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3,042 Possible Causes for Decreased Platelet Count, Fatigue, Peripheral Neuropathy, Thrombocytopenia, Tongue Atrophy

  • Infectious Mononucleosis

    A 49-year-old man with diabetic mellitus suffered from IM with fever, pharyngitis, parotiditis with lymphadenopathies, thrombocytopenia and splenomegaly.[ncbi.nlm.nih.gov] […] infectious mononucleosis (IM), including issues of diagnosis, the determination of splenomegaly, and other measures of disease status, the relationship of the disease to chronic fatigue[ncbi.nlm.nih.gov] Rare complications According to the Mayo Clinic, mono can also cause some of these extremely rare complications: anemia , which is a decrease in your red blood cell count[healthline.com] Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov] An autoimmune hemolytic anemia or thrombocytopenia may also occur. N.B.[askhematologist.com]

    Missing: Tongue Atrophy
  • Gaucher Disease

    Medical examination showed slight splenomegaly (250 62 mm), thrombocytopenia (platelets 51 109/L), anemia (Hb levels 107 g/L), and β-glucocerebrosidase activity (GBA) in leukocytes[ncbi.nlm.nih.gov] Hematologic changes, bone pain, hepatomegaly, splenomegaly, and fatigue were the most recurrent signs and symptoms.[ncbi.nlm.nih.gov] Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia) and decreased white blood cell counts (leukopenia) result in easy bruisability and hence black-and-blue[scientificamerican.com] Comorbidities for peripheral neuropathy were excluded.[ncbi.nlm.nih.gov] […] blood cell count causing anemia Individuals with anemia may have fatigue, low energy, and decreased exercise tolerance Decreased platelet count can cause easy bruising Bone[dovemed.com]

    Missing: Tongue Atrophy
  • Multiple Myeloma

    Moreover, there was much more largely decreased incidence of grade 3 and higher thrombocytopenia and BIPN in bortezomib SC administration than IV route.[ncbi.nlm.nih.gov] She developed G2 AEs, including nausea and fatigue. The cardiac amyloidosis worsened, and she died of heart and renal failure.[ncbi.nlm.nih.gov] Patients may also have: Anemia (low red blood cell count) Leukopenia (low white blood cell count) Thrombocytopenia (low platelet count) Hypercalcemia (high calcium level in[orthoinfo.aaos.org] The mechanism of the development of the peripheral neuropathy is poorly understood.[ncbi.nlm.nih.gov] He was intubated and shifted to the intensive care unit with the diagnosis of acute pancreatitis with hypercalcemia and an elevated amylase and lipase's well as thrombocytopenia[ncbi.nlm.nih.gov]

    Missing: Tongue Atrophy
  • Leukemia

    Patients with the BRAF V600E mutation had a significantly higher frequency of neutropenia, thrombocytopenia, and elevated soluble interleukin-2 receptor and common B-cell[ncbi.nlm.nih.gov] A 21-year-old woman who presented fatigue had a new diagnosis of acute lymphoblastic leukemia underwent FDG PET/CT.[ncbi.nlm.nih.gov] The number of platelets on a blood count will be below normal. Thrombocytopenia is the term used for a decreased number of platelets. Recurrent infections.[stanfordchildrens.org] Peripheral neuropathyPeripheral neuropathy, or numbness, tingling or pain in the hands and feet, can last months after therapy with agents such as Oncovin.[hopkinsmedicine.org] We report a case of a 53 year old patient with T-LGL, Immune-Thrombocytopenia (ITP) and combined antibody deficiency, who presented with fever and reduced general condition[ncbi.nlm.nih.gov]

    Missing: Tongue Atrophy
  • Systemic Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[ncbi.nlm.nih.gov] The protocol will be valuable to research groups planning clinical trials targeting fatigue in PBC and also transferrable to other conditions associated with fatigue.[cortjohnson.org] […] blood cell count (leukopenia), decrease in lymphocytes (lymphopenia), or decrease in blood platelets ( thrombocytopenia ).[webmd.com] GBS is an autoimmune peripheral neuropathy usually triggered by an antecedent bacterial or viral infection, with SLE being a rare cause.[ncbi.nlm.nih.gov] Neurologic system involvement may create painful peripheral neuropathy or headache syndromes. Raynaud’s phenomenon occurs in many people with SLE and can be painful.[practicalpainmanagement.com]

