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Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is an aggressive disease in which normal lung parenchyma is replaced by a stiff dysfunctional scar rich in activated fibroblasts and collagen-I. We examined how the mechanochemical pro-fibrotic microenvironment provided by matrix stiffening and TGF-β1 cooperates in the[…][ncbi.nlm.nih.gov]
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Desquamative Interstitial Pneumonia
Lung function showed decreased pulmonary compliance; lung biopsy showed desquamative interstitial pneumonitis.[ncbi.nlm.nih.gov]
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Farmer's Lung
lung compliance.[emedicine.medscape.com]
If the exposure is prolonged and continuous, collagen deposition and destruction of the lung parenchyma occur with resultant decreased lung volumes.[emedicine.medscape.com]
[…] exposure is large, a dramatic increase in inflammation leads to increased vascular permeability, which can alter the alveolar capillary units, thus promoting hypoxemia and decreased[emedicine.medscape.com]
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Restrictive Lung Disease
[…] fibrosis of lung parnechyma decreased lung compliance impaired diffusion of gases dyspnea, first on exertion then later at rest[quizlet.com]
Common causes of decreased lung compliance are pulmonary fibrosis, pneumonia and pulmonary edema.[medicine.mcgill.ca]
[…] characteristics of restrictive lung diseases something is impairing the ability of lungs to expand and inflate causing decreasing lung compliance -secondary to damage to thoracic[quizlet.com]
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Acute Respiratory Distress Syndrome
Hallmarks of ARDS include hypoxemia and decreased lung compliance, increased work of breathing, and impaired gas exchange.[ncbi.nlm.nih.gov]
lung compliance.[hamilton-medical.com]
[…] and decreased lung compliance.[lifeinthefastlane.com]
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Pulmonary Fibrosis
Additionally, the static pressure-volume curve is shifted downward and to the right as a result of decreased lung compliance.[physio-pedia.com]
Fibrosis leads to decreased lung compliance and increased elastic recoil, which increases the overall work of breathing and inefficient exchange of gases.[medical-dictionary.thefreedictionary.com]
The replacement of normal lung with scar tissue causes irreversible decrease in oxygen diffusion capacity, and the resulting stiffness or decreased compliance makes pulmonary[en.wikipedia.org]
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Pulmonary Contusion
This blunt lung injury develops over the course of 24 hours, leading to poor gas exchange, increased pulmonary vascular resistance and decreased lung compliance.[prep4usmle.com]
Large hemorrhages from contusions may lead to ventilation/perfusion mismatch, pulmonary edema, and decreased lung compliance. 6 , 7 Table: Characteristics of Pulmonary Contusion[pulmonarychronicles.com]
Chest Trauma Pulmonary Contusion Pulmonary contusion is an injury to lung parenchyma, leading to oedema and blood collecting in alveolar spaces and loss of normal lung structure[trauma.org]
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Crack Lung
Clinical findings A 6–24-hour latency period is followed by hypoxia, decreased aeration, dyspnoea, severe SOB and “stiff” lungs—i.e., decreased pulmonary compliance.[medical-dictionary.thefreedictionary.com]
. observations Signs and symptoms include dyspnea, tachypnea, adventitious breath sounds, hypoxemia, and decreased lung compliance.[medical-dictionary.thefreedictionary.com]
150,000/year (US), and is characterised by acute pulmonary oedema and respiratory failure, poor oxygenation, increased functional residual capacity and decreased compliance[medical-dictionary.thefreedictionary.com]
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Extrinsic Allergic Alveolitis
A decrease in DLco and in lung compliance in EAA patients was observed but no significant correlation between pulmonary functional tests and serum angiogenic activity measured[ncbi.nlm.nih.gov]
Decreased compliance giving a RESTRICTIVE pattern in pulmonary function tests. (Fev1/FVC ratio 80%).[almostadoctor.co.uk]
End stage is “honeycomb lung”, cystic spaces develop in fibrotic lungs.[almostadoctor.co.uk]
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Diffuse Pulmonary Lymphangiomatosis
Decreased lung compliance increases the work of breathing and energy expenditure.[emedicine.medscape.com]