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2,522 Possible Causes for Decreased Platelet Count, Epistaxis, Susceptibility to Hematologic Malignancies Increased

  • Gaucher Disease

    Epistaxis and ecchymoses resulting from thrombocytopenia are common.[merckmanuals.com] In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[ncbi.nlm.nih.gov] Platelet Count [britannica.com] Serum Decreased Platelet Count [en.wikipedia.org] Serum Decreased Platelet Count Decreased platelet counts (thrombocytopenia) as well as low[symptoma.com]

  • Thrombocytopenia

    It presents in infancy or in neonates (in severe cases) with patients bruising easily along with further manifestations of thrombocytopenia including epistaxis, petechiae,[enerca.org] PGRN deficiency further decreased platelet count in a passive-transfer ITP murine model.[ncbi.nlm.nih.gov] Her platelet count decreased to 41   10/L, but was stable at 30   10/L for 3 months with platelet transfusion independency for 12 months.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Influenza

    RESPIRATORIO R01 Dolor atribuido al aparato respiratorio R02 Fatiga respiratoria/disnea R03 Respiración jadeante/sibilante R04 Otros problemas de la respiración R05 Tos R06 Epistaxis[iqb.es] […] leukocyte, platelet, and particularly, lymphocyte counts at the time of admission.[doi.org] La diarrea acuosa, vómito, dolor abdominal y pleural, así como epistaxis y gingivorragia son manifestaciones comunes en los estados iniciales de la enfermedad. 19,163 Algunos[scielo.org.mx]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Chronic Alcoholism

    FBC, clotting screen, renal testing and LFTs: Suspect excessive alcohol use if mean corpuscular volume (MCV) is raised and platelet count may be decreased or elevated liver[patient.info]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Chronic Kidney Insufficiency

    […] of bleeding and thrombosis in patients with renal insufficiency Bleeding Gastrointestinal bleedingBleeding from cannulation sites Retinal haemorrhage Subdural haematoma Epistaxis[academic.oup.com] […] coronary syndrome Cerebrovascular event Peripheral artery occlusion Bleeding Gastrointestinal bleedingBleeding from cannulation sites Retinal haemorrhage Subdural haematoma Epistaxis[academic.oup.com] […] increased bleeding tendency in patients with renal failure may present as gastrointestinal bleeding, bleeding from cannulation sites, retinal haemorrhage, subdural haematoma, epistaxis[academic.oup.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Disseminated Intravascular Coagulation

    […] bilateral periorbital oedema and tense orbits in keeping with orbital compartment syndrome (OCS) shortly after presenting to the emergency department for uncontrollable epistaxis[ncbi.nlm.nih.gov] Blood tests revealed a decreased platelet count, disseminated intravascular coagulation (DIC), renal dysfunction, hemolysis, and infection.[ncbi.nlm.nih.gov] Clinical history can include epistaxis, gingival bleeding, haematuria, oliguria, cough, dyspnoea, fever, delirium, and coma.[bestpractice.bmj.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Coagulation Abnormalities

    As the platelet counts are usually 50x10 9 L -1 there is an increased incidence of bruising, epistaxis and gingival bleeding.[frca.co.uk] Approximately 37% CLD cases had decreased platelet count and 15% cases had decreased serum fibrinogen level.[ncbi.nlm.nih.gov] The studies revealed an increased factor VIII level, decreased platelet count, and a short PTT.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Immune Thrombocytopenic Purpura

    An 11-year-old boy presented with epistaxis, petechial hemorrhages, easy bruising, and purpuric rash.[ncbi.nlm.nih.gov] Here we report a pediatric patient with ALL whose platelet counts decreased at the 102nd week of maintenance treatment.[ncbi.nlm.nih.gov] […] by extravasation of blood into the subcutaneous tissue, mucous membranes or skin; it generates bleeding manifestations as ecchymotic lesions, petechiae of sudden onset, epistaxis[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Portal Cirrhosis

    Reduced levels of platelets or decreased white blood cell count. Cleveland Clinic News & More Cleveland Clinic News & More[my.clevelandclinic.org] When the spleen enlarges, the number (count) of white blood cells can decrease (increasing the risk of infections), and the number (count) of platelets can decrease (increasing[merckmanuals.com] […] anemia and thrombocytopenia ( low platelet count in the bloodstream).[medicinenet.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Chronic Immune Thrombocytopenic Purpura

    The most common adverse events were headache (37%), nasopharyngitis (32%), contusion (30%), epistaxis (30%), fatigue (30%), arthralgia (25%), and diarrhea (25%).[ncbi.nlm.nih.gov] Ten patients subsequently decreased their platelet count, although they were able to attain CR after receiving six doses of anti-D (IgG)-coated RBCs.[ncbi.nlm.nih.gov] In some instances there is oral bleeding, epistaxis, rectal bleeding or haematuria. Morbidity in ITP is usually minimal and parents need to be reassured of this.[rch.org.au]

    Missing: Susceptibility to Hematologic Malignancies Increased

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