Create issue ticket

1,008 Possible Causes for Decreased Platelet Count, Hypoglycemia, Leukopenia, Thrombocytopenia

  • Propionic Acidemia

    Severe thrombocytopenia is the hallmark of the metabolic crisis.[ncbi.nlm.nih.gov] […] propionyl-CoA carboxylase deficiency glycinemia, ketotic ketotic hyperglycinemia PROP Propionicacidemia PROPIONIC ACIDEMIA Pcc Deficiency Hyperglycinemia With Ketoacidosis and Leukopenia[wikidata.org] It is frequently accompanied by metabolic acidosis with anion gap, ketonuria, hypoglycemia, hyperammonemia, and cytopenias.[ncbi.nlm.nih.gov] They also had leukopenia and thrombocytopenia, and two of them had anorectal malformations, one an imperforate anus with rectoperineal fistula, and the other an ectopic anus[ncbi.nlm.nih.gov]

  • Plasmodium Falciparum Malaria

    Statistics from Altmetric.com Plasmodium falciparum malaria thrombocytopenia traveller Thrombocytopenia is frequent in patients with acute malaria and is sometimes profound[adc.bmj.com] Fever (100%), splenomegaly (86.7%), hepatomegaly (26.7%), leukopenia (13.3%), thrombocytopenia (80%), elevated liver function tests (40%), and increased serum creatinine levels[ncbi.nlm.nih.gov] Other manifestations of P falciparum infection include hypoglycemia, lactic acidosis, severe anemia, and multiorgan dysfunction due to hypoxia.[emedicine.medscape.com] PFM treatment consists in antiparasitic therapy and possibly additional measures that remedy complications like anemia, acidosis, hypoglycemia and seizures.[symptoma.com]

  • Infectious Mononucleosis

    They include Granulocytopenia Thrombocytopenia Hemolytic anemia Transient mild granulocytopenia or thrombocytopenia occurs in about 50% of patients; severe cases, associated[merck.com] Rare complications According to the Mayo Clinic, mono can also cause some of these extremely rare complications: anemia , which is a decrease in your red blood cell count[healthline.com] Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov] […] protein in red blood cells Thrombocytopenia — a low count of platelets, which are blood cells involved in clotting Heart problems — an inflammation of the heart muscle (myocarditis[mayoclinic.com]

    Missing: Hypoglycemia
  • Isovaleric Acidemia

    This report concerns an infant who presented at 10 days of age because of lethargy, poor feeding, hypothermia, cholestasis, and thrombocytopenia, leukopenia, and profound[ncbi.nlm.nih.gov] […] branched-chain amino-acid metabolism, Disturbances of metabolism of leucine, isoleucine, and valine, Hypervalinemia Intermittent branched-chain ketonuria, Leucine-induced hypoglycemia[genedx.com] Laboratory features included hyperglycemia, hyperammonemia, hyperamylasemia, hypocalcemia, neutropenia, thrombocytopenia and subsequent anemia.[ncbi.nlm.nih.gov] Leukopenia MedGen UID: 6073 • Concept ID: C0023530 • Disease or Syndrome A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[ncbi.nlm.nih.gov] […] blood cell count (leukopenia), decrease in lymphocytes (lymphopenia), or decrease in blood platelets ( thrombocytopenia ).[webmd.com] Drugs causing leukopenia Some drugs may lead to leukopenia.[news-medical.net] In a large cohort of pediatric patients with T1DM, no difference was observed in hemoglobin A1C (HbA1C) levels, frequency of ketoacidosis, hypoglycemia, or need for increased[dx.doi.org]

  • Chronic Alcoholism

    Leukopenia and Thrombocytopenia due to direct bone marrow effect, but also from cirrhosis/splenomegaly.[errolozdalga.com] FBC, clotting screen, renal testing and LFTs: Suspect excessive alcohol use if mean corpuscular volume (MCV) is raised and platelet count may be decreased or elevated liver[patient.info] Alcoholism & Hypoglycemia Alcoholism is the enhanced consumption of ethanol ( 120ml/day) and hypoglycemia is a condition where there is decreased blood glucose levels ( [[pubs.sciepub.com] In chronic alcoholism, macrocytosis, thrombocytopenia, prolonged PT, elevated GGT, hyperuricaemia or hypertriglyceridaemia may be found.[rcpa.edu.au]

  • Acute Lymphoblastic Leukemia

    This bleeding is commonly attributed to thrombocytopenia due to bone marrow suppressive chemotherapeutic agents.[ncbi.nlm.nih.gov] CASE REPORT We report the case of a 58-year-old male patient who presented with severe chest pain, dyspnea, systemic symptoms, leukopenia, normocytic anemia, and severe lactic[ncbi.nlm.nih.gov] OUTCOMES: After 16 months, the results of routine blood tests showed reduced hemoglobin levels and decreased platelet counts.[ncbi.nlm.nih.gov] Other laboratory findings may include hyperuricemia, hyperphosphatemia, hyperkalemia or hypokalemia, hypocalcemia, elevated serum hepatic transaminases or LDH, hypoglycemia[web.archive.org]

  • Pegylated Interferon Alfa

    All 12 patients experienced at least one adverse event during treatment: two (17%) patients experienced anaemia, eight (67%) neutropenia, and ten (83%) thrombocytopenia.[ncbi.nlm.nih.gov] Virologic responders (SVR, relapse, and breakthrough) experienced greater maximum decreases from baseline in hemoglobin level, neutrophil count, platelet count, and weight[ncbi.nlm.nih.gov] Anemia, neutropenia, leukopenia, and thrombcytopenia were 11%, 32%, 52%, and 5%, respectively.[ncbi.nlm.nih.gov] […] interstitial nephritis, thyroiditis, and systemic lupus erythematosus reported May cause or aggravate endocrine disorders including hypothyroidism, hyperthyroidism, hyperglycemia, hypoglycemia[reference.medscape.com]

  • Fetal Erythroblastosis

    Schistocytes, as a sign of disseminated intravascular coagulation and burr cells, are present, as well as neutropenia and thrombocytopenia.[symptoma.com] The transfusion of neutrophil-specific antibodies causes leukopenia and a broad spectrum of pulmonary reactions. Transfusion . 2007 Mar. 47(3):545-50. [Medline] .[emedicine.medscape.com] Five of the infants developed hypoglycemia prior to exchange transfusion (ET).[nature.com] Management of severe alloimmune thrombocytopenia in the newborn. Arch Dis Child Fetal Neonatal Ed 2000 ; 82 : F173 –5. Ohlsson A , Lacy JB.[doi.org]

  • Malignant Histiocytosis

    The terminal event was characterized by fever, hepatosplenomegaly, thrombocytopenia, and a leukemic blood picture.[ncbi.nlm.nih.gov] Two years later, he manifested persistent fever, leukopenia, effusions and hypoproteinemia, and his general condition worsened progressively.[ncbi.nlm.nih.gov] […] scan indications may be ordered as part of pre-treatment staging findings shows increased uptake in adjacent cortex Studies Labs elevated WBC eosinophilia abnormal LFTs hypoglycemia[orthobullets.com] In case 2 the diagnosis was initially idiopathic thrombocytopenia purpura but he deteriorated on steroids, and was subsequently unsuccessfully treated with chemotherapy and[ncbi.nlm.nih.gov]

Similar symptoms