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30 Possible Causes for Decreased Platelet Count, Erythrocytes Decreased, Polychromasia in Peripheral Blood Smear

  • Autoimmune Hemolytic Anemia

    Mechanisms of actions include suppression of autoantibody production, reduction in autoantibody affinity, and decreased destruction of erythrocytes by splenic macrophages,[doi.org] Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[jahjournal.org] Median absolute reticulocyte counts decreased from 236 to 109 x 10(9)/L (P .01).[ncbi.nlm.nih.gov]

  • Microangiopathic Hemolytic Anemia

    […] than the decrease in number of erythrocytes. hypochromic microcytic anemia any anemia with microcytes that are hypochromic (reduced in size and in hemoglobin content); the[medical-dictionary.thefreedictionary.com] The peripheral blood smear revealed polychromasia, poikilocytosis, and many schistocytes. Bone marrow biopsy disclosed metastatic carcinoma.[ncbi.nlm.nih.gov] Isolated decrease in red blood cells (hemoglobin) Anemia Isolated decrease in platelets Thrombocytopenia Isolated decrease in white blood cell count Leukopenia Decrease in[morningreporttgh.blogspot.com]

  • Pancytopenia

    One mechanism indicates direct effect of CMV on bone marrow cells leading to cellular injury and decrease of erythrocytes, lymphocytes, granulocytes, and platelets.[scielo.br] blood smear examination for which Leishman stain was used.[mjdrdypu.org] counts.[njlm.net]

  • Sideroblastic Anemia

    […] protoporphyrin), decreased ferrochelatase activity, and deletion of portions of the long arms of chromosomes 18 and 20.[ncbi.nlm.nih.gov] Blood Smear Peripheral blood smear images .[imagebank.hematology.org] Erythropoietic protoporphyria (EPP) is an autosomal dominant disorder due to the decreased activity of ferrochelatase.[ommbid.mhmedical.com]

  • Hemolytic Uremic Syndrome

    Anisocytosis, poikilocytosis, polychromasia, helmet cells, marked schistocytes, and rare platelets were observed in the peripheral blood smear, compatible with microangiopathic[ziaristionline.ro] This results in platelet activation endothelial cell damage, and white blood cell activation, leading to systemic TMA, which manifests as decreased platelet count, hemolysis[en.wikipedia.org] platelet count Elevated blood urea nitrogen (BUN) and creatinine due to decreased kidney function Blood and protein in urine Presence of shiga toxin-producing E. coli in[davita.com]

  • Atypical Hemolytic Uremic Syndrome

    Additionally the compound ACH-4471 significantly decreased C3 fragment deposition on paroxysmal nocturnal hemoglobinuria erythrocytes, indicating a reduced potential relative[ncbi.nlm.nih.gov] Anisocytosis, poikilocytosis, polychromasia, helmet cells, marked schistocytes, and rare platelets were observed in the peripheral blood smear, compatible with microangiopathic[ziaristionline.ro] platelet count, and hemolytic anemia with schizocytes.[ncbi.nlm.nih.gov]

  • Hemoglobin C Disease

    erythrocyte life span Double heterozygous sickling disorder Heinz bodies Hematopoietic maturation arrest Hemoglobin A1c above reference range Hemoglobin C disease Hemoglobin[icd9data.com] Sickle and target cells, polychromasia, and sometimes Howell–Jolly bodies are detected on peripheral blood smears. Results of sickle cell solubility tests are positive.[clinchem.aaccjnls.org] These findings suggest that the hemoglobin C molecules within C-C erythrocytes exist in an aggregated state.[ncbi.nlm.nih.gov]

  • Congenital Dyserythropoietic Anemia

    We also found that erythrocyte anion exchanger 1 protein is decreased in CDA-II homozygotes and obligate carriers alike.[ncbi.nlm.nih.gov] Anisopoikilocytosis with tear-drop forms, polychromasia, basophilic stippling in peripheral blood smear, erythroid hyperplasia with megaloblastoid changes, binucleated cells[ncbi.nlm.nih.gov] Platelet counts increased to maximal values of 1200 10 9 /L, and in some cases platelet counts remained elevated for many years.[doi.org]

  • Uremic Anemia

    […] in 38 hemodialysed patients was decreased and urea, creatinine and middle molecular substances had the effect on decreasing the osmotic resistance of erythrocyte in vitro[jstage.jst.go.jp] A peripheral blood smear showed red blood cell fragmentation with a few schistocytes (asterisk, 6/high power field) and polychromasia (arrow).[synapse.koreamed.org] platelet count Elevated blood urea nitrogen (BUN) and creatinine due to decreased kidney function Blood and protein in urine Presence of shiga toxin-producing E. coli in[davita.com]

  • Cold Agglutinin Disease

    The RBC count will be decreased due to doublet erythrocytes being counted as a single cell, thus resulting in a falsely high MCV. Hematocrit will also be lowered.[keralamedicaljournal.com] Reticulocytes and Spherocytes The results of the reticulocyte count are usually increased in patients with cold agglutinin disease, with polychromasia in the peripheral blood[web.archive.org] Leukocyte and platelet counts were also found to be unaffected by cold agglutinins.[biochemia-medica.com]

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