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256 Possible Causes for Decreased Platelet Count, Hepatosplenomegaly, Infectious Mononucleosis

  • Infectious Mononucleosis

    Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[ncbi.nlm.nih.gov] infectious mononucleosis after further examination.[symptoma.com] , which is a decrease in platelets, the part of your blood that begins the clotting process inflammation of the heart complications that involve the nervous system, such as[healthline.com]

  • Acute Leukemia

    Physical examination showed jaundice, hepatosplenomegaly, and peripheral facial nerve palsy in addition to dermal nodules.[ncbi.nlm.nih.gov] Epstein-Barr virus (EBV), which is usually responsible for infectious mononucleosis, has been linked to ALL and Burkitt’s lymphoma.[healthline.com] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com]

  • Cytomegalovirus Infection

    […] should arouse suspicion of intrauterine CMV infection can be distinguished into CNS signs such as ventriculomegaly or microcephaly and extracerebral infection signs such as hepatosplenomegaly[ncbi.nlm.nih.gov] A syndrome that is similar to infectious mononucleosis but lacks severe pharyngitis is common.[msdmanuals.com] Based on univariate logistic regression, odds ratios for a poor outcome were 1.24, 7.2, 22.5 and 25.5 for each 10,000-mm 3 decrease in platelet count Dreux et al. [ 102 ][karger.com]

  • Babesiosis

    Jaundice, hepatosplenomegaly, anemia and conjugated hyperbilirubinemia developed in this preterm infant.[ncbi.nlm.nih.gov] […] terms) and infectious mononucleosis.[orpha.net] These include: Decreased red blood cells, hemoglobin and hematocrit Decreased platelet numbers (thrombocytopenia) Normal or slightly decreased white blood cell count Comprehensive[labtestsonline.org]

  • Autoimmune Hemolytic Anemia

    A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] Cold type autoimmune hemolytic anemia is a rare manifestation of infectious mononucleosis and serum ferritin is used very rarely as an important biomarker.[ncbi.nlm.nih.gov] Median absolute reticulocyte counts decreased from 236 to 109 x 10(9)/L (P .01).[ncbi.nlm.nih.gov]

  • Hodgkin Lymphoma

    We report a case of an 18-year-old man, who presented with fever and was found to have pallor, generalised lymphadenopathy, hepatosplenomegaly, ascites and pedal oedema.[ncbi.nlm.nih.gov] We present a 21-year-old male patient with a history of EBV-related infectious mononucleosis in puberty and Hodgkin's disease two years previously treated with irradiation[ncbi.nlm.nih.gov] Physical examination revealed a cachectic male with pallor, with enlarged left supraclavicular Virchow's lymph node and hepatosplenomegaly.[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    Hepatosplenomegaly can come and go with disease activity.[ojrd.biomedcentral.com] We describe a 14-year-old girl who presented with acute onset of SLE concurrently with clinical and laboratory findings consistent with EBV-induced infectious mononucleosis[ncbi.nlm.nih.gov] […] blood cell count (leukopenia), decrease in lymphocytes (lymphopenia), or decrease in blood platelets ( thrombocytopenia ).[webmd.com]

  • Castleman Disease

    For multicentric disease: multi-region CT bilateral hilar and mediastinal lymphadenopathy centrilobular nodules diffuse abdominal lymphadenopathy hepatosplenomegaly ascites[radiopaedia.org] mononucleosis or chronic active EBV (Detectable EBV viral load not necessarily exclusionary) †Inflammation and adenopathy due to other uncontrolled infections, e.g. acute[raredr.com] The observed side effects were low platelet counts and low fibrin levels, with no macrophage activation syndrome ( Fig. 1 ) and an episode of herpes zoster.[mct.aacrjournals.org]

  • Leukemia

    […] lymphocytic leukemia is a rare form of leukemia, caused by clonal proliferation of cytotoxic T-cells, characterized by modest lymphocytosis and cytopenias of other lineage with hepatosplenomegaly[ncbi.nlm.nih.gov] mononucleosis-like PTLD 9971/1 Polymorphic PTLD 9971/3 Monomorphic PTLD (B- and T/NK-cell types, classified according to the leukemia/lymphomato which they correspond) -[atlasgeneticsoncology.org] Decrease in blood cell counts. Decreased blood counts (white blood cells, platelets, and red blood cells) are common with IMBRUVICA , but can also be severe.[imbruvica.com]

  • Primary Immune Deficiency Disorder

    […] not absent T-cell function and normal or elevated immunoglobulins Autosomal recessive or X-linked NEMO Common and opportunistic infections, lymphopenia, lymphadenopathy, hepatosplenomegaly[merckmanuals.com] Acquired agammaglobulinemia after a life-threatening illness with clinical and laboratory features of infectious mononucleosis in three related male children.[rarediseases.org] Examples of types of infections that can lead to immunodeficiency are chickenpox, cytomegalovirus, German measles, measles, tuberculosis, infectious mononucleosis (Epstein-Barr[medical-dictionary.thefreedictionary.com]

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