Decreased Lung Compliance: Causes & Reasons

Possible Causes for Decreased Lung Compliance

Common causes of decreased lung compliance are pulmonary fibrosis, pneumonia and pulmonary edema. [medicine.mcgill.ca]

In a restrictive lung disease, the compliance of the lung is reduced, which increases the stiffness of the lung and limits expansion. [ugr.es]

Respiration Laboratory T heory > Lung Diseases In a restrictive lung disease, the compliance of the lung is reduced, which increases the stiffness of the lung and limits expansion [medicine.mcgill.ca]

Acute Respiratory Distress Syndrome

Hallmarks of ARDS include hypoxemia and decreased lung compliance, increased work of breathing, and impaired gas exchange. [ncbi.nlm.nih.gov]

It is characterized by the acute onset of diffuse, bilateral pulmonary infiltrates secondary to noncardiogenic pulmonary edema, refractory hypoxia, and decreased lung compliance [ncbi.nlm.nih.gov]

Also decrease lung compliance is another feature of ARDS due to decrease area of aeration and fibrosis. [youtube.com]

Pulmonary Contusion

This blunt lung injury develops over the course of 24 hours, leading to poor gas exchange, increased pulmonary vascular resistance and decreased lung compliance. [prep4usmle.com]

Chest Trauma Pulmonary Contusion Pulmonary contusion is an injury to lung parenchyma, leading to oedema and blood collecting in alveolar spaces and loss of normal lung structure [trauma.org]

Large hemorrhages from contusions may lead to ventilation/perfusion mismatch, pulmonary edema, and decreased lung compliance. 6, 7 Table: Characteristics of Pulmonary Contusion [pulmonarychronicles.com]

Ventilation Pneumonitis

Depending on the pattern of ventilation a patient may suffer from restrictive lung disease (impairing lung ventilation) caused by decrease in the lung compliance. [intellectbreathing.com]

Neutrophils damage the vascular endothelium and alveolar epithelium, leading to pulmonary edema, hyaline membrane formation, decreased lung compliance, and difficult air exchange [aafp.org]

PEEP=the higher of PEEPi and PEEPe - dynamic effective compliance reduced by decreases in lung or chest wall compliance or increases in airway resistance while static compliance [aic.cuhk.edu.hk]

Pigeon Breeder's Lung

The functional abnormality is essentially a restrictive ventilatory disturbance with impairment of gas transfer and decrease in lung compliance. [tandfonline.com]

The clinical features, common to these conditions, consist of pulmonary (dyspnoea, cough, thoracic aches, fine crepitations at both lung bases) and systemic (fever, chills [tandfonline.com]

Desquamative Interstitial Pneumonia

Lung function showed decreased pulmonary compliance; lung biopsy showed desquamative interstitial pneumonitis. [ncbi.nlm.nih.gov]

Morbid Obesity

Definition The overall respiratory problem is one of restrictive lung disease. Chest wall and lung compliance are decreased from the heavy layer of fat. [openanesthesia.org]

Also, excessive adipose tissue over the chest decreases the chest wall compliance, and increased abdominal mass forces the diaphragm upwards and reduces lung volumes. [openanesthesia.org]

Because awake MO patients already have severe alterations of their respiratory mechanics (10) (decreased chest wall and lung compliance, decreased functional residual capacity [journals.lww.com]

Pulmonary Fibrosis

Additionally, the static pressure-volume curve is shifted downward and to the right as a result of decreased lung compliance. [physio-pedia.com]

Fibrosis leads to decreased lung compliance and increased elastic recoil, which increases the overall work of breathing and inefficient exchange of gases. [medical-dictionary.thefreedictionary.com]

The replacement of normal lung with scar tissue causes irreversible decrease in oxygen diffusion capacity, and the resulting stiffness or decreased compliance makes pulmonary [en.wikipedia.org]

Farmer's Lung

lung compliance. [emedicine.com]

If the exposure is prolonged and continuous, collagen deposition and destruction of the lung parenchyma occur with resultant decreased lung volumes. [emedicine.com]

[…] exposure is large, a dramatic increase in inflammation leads to increased vascular permeability, which can alter the alveolar capillary units, thus promoting hypoxemia and decreased [emedicine.com]

