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957 Possible Causes for Decreased Platelet Count, Diarrhea

  • Vitamin B12 Deficiency

    The following are the signs and symptoms of vitamin B12 deficiency: Fatigue Weight loss Palpitations Development of sore in the mouth and tongue Diarrhea Problems with menstrual[symptoma.com] Other laboratory findings associated with megaloblastic anemia include decreased white blood cell (WBC) count and platelet count.[labtestsonline.org] Symptoms of Vitamin B12 Deficiency Some don't show any symptoms of a vitamin B12 deficiency, while others may experience: Diarrhea Constipation Tiredness Light-headedness[everydayhealth.com]

  • Chronic Alcoholism

    OBJECTIVE: Diarrhea, weight loss and osteoporosis are prominent symptoms and clinical signs of alcoholism.[ncbi.nlm.nih.gov] FBC, clotting screen, renal testing and LFTs: Suspect excessive alcohol use if mean corpuscular volume (MCV) is raised and platelet count may be decreased or elevated liver[patient.info] Symptoms of the disease include anorexia, diarrhea, weight loss, neurologic and psychiatric disturbances (most notably depression), and fatty deterioration of the liver, sometimes[omicsonline.org]

  • Non-Hodgkin Lymphoma

    […] frequently reported ( 20%) adverse events of any grade in the population in which safety was studied were hyperglycemia, fatigue, and nausea (36.1% each), depression (29.2%), diarrhea[ncbi.nlm.nih.gov] The most common treatment-emergent adverse events in the GP arm were back pain (56.3%), platelet count decreased (25.0%), headache, diarrhoea, and nausea (18.8% each).[ncbi.nlm.nih.gov] Check with your doctor before you use any nonprescription medicines for your diarrhea.[uofmhealth.org]

  • Graft-versus-Host-Disease

    One male kidney transplant recipient developed diarrhea and suffered kidney function damage.[ncbi.nlm.nih.gov] His blood work showed WBC 5.21 10 9 /L (N: 92.7%), HB 80.0 g/L, and platelet count 176.0 10 9 /L. The Tac trough level was 5.4 ng/L and MPA AUC was 91.73 mg h/L.[journals.lww.com] All cases had diarrhea and pancytopenia, 4 out of 5 presented with erythematous skin rashes, and 2 had cytomegalovirus colitis.[ncbi.nlm.nih.gov]

  • Primary Immune Deficiency Disorder

    Gastrointestinal disorders, primarily manifesting in form of diarrhea, may bother up to 50% of PIDD patients.[symptoma.com] Wiskott-Aldrich Syndrome • X-linked condition • Incidence: 4:10,00,000 • Severe eczema, recurrent infections, Bloody diarrhea, chronic otitis • T cells appear bald :?[slideshare.net] […] more new ear infections within one year Two or more new sinus infections within one year, in the absence of allergy One pneumonia per year for more than one year Chronic diarrhea[immunedisease.com]

  • Multiple Myeloma

    For this reason we report this rare case in which diarrhea and abdominal pain were the initial presenting symptoms of multiple myeloma with a plasmacytoma.[ncbi.nlm.nih.gov] Decreases in blood cell counts. DARZALEX can decrease white blood cell counts which help fight infections and blood cells called platelets which help to clot blood.[darzalex.com] […] absolute neutrophil count, decreased phosphorus, anemia, neutropenia, decreased total white blood cell count, decreased platelets, diarrhea, fatigue, thrombocytopenia, pyrexia[investors.amgen.com]

  • Viral Hepatitis

    In older cattle bovine virus diarrhea (mucosal disease) is the major cause.[medical-dictionary.thefreedictionary.com] Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis[medlineplus.gov] In half of patients, diarrhea is constant; in the rest, diarrhea severity varies over time.[msdmanuals.com]

  • Hemolytic Uremic Syndrome

    Diarrhea-associated hemolytic uremic syndrome (HUS) is characterized by acute kidney injury with microangiopathic hemolytic anemia and thrombocytopenia with a diarrhea prodrome[ncbi.nlm.nih.gov] This results in platelet activation endothelial cell damage, and white blood cell activation, leading to systemic TMA, which manifests as decreased platelet count, hemolysis[en.wikipedia.org] Neurologic involvement is the most threatening complication of diarrhea-associated hemolytic uremic syndrome (D HUS).[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    The patient presented with an acute abdomen with clinical findings of acute cholecystitis, subileus, and local pain in the right upper abdomen accompanied by severe diarrhea[ncbi.nlm.nih.gov] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com] Although infections can be of any type, typical symptoms include: Fever Runny nose Cough Chest pain or shortness of breath Pain with urinating Diarrhea, occasionally Infections[ucsfhealth.org]

  • Mantle Cell Lymphoma

    Most side effects were minor and included diarrhea, fatigue, upper respiratory tract infections, nausea and rash.[sciencedaily.com] Decreased blood counts (white blood cells, platelets, and red blood cells) are common with IMBRUVICA , but can also be severe.[imbruvica.com] Two weeks after the start of ibrutinib, he developed grade 3 diarrhea that required interruption of ibrutinib.[ncbi.nlm.nih.gov]

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