ECG may have T wave is low, there U wave, QT
[healthfrom.com]
In adults older than 60 years, 50-100 ml of residual urine may remain after each voiding because of the decreased contractility of the detrusor muscle. [4] In chronic retention
[en.wikipedia.org]
This obstruction is exacerbated by conditions causing a small left ventricular cavity: decreased preload, increased contractility, and tachycardia.
[anesthesiology.pubs.asahq.org]
Volatile anesthetics are ideal in that they decrease contractility (but also decrease afterload and lead to junctional rhythms – consider a TEE probe or PA catheter with pacing
[openanesthesia.org]
Hypotension due to LVOT can be controlled in various ways, such as the use of β-blockers that decrease the excessive contractility of the base of the heart and lower the level
[news-medical.net]
Receptor stimulation results in the triggering of a reflex in the form of heart rate slowing, decrease in contractility, vasodilatation, and, as a result, a fall in blood
[vdoc.pub]
Both nifedipine and the nitroglycerine patch have been shown to significantly decrease systolic blood pressure.
[vdoc.pub]
Additionally, non-dihydropyridine calcium channel blockers may cause OH through negative effects on cardiac contractility and conduction, preventing compensatory increases
[vdoc.pub]
The decreased contractility causes a decrease in stroke volume typical haemodynamic picture: decreased cardiac output and blood pressure high left ventricular filling pressures
[aic.cuhk.edu.hk]
As a result of decreased contractility, the patient develops elevated left and right ventricular (RV) filling pressures and a low cardiac output.
[www1.cgmh.org.tw]
As a result of decreased contractility, the patient develops elevated LV and RV filling pressures and low cardiac output.
[emedicine.com]
contractility, which can precipate or worsen CHF exacerbations.
[errolozdalga.com]
Cardiac function is significantly depressed due to the decreased contractility of the myocytes due to the low T3 hormones that decreases available supply of adenosine triphosphate
[symptoma.com]
Cardiovascular Cardiac contractility is impaired, leading to reduced stroke volume, low cardiac output, bradycardia and sometimes hypotension. [6] Reduced stroke volume in
[emedicine.com]
contractility. [25, 32] This has been documented in the rat model.
[emedicine.medscape.com]
• Gallbladder contractility • Hemoglobin • Uric acid levels • Albumin, total protein, and antithrombin III concentrations • No change: • Liver aminotransferase levels (AST
[slideshare.net]
Gallbladder contractility Hemoglobin level (because of volume expansion) Uric acid level Albumin and total protein levels Antithrombin III and protein S level Systemic vascular
[clevelandclinicmeded.com]
Isolated dilation and subsequent decrease in contractility of right ventricle (RV) is rare.
[amboss.com]
Furthermore, epinephrine can also lead to abnormal myocardial and cellular remodeling, which further result in biventricular dilatation, decreased contractility, and elevation
[intechopen.com]
[…] calcium sensitivity in the myofilaments and consequent decreased contractility. [32], [33] Interestingly, Sun et al. found that DCM iPS-derived cardiomyocytes were more susceptible
[journals.plos.org]
contractility of the smooth muscle cells, and decreases the transit rate of the intestinal content.15 In the aganglionic intestine and in the HD transition zone, there may
[elsevier.es]
[…] development of anti-c-kit antibodies for the histological identification of these cells.14 The absence or reduction in the number of ICC determines slow-wave abnormalities, causes decreased
[elsevier.es]
It decreases blood flow to uterus, fetal oxygenation and intestinal blood flow. It increases uterine contractility 41 Cocaine Microcephaly Prematurity Low birth weight.
[slideplayer.com]
Abstract Alcoholic cardiomyopathy is characterized by cardiomegaly, disruptions of myofibrillary architecture, reduced myocardial contractility, decreased ejection fraction
[ncbi.nlm.nih.gov]
Excessive alcohol ingestion causes myocardial damage including disruptions of the myofibrillar architecture and is associated with reduced myocardial contractility and decreased
[ncbi.nlm.nih.gov]
The loss of contractile efficiency of the heart's output leads to decreased stroke volume. There is a backup of returning blood to the LV and it begins to dilate.
[healthboards.com]
[…] coronary artery curve decrease diagnosis diastolic digitalis diuretics drug dyspnea ectopic effect ejection electrocardiogram fibers fibrillation filling findings first fluid function
[books.google.de]
Thyroid hormone effects on the heart and peripheral vasculature include decreased SVR and increased resting heart rate, left ventricular contractility, and blood volume (Figure
[ecgmojo.com]
[…] systemic vascular resistance and increased resting heart rate, left ventricular contractility, blood volume, and cardiac output.
[ncbi.nlm.nih.gov]
The loss of cardiac inotropy (i.e., decreased contractility) causes a downward shift in the Frank-Starling curve (red curve in figure).
[cvphysiology.com]
Confirmatory tests Transthoracic echocardiography can help identify patients with decreased contractile function.
[cancertherapyadvisor.com]
Cardiomyopathies Dilated cardiomyopathy (DCM) is characterized by dilatation of one or both of the ventricles of the heart, with a general decrease in contractility and consequently
[textbookofcardiology.org]
Rhythm disturbances and decreased myocardial contractility were less frequently observed, along with other cardiac and hemodynamic changes.