Pulmonary Scleroderma

[…] disease -> predicts worse prognosis) PFT’s (abnormal in 90% of cases): restriction with decreased lung compliance (not due to chest wall skin changes) DLCO: isolated decrease [mdnxs.com]

Technetium-DTPA Clearance Study: has been used to predict prognosis in some centers (more rapid clearance indicates more disrupted epithelial integrity consistent with interstitial lung [mdnxs.com]

Chronic Interstitial Lung Disease

Characterized by reduced lung volumes/decreased lung compliance. Give some examples of restrictive lung disorders (6). [quizlet.com]

Any organ may be involved with the lungs, lymphatics, skin, liver, eyes most commonly affected in decreasing order. [lumen.luc.edu]

Give some examples of obstructive lung disorders (4). -Asthma -COPD (emphysema/chronic bronchitis) -Bronchiectasis -Cystic Fibrosis Summarize restrictive lung disorders. [quizlet.com]

Chronic Obstructive Pulmonary Disease

The tissue damage in the lungs leads to poor compliance (the elasticity, or ability of the lung tissue to expand). [medicinenet.com]

Emphysema causes a decrease in elastic recoil pressure and an increase in lung compliance. [doi.org]

The decrease in elasticity of the lungs means that oxygen in the air cannot get by obstructions (for example, thick mucus plugs) to reach air spaces (alveoli) where oxygen [medicinenet.com]

Diffuse Pulmonary Lymphangiomatosis

Decreased lung compliance increases the work of breathing and energy expenditure. [emedicine.medscape.com]

Interstitial Lung Disease

Any organ may be involved with the lungs, lymphatics, skin, liver, eyes most commonly affected in decreasing order. [meddean.luc.edu]

[…] manifestations to watch for: - Myocardial involvement (possible conduction disturbances) - Uveitis - Cranial nerve VII involvement - Erythema nodosa PFTs: Decreased volumes, compliance [meddean.luc.edu]

Asbestosis

This fibrosis can lead to Reduced lung volumes, Decreased lung compliance, Impaired gas exchange, Restrictive pattern of impairment, Obstructive features due to small airways [atsdr.cdc.gov]

[…] pulmonary compliance ) Early: decreased DL CO Later: reduced vital capacity and total lung capacity Normal to increased ratio of FEV 1 to FVC Bronchoalveolar lavage Biopsy [amboss.com]

Supradiaphragmatic and pleural reticulonodular opacities / plaques Rounded atelectasis In some cases, pleural effusion HR- CT : Pulmonary function test : Restrictive ventilatory defects (decreased [amboss.com]

Extrinsic Allergic Alveolitis

Decreased compliance giving a RESTRICTIVE pattern in pulmonary function tests. (Fev1/FVC ratio >80%). [almostadoctor.co.uk]

End stage is “honeycomb lung”, cystic spaces develop in fibrotic lungs. [almostadoctor.co.uk]

Pulmonary fibrosis is the end result of many respiratory diseases, it is characterised by: Scar tissue in the lungs. [almostadoctor.co.uk]

Pneumothorax

Gastric inflation can elevate the diaphragm, restrict lung movement, and decrease respiratory system compliance. 14, –, 16 Airway Adjuncts Cricoid Pressure Cricoid pressure [web.archive.org]

Gastric inflation can elevate the diaphragm, restrict lung movement, and decrease respiratory system compliance. 14 – 16 Airway Adjuncts Cricoid Pressure Cricoid pressure [doi.org]

Acute Interstitial Lung Disease

Normal lung parenchyma is interspersed with areas of decreased compliance and extensive parenchymal alterations. [thoracicmedicine.org]

Any organ may be involved with the lungs, lymphatics, skin, liver, eyes most commonly affected in decreasing order. [lumen.luc.edu]

This is unlike ARDS where the pattern of lung injury is more uniform. [thoracicmedicine.org]

Crack Lung

Signs and symptoms include dyspnea, tachypnea, adventitious breath sounds, hypoxemia, and decreased lung compliance. [medical-dictionary.thefreedictionary.com]

Clinical findings A 6–24-hour latency period is followed by hypoxia, decreased aeration, dyspnoea, severe SOB and “stiff” lungs—i.e., decreased pulmonary compliance. [medical-dictionary.thefreedictionary.com]

