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20 Possible Causes for Decreased Number of Myelinated Fibers (Sural Nerve Biopsy), Personality Change

Did you mean: Decreased Number of Myelinated Fibers (Sural Nerve Biopsy, Personality Change

  • Acute Intermittent Porphyria

    Those with acute forms of porphyria develop numbness, tingling, paralysis, cramping, vomiting, constipation, personality changes or mental disorders, and/or pain in the abdomen[medicinenet.com] Open nerve and muscle biopsies showed significantly decreased numbers of myelinated fibers in the sural nerve and atrophy of type I and II fibers in the quadriceps muscle,[doi.org] During an attack, symptoms can include muscle numbness, tingling, paralysis, cramping, and personality or mental changes.[icd9data.com]

  • Neuropathy

    A person's needs often change over time, and new and alternative treatments continue to be developed.[labtestsonline.org.uk] Pathology Sural nerve biopsy reveals a marked reduction in nerve size and depletion of large and small myelinated fibers but only a slightly decreased number of unmyelinated[ncbi.nlm.nih.gov] In addition there are negative personality changes that can range from irritability and withdrawal to general excitation with pacing and picking at the skin.[ncbi.nlm.nih.gov]

  • Autonomic Neuropathy

    […] depending on a person's position, dizziness when standing, high blood pressure, and shortness of breath with activity or exercise.[healthery.com] Pathology Sural nerve biopsy reveals a marked reduction in nerve size and depletion of large and small myelinated fibers but only a slightly decreased number of unmyelinated[ojrd.biomedcentral.com] Heart and lungs autonomic neuropathy For autonomic neuropathy affecting the heart and lungs, symptoms may include an abnormal heart rate or rhythm, blood pressure changes[healthery.com]

  • Familial Dysautonomia

    Familial dysautonomia patients have recurrent crises characterized by bouts of nausea, vomiting, hypertension, tachycardia, sweating, blotching and personality changes.[ncbi.nlm.nih.gov] Pathology Sural nerve biopsy reveals a marked reduction in nerve size and depletion of large and small myelinated fibers but only a slightly decreased number of unmyelinated[doi.org] Negative personality changes range from irritability and withdrawal to general excitation.[orpha.net]

  • Dysautonomia

    People with this disorder may experience personality changes or mood disturbances, memory loss, seizures, hallucinations, or drowsiness. Encephalomyelitis.[mayoclinic.org] .: Sural nerve biopsy from a CMT1A case.[tankonyvtar.hu] The number of thick myelinated fibers decreased significantly, while concentric "onion bulb structure" is seen around the remaining fibers.[tankonyvtar.hu]

  • Hereditary Sensory Neuropathy

    In addition there are negative personality changes that can range from irritability and withdrawal to general excitation with pacing and picking at the skin.[doi.org] Pathology Sural nerve biopsy reveals a marked reduction in nerve size and depletion of large and small myelinated fibers but only a slightly decreased number of unmyelinated[doi.org] During the crisis there are cardiovascular changes including hypertension, tachycardia and blotching.[doi.org]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    In some people with this disorder, changes in personality become apparent before problems with thinking skills. [Read full article] HHS , 2011.[hsan1esociety.org] Pathologically, HSAN II demonstrates a virtual absence of myelinated fibers and a decreased number of unmyelinated fibers in sural nerve biopsies ( table 1 ).[anesthesiology.pubs.asahq.org] In some people with HSAN IE, changes in personality, such as irritability, apathy, or lack of impulse control, become apparent before problems with thinking skills.[ghr.nlm.nih.gov]

  • Xeroderma Pigmentosum

    Second, exposure to the sun and UV light leads to changes.[xpgrupoluzdeesperanza.org] (D) Representative image of sural nerve biopsy (embedded in Epon and stained with toluidine blue) from patient 1 demonstrating a decrease in the number of myelinated fibers[ng.neurology.org] […] promote premature cutaneous and ocular ageing, and in some cases promote progressive neurodegenerative changes.[ncbi.nlm.nih.gov]

  • Channelopathy-Associated Congenital Insensitivity to Pain

    In addition there are negative personality changes that can range from irritability and withdrawal to general excitation with pacing and picking at the skin.[ojrd.biomedcentral.com] Pathologically, HSAN II demonstrates a virtual absence of myelinated fibers and a decreased number of unmyelinated fibers in sural nerve biopsies ( table 1 ).[anesthesiology.pubs.asahq.org] During the crisis there are cardiovascular changes including hypertension, tachycardia and blotching.[ojrd.biomedcentral.com]

  • GM2-Gangliosidosis Variant AB

    In addition, psychic changes include anxiety, depression, insomnia, aggressiveness, severe behavioral problems, and disintegration of the personality.[78stepshealth.us] Muscle biopsy shows signs of neurogenic atrophy with type grouping and increased connective tissue. Sural nerve biopsy demonstrates decreased fiber density.[78stepshealth.us] The psychic changes may precede all other manifestations or may appear later.[78stepshealth.us]

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