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2,153 Possible Causes for Decreased Platelet Count, Fatigue, Peripheral Neuropathy, Thrombocytopenia, Tongue Atrophy

  • Vitamin B12 Deficiency

    thrombocytopenia were improved by vitamin B12 supplementation alone, with a single session of plasma exchange.[ncbi.nlm.nih.gov] The clinical symptoms are weakness, fatigue, shortness of breath and neurologic abnormalities.[ncbi.nlm.nih.gov] Other laboratory findings associated with megaloblastic anemia include decreased white blood cell (WBC) count and platelet count.[labtestsonline.org] Participation included measuring vitamin B12 levels and assessing peripheral neuropathy using Neuropathy Total Symptom Score-6 (NTSS-6) questionnaire.[ncbi.nlm.nih.gov] […] deficiency ranges from the incidental increase of mean corpuscular volume and neutrophil hypersegmentation to symptoms due to severe anemia, such as angor, dyspnea on exertion, fatigue[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Corticosteroids may have a role in hastening resolution of some complications, especially upper airway obstruction and possibly immune-mediated anemia and thrombocytopenia[dx.doi.org] Fatigue can sometimes persist for longer. In most people, fatigue will end after three months.[web.archive.org] , which is a decrease in platelets, the part of your blood that begins the clotting process inflammation of the heart complications that involve the nervous system, such as[healthline.com] Neurologic complications are rare but may include encephalitis, seizures, Guillain-Barré syndrome, peripheral neuropathy, viral meningitis, myelitis, cranial nerve palsies[merck.com] A diagnosis of acute symmetrical sensorimotor peripheral neuropathy (Guillain-Barré syndrome) was made. The results of CSF cultures were negative.[dx.doi.org]

    Missing: Tongue Atrophy
  • Chronic Alcoholism

    Leukopenia and Thrombocytopenia due to direct bone marrow effect, but also from cirrhosis/splenomegaly.[errolozdalga.com] Chronic alcoholism can affect the circulatory system, increase the risk of anemia and lead to complaints like fatigue, breathlessness and lightheadedness .[epainassist.com] FBC, clotting screen, renal testing and LFTs: Suspect excessive alcohol use if mean corpuscular volume (MCV) is raised and platelet count may be decreased or elevated liver[patient.info] A consecutive sample of 62 chronic alcoholics was studied, 18 females and 44 males, aged between 28 and 69 years to assess the incidence and distribution of peripheral neuropathy[ncbi.nlm.nih.gov] In chronic alcoholism, macrocytosis, thrombocytopenia, prolonged PT, elevated GGT, hyperuricaemia or hypertriglyceridaemia may be found.[rcpa.edu.au]

    Missing: Tongue Atrophy
  • Pernicious Anemia

    This is the second description of pernicious anemia associated with autoimmune thrombocytopenia.[ncbi.nlm.nih.gov] Signs and Symptoms of Anemia The most common symptom of all types of anemia is fatigue (tiredness).[web.archive.org] , making the tongue look smooth and shiny, and neuroanemic syndrome.[doi.org] Cobalamin deficiency–related neurological impairment can vary in clinical presentation, including acute combined system degeneration, peripheral neuropathy, and psychosis.[emedicine.medscape.com] Pernicious Anemia Macrocytic anemia, glossitis, peripheral neuropathy, weakness, hyperreflexia, ataxia, and other neurological manifestations characterize classical vitamin[clinlabnavigator.com]

  • Systemic Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[ncbi.nlm.nih.gov] Medication usage did not predict fatigue levels. Pain and depression were both unique positive predictors of fatigue.[ncbi.nlm.nih.gov] […] blood cell count (leukopenia), decrease in lymphocytes (lymphopenia), or decrease in blood platelets ( thrombocytopenia ).[webmd.com] neuropathy.[ncbi.nlm.nih.gov] Inflammation of the lining around the lungs (pleuritis) or of the lining around the heart (pericarditis) Blood disorder, either low red blood cell count ( anemia ), low white[webmd.com]

