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5,402 Possible Causes for Decreased Platelet Count, Jaundice, Susceptibility to Hematologic Malignancies Increased

  • Gaucher Disease

    Investigations General assessment FBC and differential (assess the degree of pancytopenia); LFTs (minor elevations of liver enzymes are common but jaundice is a poor prognostic[patient.info] In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[ncbi.nlm.nih.gov] Platelet Count [britannica.com] Serum Decreased Platelet Count [en.wikipedia.org] Serum Decreased Platelet Count Decreased platelet counts (thrombocytopenia) as well as low[symptoma.com]

  • Vitamin B12 Deficiency

    We report an adolescent girl who presented with jaundice and weight loss for 6 months secondary to vitamin B12 deficiency, leading to megaloblastic anaemia.[ncbi.nlm.nih.gov] Other laboratory findings associated with megaloblastic anemia include decreased white blood cell (WBC) count and platelet count.[labtestsonline.org] Jaundice Most of us have only heard of jaundice in reference to newborn babies, who are occasionally born with this condition, in which skin and eyes may take on a yellow[healthyway.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Chronic Alcoholism

    A rare syndrome defined by a rapid decline in hepatic function, characterised by jaundice, coagulopathy (INR 1.5), and hepatic encephalopathy in patients with no evidence[bestpractice.bmj.com] FBC, clotting screen, renal testing and LFTs: Suspect excessive alcohol use if mean corpuscular volume (MCV) is raised and platelet count may be decreased or elevated liver[patient.info] Jaundice lessens as liver function improves.[dermnetnz.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Infectious Mononucleosis

    We report a case of infectious mononucleosis in a 72-year old jaundiced gentleman with ferritin level of 2438 that normalised on clinical improvement.[ncbi.nlm.nih.gov] , which is a decrease in platelets, the part of your blood that begins the clotting process inflammation of the heart complications that involve the nervous system, such as[healthline.com] […] patient between 16 and 25 years old who complains of sore throat and fever is more likely to have infectious mononucleosis than another disease; and if - in addition - he is jaundiced[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Portal Cirrhosis

    It has a lengthy latent period, usually followed by the sudden appearance of abdominal pain and swelling, hematemesis, dependent edema, or jaundice.[medical-dictionary.thefreedictionary.com] Reduced levels of platelets or decreased white blood cell count. Cleveland Clinic News & More Cleveland Clinic News & More[my.clevelandclinic.org] When the spleen enlarges, the number (count) of white blood cells can decrease (increasing the risk of infections), and the number (count) of platelets can decrease (increasing[merckmanuals.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Hereditary Spherocytosis

    This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist[ncbi.nlm.nih.gov] Postoperative markedly elevated platelet count was maintained up to 6 months, and after that, platelet count gradually decreased to normal values.[ncbi.nlm.nih.gov] At the age of 10 months after confirming stability of platelet counts, tapering betamethasone resulted in gradually decreasing hemoglobin levels and platelet counts (hemoglobin[jhoonline.biomedcentral.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Liver Failure

    Rare disease associated with jaundice, coagulopathy, and hepatic encephalopathy.[bestpractice.bmj.com] Blood examination and imaging revealed a decreased platelet count and splenomegaly.[ncbi.nlm.nih.gov] Other complications from cirrhosis include: bruising (due to low platelet count and/or poor clotting) bleeding (due to decreased clotting proteins) sensitivity to medications[healthline.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Pernicious Anemia

    Jaundice: There is mild jaundice caused by the excessive breakdown of hemoglobin due to ineffective erythropoiesis in the bone marrow.[symptoma.com] RBC and WBC counts are low. Platelet count is low. Red blood cell indices are usually normal.[labtestsonline.org] She was readmitted with jaundice and macrocytic anemia.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Septicemia

    Jaundice What other disease/condition shares some of these symptoms?[clinicaladvisor.com] count that decreased to less than 30,000 per cubic millimeter and remained at that level despite standard therapy, traumatic injury of a blood vessel, or traumatic injury[content.nejm.org] […] accumulation Impaired oxygenation PaO 2 /FIO 2 Mechanical ventilation with low tidal volume and PEEP Liver Disturbed intracellular and extracellular bile salt transport Jaundice[doi.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Ascending Cholangitis

    Indeed, the presence of a complete Charcot's triad ranges from 15.4–72.0%, which is why fever and jaundice remain the most important features.[symptoma.com] The outcomes of patients with cholestatic jaundice depend on the cause.[ncbi.nlm.nih.gov] The bile flow is stanched and the patient will become jaundiced.[buckeyesurgeon.com]

    Missing: Susceptibility to Hematologic Malignancies Increased

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