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139 Possible Causes for Decreased Platelet Count, Normocytic Normochromic Anemia

  • Chronic Kidney Insufficiency

    Hyperphosphatemia and hyperparathyroidism are common findings, whereas a complete blood count (CBC) reveals anemia with normochromic and normocytic characteristics, thus excluding[symptoma.com] The anemia of CKD is normochromic-normocytic, with an Hct of 20 to 30% (35 to 40% in patients with polycystic kidney disease ).[merckmanuals.com] Anemia is characteristic of moderate to advanced CKD ( stage 3).[merckmanuals.com]

  • Multiple Myeloma

    […] typically normochromic/normocytic renal failure proteinuria hypercalcemia Presentation may also be with a complication, including: pathological fracture vertebral compression[radiopaedia.org] Decreases in blood cell counts. DARZALEX can decrease white blood cell counts which help fight infections and blood cells called platelets which help to clot blood.[darzalex.com] […] absolute neutrophil count, decreased phosphorus, anemia, neutropenia, decreased total white blood cell count, decreased platelets, diarrhea, fatigue, thrombocytopenia, pyrexia[investors.amgen.com]

  • Autoimmune Hemolytic Anemia

    Signs and Symptoms Pallor Jaundice Lethargy Abdominal pain Low-grade fever Dark urine (sever hemolysis) Hepatosplenomegaly Diagnostic tests CBC with smear Normocytic, normochromic[pedclerk.bsd.uchicago.edu] Median absolute reticulocyte counts decreased from 236 to 109 x 10(9)/L (P .01).[ncbi.nlm.nih.gov] anemia Reticulocytosis (or rare reticulocytopenia) Spherocytes, schistocytes, poikilocytes, polychromasia Normal WBC and Platelets (except in Evan’s syndrome) DAT (Direct[pedclerk.bsd.uchicago.edu]

  • Paroxysmal Nocturnal Hemoglobinuria

    RESULTS: We observed a decrease in platelet EV count with eculizumab treatment (p CONCLUSIONS: Eculizumab has an impact on the extent of EV production and on the procoagulant[ncbi.nlm.nih.gov] As many patients had increased platelet counts as had decreased platelet counts.[bloodjournal.hematologylibrary.org] […] in platelet count by 25% or more compared to baseline or the peak platelet count during Soliris treatment; an increase in serum creatinine by 25% or more compared to baseline[soliris.net]

  • Diffuse Scleroderma

    OBJECTIVES: To assess the long-term efficacy and tolerability of mycophenolate mofetil (MMF) in patients with diffuse cutaneous systemic sclerosis (dcSSc). METHODS: Patients enrolled in the Australian Scleroderma Cohort study with dcSSc and baseline modified Rodnan skin score (mRSS) 12 who were treated for a[…][ncbi.nlm.nih.gov]

  • Hodgkin's Disease

    Clin Exp Dermatol. 2008 Jul;33(4):465-8. doi: 10.1111/j.1365-2230.2008.02730.x. Epub 2008 May 6. Author information 1 Department of Dermatology, Metz-Thionville General Hospital, Metz, France. alidadban@gmail.com Abstract The presence of coexistent disseminated granuloma annulare (GA) and Hodgkin's disease (HD) is rare,[…][ncbi.nlm.nih.gov]

  • Fetal Erythroblastosis

    Fetal erythroblastosis is a condition that occurs when the fetus and the mother are incompatible regarding the blood group, leading to fetal hemolytic anemia. Antigens in the RH0(D), Cc, Lutheran, EE, Diego, Xg, Kell, Kidd, Duffy and P systems are involved, but not incompatibilities of AB0 blood types. The mechanism of[…][symptoma.com]

  • Anemia due to Vitamin B6 Deficiency

    Platelet Count Platelets are fragments of cells that participate in clotting. They initiate repair of blood vessel walls.[drkaslow.com] MCHC is increased in and decreased in the same conditions as the MCV. Two exceptions – in spherocytosis, the MCHC is elevated but not in pernicious anemia.[drkaslow.com]

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com]

  • Aplastic Anemia

    Read More on This Topic blood disease: Normocytic normochromic anemias In aplastic anemia the normally red marrow becomes fatty and yellow and fails to form enough of its[britannica.com] After 11 cycles of PEM maintenance therapy, the patient's platelet count decreased, and progressed to pancytopenia within two months.[ncbi.nlm.nih.gov] normochromic anemia, inadequate reticulocyte response Constitutional aplastic anemia Generally, only 3 clinically significant disorders: Fanconi anemia , dyskeratosis congenita[pathologyoutlines.com]

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