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529 Possible Causes for Decreased Platelet Count, Diarrhea, Easy Bruising

  • Vitamin B12 Deficiency

    The following are the signs and symptoms of vitamin B12 deficiency: Fatigue Weight loss Palpitations Development of sore in the mouth and tongue Diarrhea Problems with menstrual[symptoma.com] It may also cause easy bruising or bleeding, including bleeding gums, gastrointestinal side effects including sore tongue, stomach upset, weight loss, and diarrhea or constipation[en.wikipedia.org] Other laboratory findings associated with megaloblastic anemia include decreased white blood cell (WBC) count and platelet count.[labtestsonline.org]

  • Chronic Alcoholism

    OBJECTIVE: Diarrhea, weight loss and osteoporosis are prominent symptoms and clinical signs of alcoholism.[ncbi.nlm.nih.gov] bruising Cardiovascular system —causing abnormal heart beat/heart rate, heart failure, high blood pressure (hypertension), and other conditions Gastrointestinal (GI) tract[healthcommunities.com] FBC, clotting screen, renal testing and LFTs: Suspect excessive alcohol use if mean corpuscular volume (MCV) is raised and platelet count may be decreased or elevated liver[patient.info]

  • Acute Myelocytic Leukemia

    The patient presented with an acute abdomen with clinical findings of acute cholecystitis, subileus, and local pain in the right upper abdomen accompanied by severe diarrhea[ncbi.nlm.nih.gov] Symptoms of AML include: Fever Shortness of breath Easy bruising or bleeding Bleeding under the skin Weakness or feeling tired Weight loss or loss of appetite Tests that examine[nlm.nih.gov] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com]

  • Multiple Myeloma

    For this reason we report this rare case in which diarrhea and abdominal pain were the initial presenting symptoms of multiple myeloma with a plasmacytoma.[ncbi.nlm.nih.gov] bruising or bleeding – due to low platelet numbers Bleeding from the nose or gums Repeated infections or infections that are hard to get rid of Thirst, nausea, vomiting or[betterhealth.vic.gov.au] Decreases in blood cell counts. DARZALEX can decrease white blood cell counts which help fight infections and blood cells called platelets which help to clot blood.[darzalex.com]

  • Hemolytic Uremic Syndrome

    Diarrhea-associated hemolytic uremic syndrome (HUS) is characterized by acute kidney injury with microangiopathic hemolytic anemia and thrombocytopenia with a diarrhea prodrome[ncbi.nlm.nih.gov] A week later, he presents to the ER with jaundice, abdominal pain, and easy bruising. Lab results come back with low platelet count, anemia, and increased creatinine.[step2.medbullets.com] This results in platelet activation endothelial cell damage, and white blood cell activation, leading to systemic TMA, which manifests as decreased platelet count, hemolysis[en.wikipedia.org]

  • Primary Myelofibrosis

    Occasionally, patients may have diarrhea related to pressure on the colon.[emedicine.medscape.com] Easy bruising or bleeding. Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com] Decreasing platelet counts in ET to below 600 x 10 9 /L can decrease thrombotic complications. 46 High platelet counts ( 1,000 x 10 9 /L) are associated with acquired von[clevelandclinicmeded.com]

  • Alcoholic Hepatitis

    Common symptoms are weakness, anorexia, weight loss, nausea, vomiting and diarrhea. Patients with alcoholic hepatitis are often malnourished and pyrexial.[euroliver.org] […] deficiency) Endocrine Gynaecomastia Testicular atrophy Loss of body hair Signs of ‘pseudo- Cushings ’ (red face, hump, striae) Face /skin Parotid enlargement Spider naevi Easy[almostadoctor.co.uk] After abstinence from alcohol, laboratory and symptomatic improvement occurred in association with a prompt increase in the platelet count and a corresponding decrease of[ncbi.nlm.nih.gov]

  • Waldenstrom Macroglobulinemia

    Tests reported noninflammatory diarrhea, severe hypoalbuminemia of 1.6 g/dL, and prolonged coagulation times.[revistagastroenterologiamexico.org] The covered platelet cells may not work right, resulting in bleeding and easy bruising. Every year, there are five new cases of macroglobulinemia per 1,000,000 people.[uihc.org] Decreased blood counts (white blood cells, platelets, and red blood cells) are common with IMBRUVICA , but can also be severe.[imbruvica.com]

  • Viral Hepatitis

    In older cattle bovine virus diarrhea (mucosal disease) is the major cause.[medical-dictionary.thefreedictionary.com] Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis[medlineplus.gov] The symptoms are similar to mild flu, and may include : Jaundice is a symptom of hepatitis. diarrhea fatigue loss of appetite mild fever muscle or joint aches nausea slight[medicalnewstoday.com]

  • Atypical Hemolytic Uremic Syndrome

    […] or bloody diarrhea.[doi.org] Thrombocytopenia can cause easy bruising and abnormal bleeding.[ghr.nlm.nih.gov] platelet count, and hemolytic anemia with schizocytes.[ncbi.nlm.nih.gov]

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