    Missing: Tongue Atrophy
  • Leukemia

    Anemia and thrombocytopenia are the major adverse prognostic variables. CLL has no standard staging system.[web.archive.org] Evidence-based treatment for cancer-related fatigue. J Natl Cancer Inst Monogr. 2004 ;32: 112 - 118.[doi.org] The number of platelets on a blood count will be below normal. Thrombocytopenia is the term used for a decreased number of platelets. Recurrent infections.[stanfordchildrens.org] Peripheral neuropathyPeripheral neuropathy, or numbness, tingling or pain in the hands and feet, can last months after therapy with agents such as Oncovin.[hopkinsmedicine.org] CASE PRESENTATION: We report a case of a 53 year old patient with T-LGL, Immune-Thrombocytopenia (ITP) and combined antibody deficiency, who presented with fever and reduced[ncbi.nlm.nih.gov]

    Missing: Tongue Atrophy
  • Gaucher Disease

    KEYWORDS: GBA gene mutation; Gaucher cells; thrombocytopenia; type 1 Gaucher disease[ncbi.nlm.nih.gov] Hematologic changes, bone pain, hepatomegaly, splenomegaly, and fatigue were the most recurrent signs and symptoms.[ncbi.nlm.nih.gov] [britannica.com] Serum Decreased Platelet Count [en.wikipedia.org] Serum Decreased Platelet Count Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia[symptoma.com] Comorbidities for peripheral neuropathy were excluded.[ncbi.nlm.nih.gov] Fatigue prolonged bleeding fever, chills, sweating seizure developmental delay Orthopaedics Bone fractures/osteomyelitis joint pain/contractures bone necrosis/ osteonecrosis[brainscape.com]

    Missing: Tongue Atrophy
  • Multiple Myeloma

    Moreover, there was much more largely decreased incidence of grade 3 and higher thrombocytopenia and BIPN in bortezomib SC administration than IV route.[ncbi.nlm.nih.gov] She developed G2 AEs, including nausea and fatigue. The cardiac amyloidosis worsened, and she died of heart and renal failure.[ncbi.nlm.nih.gov] Decreases in blood cell counts. DARZALEX can decrease white blood cell counts which help fight infections and blood cells called platelets which help to clot blood.[darzalex.com] The mechanism of the development of the peripheral neuropathy is poorly understood.[ncbi.nlm.nih.gov] […] absolute neutrophil count, decreased phosphorus, anemia, neutropenia, decreased total white blood cell count, decreased platelets, diarrhea, fatigue, thrombocytopenia, pyrexia[investors.amgen.com]

    Missing: Tongue Atrophy
  • Chronic Lymphocytic Leukemia

    Anemia and thrombocytopenia are the major adverse prognostic variables. CLL has no standard staging system.[web.archive.org] Symptoms of CLL may include: Abnormal bruising (if platelets are low) Enlarged lymph nodes, liver, or spleen Excessive sweating, night sweats Fatigue Fever Infections that[nlm.nih.gov] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com] I had bad peripheral neuropathy of the legs after using a small dose of vincristine in 2007; Dr.[clldiary.blogspot.com] Decrease in blood cell counts. Decreased blood counts (white blood cells, platelets, and red blood cells) are common with IMBRUVICA , but can also be severe.[imbruvica.com]

    Missing: Tongue Atrophy
  • Acute Myelocytic Leukemia

    The consolidation treatment was the same in both arms but caused significantly more leukopenia and thrombocytopenia in patients previously treated with HIDAC-3-7 induction[ncbi.nlm.nih.gov] Symptoms include anemia, fatigue, weight loss, easy bruising, thrombocytopenia, and granulocytopenia that leads to persistent bacterial infections.[medical-dictionary.thefreedictionary.com] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com] Sleep Better to Feel Better: Tips You Can Use Helping Teachers and Educators Support Siblings of Children with Cancer Understanding Peripheral Neuropathy Survivors Too: Family[cancercare.org] The clinical presentation was similar in all three, with acute onset of hepatomegaly and thrombocytopenia in the absence of significant transaminasemia or icterus.[ncbi.nlm.nih.gov]

    Missing: Tongue Atrophy

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