[emedicine.medscape.com]
[…] cardiac output due to decreased contractility Arrhythmias Neurological consequences Neuromuscular overexcitability Decreased cerebral blood flow due to cerebral vasoconstriction
[derangedphysiology.com]
[…] myocardial contractility arrhythmias RESP impaired peripheral oxygen unloading (due shift of oxygen dissociation curve to left) – hypoxaemia may occur and oxygen delivery
[litfl.com]
These changes lead to decreased myocardial contractility, arrhythmias, decreased cerebral blood flow, confusion, increased neuromuscular excitability, and impaired peripheral
[ncbi.nlm.nih.gov]
Post resuscitation injury Burn etc Chemical mediators Endotoxin Cytokines TNF IL-1, 6, 10 Epi, NA CAMs NO •Conduction disturbance •Decreased contractility
[slideshare.net]
Echocardiographic signs include abnormal cardiac wall motion, decreased cardiac contractility, valvular dysfunction or rupture, septal defects, intracardiac thrombus, and
[annals.in]
This reduces sympathetic outflow to the heart thereby decreasing cardiac output by decreasing heart rate and contractility.
[cvpharmacology.com]
Cardioselective blockers (e.g., atenolol, bisoprolol ) primarily block β 1 receptors in the heart, causing decreased heart rate and cardiac contractility, slower AVN conduction
[amboss.com]
Activation of gene programs that decrease myocardial contractility.
[thecardiologyadvisor.com]
contractility, which can precipate or worsen CHF exacerbations.
[errolozdalga.com]
CV abnormalities Bradycardia Decreased myocardial contractility Low cardiac output Hypotension Pericardial effusion Hypoventilation Results from: Central depression of ventilatory
[lilywhite.us]
Myxedema Coma - hallmarks are Decreased Mental Status and Hypothermia, in addition to exaggerated symptoms of severe hypothyroidism.
[errolozdalga.com]
Two-dimensional Doppler echocardiogram and right ventriculogram showed marked dilatation and decreased contractility of the right ventricle as well as tricuspid regurgitation
[ncbi.nlm.nih.gov]
LV preload and contractility (Figure 1). 25,27 Compression of the left main coronary artery by a dilated main pulmonary artery, which is occasionally observed in pulmonary
[revespcardiol.org]
[…] afterload may shift the interventricular septum and increase pericardial constraint on the left ventricle; both of these changes may alter left ventricular geometry and decrease
[revespcardiol.org]
In contrast, decreased contractile states account for a smaller percentage of causes of pediatric HF.
[pedsinreview.aappublications.org]
This patient shows augmentation of a previously poorly functioning region on low dose dobutamine (10 |g), but demonstrates ischemia (decreased contractility) at higher doses
[barnardhealth.us]
contractility [31-33].
[oatext.com]
Blockers – these drugs decrease myocardial oxygen demand by reducing blood pressure (i.e. decreasing wall tension), contractility, and heart rate; through venodilatation,
[cancertherapyadvisor.com]
Beta-blocker therapy, which blocks the sympathetic nervous system, will decrease contractility; this, in turn, decreases oxygen demand and relieves symptoms of angina.
[healio.com]
[…] heart rate, contractility, and cardiac output – which reduces cardiac O2 demand Calcium channel blocker (e.g. verapamil, diltiazem) These two agents are preferred due to
[almostadoctor.co.uk]
Malnutrition & Vitamin Deficiency Kwashiorkor or Marasmus or Both Effects of starvation on the heart: Decreased contractile force decreased cardiac output Diminished diastolic
[slideshare.net]
Hypothyroidism Initial Diagnosis: Pericardial effusion or decreased contractile performance Clinical suspicion of hypothyroidism Definite Diagnosis: Clinical findings Biochemical
[slideshare.net]
tachycardia Decreased SVR 52.
[slideshare.net]
[…] obstruction as evidenced by decreased oxygen saturation levels 19. Impaired tissue perfusion related to decreased cardiac contractility and expiratory airflow obstruction
[slideshare.net]
NURSING DIAGNOSIS• Decreased cardiac output related to restricted cardiac muscle contractility as evidenced by echocardiographic finding• Impaired gas exchange related to
[slideshare.net]
Decreased cardiac output related to restricted cardiac muscle contractility as evidenced by echocardiographic finding Impaired gas exchange related to expiratory airflow
[slideshare.net]
Porselvi Abstract Dilated cardiomyopathy (DCM) is an idiopathic condition manifesting decreased contractility of heart, which is irreversible and slowly progressive.
[japer.in]
Isolated dilation and subsequent decrease in contractility of right ventricle (RV) is rare.
[amboss.com]
contractility; Impaired relaxation Other mutations produce: Hypertrophic cardiomyopathy (CMH 12) Dilated cardiomyopathy 1N (CMD 1N) ● Telethonin (TCAP) ; Chromosome 17q12
[neuromuscular.wustl.edu]
Decreased contractility and lacrimal gland hypersecretion both cause dilatation of the ductal wall and subsequent cyst formation [1–3].
[hindawi.com]
Severe hypercapnia may cause decreased myocardial contractility, arrhythmias, and peripheral vasodilatation, particularly when the serum pH decreases to Table 2.
[ime.acponline.org]