    Missing: Tongue Atrophy
  • Vitamin B12 Deficiency

    […] lactate dehydrogenase, vasoconstriction, increased platelet aggregation, and abnormal activation of the coagulation followed by microangiopathy as well as neutropenia and thrombocytopenia[ncbi.nlm.nih.gov] The clinical symptoms are weakness, fatigue, shortness of breath and neurologic abnormalities.[ncbi.nlm.nih.gov] Those with NTSS-6 scores 6 were considered to have peripheral neuropathy.[ncbi.nlm.nih.gov] […] hypoproliferative megaloblastic anemia with hemolysis (hemoglobin 61g/L, mean corpuscular volume 99fL, reticulocytes 0.8%, haptoglobin undetectable), leukopenia (2.7 109/L), thrombocytopenia[ncbi.nlm.nih.gov] […] patients were; infections in 30 %, pallor in 25 %, hypotonia and neuro-developmental delay in 25 %, refusal to solid food or to suck in 20 %, failure to thrive in 15 %, fatigue[ncbi.nlm.nih.gov]

  • Serum Sickness

    Post-partum, she developed thrombocytopenia, with a platelet nadir of 4000 mm 3 , also thought to be autoimmune in nature, although not associated with usual lupus flare symptomatology[academic.oup.com] Provide periods of rest to promote sleep and decrease fatigue. Organize patient care and activities to provide uninterrupted rest. Perform hand hygiene.[quizlet.com] neuropathy or brachial neuritis.[n.neurology.org] Still have flare up of rash with heat, headache, all over joint pain and lots of fatigue- still on the 60 mg of Prednisone a day.[kickas.org] Workup Laboratory findings may include neutropenia, mild thrombocytopenia, elevated ESR/CRP, mild proteinuria, AKI, and decreased complement levels.[sinaiem.org]

    Missing: Tongue Atrophy
  • Acute Lymphoblastic Leukemia

    This bleeding is commonly attributed to thrombocytopenia due to bone marrow suppressive chemotherapeutic agents.[ncbi.nlm.nih.gov] A 21-year-old woman who presented fatigue had a new diagnosis of acute lymphoblastic leukemia underwent FDG PET/CT.[ncbi.nlm.nih.gov] After 16 months, the results of routine blood tests showed reduced hemoglobin levels and decreased platelet counts.[ncbi.nlm.nih.gov] Chemotherapy-induced Peripheral Neuropathy (CIPN) of large-fibers affects up to 20% of survivors of pediatric acute lymphoblastic leukemia (ALL).[ncbi.nlm.nih.gov] The index patient achieved durable complete remission without transplantation but had persistent moderate thrombocytopenia without bleeding tendency.[ncbi.nlm.nih.gov]

    Missing: Tongue Atrophy
  • Acute Myelocytic Leukemia

    The clinical presentation was similar in all three, with acute onset of hepatomegaly and thrombocytopenia in the absence of significant transaminasemia or icterus.[ncbi.nlm.nih.gov] Symptoms include anemia, fatigue, weight loss, easy bruising, thrombocytopenia, and granulocytopenia that leads to persistent bacterial infections.[medical-dictionary.thefreedictionary.com] Sleep Better to Feel Better: Tips You Can Use Helping Teachers and Educators Support Siblings of Children with Cancer Understanding Peripheral Neuropathy Survivors Too: Family[cancercare.org] During the postoperative course, both respiratory failure and severe thrombocytopenia progressed.[ncbi.nlm.nih.gov] Bleeding Bleeding is present due to the decreased platelet counts or due to DIC. DIC is predominantly seen in acute promyelocytic leukemia (M3).[lecturio.com]

    Missing: Tongue Atrophy
  • Chronic Lymphocytic Leukemia

    There is no or little evidence of anemia or thrombocytopenia.[symptoma.com] Common adverse events were neutropenia, diarrhea, nausea, anemia, upper respiratory tract infection, thrombocytopenia, and fatigue.[ncbi.nlm.nih.gov] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com] We describe a case of a 77-year-old man who presented with fatigue, pallor and lower limb pain and weakness.[ncbi.nlm.nih.gov] Some patients notice fatigue, enlargement of lymph nodes or fullness in the abdomen due to an enlarged spleen.[ucsfhealth.org]

    Missing: Tongue Atrophy

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