±150,000/year (US), and is characterised by acute pulmonary oedema and respiratory failure, poor oxygenation, increased functional residual capacity and decreased compliance [medical-dictionary.thefreedictionary.com]

Berylliosis

These decreased values occur as fibrosis stiffens the lungs. [medical-clinic.org]

and compliance. [medical-clinic.org]

Pulmonary function studies demonstrate decreased vital capacity, forced vital capacity, residual volume to total lung capacity ratio, diffusing capacity for carbon monoxide [medical-clinic.org]

Pulmonary Histiocytosis X

[…] of the lung decreases dynamic volumes, while air trapping increases RV leading to globally normal static volumes [ 21 ]. [journals.plos.org]

This functional profile—commonly called “pseudorestriction”—is typically observed in bronchiolar diseases, in which decreased pulmonary compliance due to cellular infiltration [journals.plos.org]

Pneumoconiosis

Excessive ventilation on exercise could be the result of decreased chest wall and/or lung compliance caused by pleural thickening alone or to decreased lung compliance and [atsjournals.org]

Half of subjects with pleural thickening but normal chest films and normal lung function showed excessive ventilation with exercise, which can contribute to dyspnea ( 114 [atsjournals.org]

Obesity

Living Large: Obesity In America In a series, NPR looks at how life is changing in a country where tens of millions of people are obese — in the home, at the grocery store, in the doctor's office, on the factory floor and at the airport. Savannah Davis, 16, of Lufkin, Texas, poses on the Wellspring campus. Travis[…] [npr.org]

Bronchioloalveolar Carcinoma

In 1999, the World Health Organization (WHO) redefined bronchioloalveolar carcinoma (BAC) to include only those lesions with a so-called pure lepidic (classic) growth pattern with no evidence of invasion by a tumor. If stromal, vascular, or pleural invasion are present, the neoplasm is classified as an adenocarcinoma,[…] [e-immunohistochemistry.info]

Idiopathic Pulmonary Fibrosis

Genentech’s Esbriet ( pirfenidone ), approved by the U.S. Food and Drug Administration (FDA) in 2014 to treat idiopathic pulmonary fibrosis (IPF), prolongs survival in patients and is generally safe, concludes a review, “ Role of pirfenidone in the management of pulmonary fibrosis ,” that recently appeared in the[…] [lungdiseasenews.com]

Cryptogenic Organizing Pneumonia

Cryptogenic organizing pneumonia ( COP ), also known as bronchiolitis obliterans organizing pneumonia ( BOOP ), is an inflammation of the bronchioles ( bronchiolitis and surrounding tissue in the lungs). [1] [2] It should not be confused with bronchiolitis obliterans, a form of non-infectious pneumonia. It is often a[…] [en.wikipedia.org]

Interstitial Pulmonary Fibrosis of the Newborn

Children’s interstitial and diffuse lung disease (ChILD) is not one disease or disorder, but a number of them. These diseases cause a thickening of the interstitium (the tissue that extends throughout the lungs) due to scarring, inflammation or fluid buildup. This thickening affects carbon dioxide and oxygen[…] [chop.edu]

Axial Spondyloarthritis

Copy/Paste the key inputs from the product brochure, per guidance from Marketing. The axial spondyloarthritis (AxSpA) market boasts biologics representing two distinct drug classes, the blockbuster tumor necrosis factor-alpha (TNF-α) inhibitors (Amgen’s Enbrel, AbbVie’s Humira, Janssen’s Remicade and Simponi /[…] [decisionresourcesgroup.com]

Nitrofurantoin Toxicity

Abstract Nitrofurantoin is an antibiotic commonly used for prophylaxis and treatment of urinary tract infections. Pulmonary and hepatic toxicity are rare side effects of this agent. The simultaneous occurrence of pulmonary fibrosis and chronic active hepatitis in a patient undergoing long-term nitrofurantoin[…] [ncbi.nlm.nih.gov]

Granulomatosis with Polyangiitis

Granulomatosis with polyangiitis Other names Wegener's granulomatosis (WG) Micrograph showing features characteristic of granulomatosis with polyangiitis – a vasculitis and granulomas with multi-nucleated giant cells. H&E stain. Specialty Immunology, Rheumatology Granulomatosis with polyangiitis (GPA), previously known as[…] [en.wikipedia.org]